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Primary immunodeficiencies (severe)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (18)Treatment guideline (8)Randomized Research (24)Phase 3 study (20)Systematic review (12)Clinical Research (661)Review article (238)Early study (phase 1 or 2) (8)Case descriptions (290)Laboratory or animal research (22)Commentary or Editorial (18)Retracted publication (1) Studies currently recruiting participants only (34)

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Publications and studies (2086)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate the Efficacy, Tolerability and Safety of Octanorm in Patients With Primary Immunodeficiency Diseases (2020-03-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Treatment of Granulomatous and Lymphocytic Interstitial Lung Disease in Patients With Common Variable Immunodeficiency (2020-03-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, Patient Satisfaction and Cost of 16.5% Subcutaneous Immunoglobulin (Cutaquig®) Treatment (2020-03-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Breadth of Donor Options for People With Inherited Diseases Requiring Allogeneic Hematopoietic Stem Cell Transplant in the Era of Alternative Donor Transplants Using Post-Transplantation Cyclophosphamide (2020-02-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluation of the Effectiveness of a Quality Improvement Intervention (2020-02-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Alemtuzumab, Fludarabine Phosphate, and Total-Body Irradiation Followed by a Donor Stem Cell Transplant in Treating Patients With Immunodeficiency or Other Nonmalignant Inherited Disorders (2020-02-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. HIV & Drug Abuse Prevention for South African Men (2020-02-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy of Treatment Intensification With Maraviroc on HIV-1 Viral Latency in Recently Infected HIV-1 naïve Patients Starting Raltegravir Plus Tenofovir/Emtricitabine (2020-01-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multi-center Clinical Study of Cord Blood Stem Cell Transplantation for SCID (2020-01-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Relative Bioavailability Study of Two Formulations of BCX7353 (2020-01-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multivirus-specific Cytotoxic T Lymphocytes (mCTL) (2020-01-18) ♡
• Exposing HIV-1 Env: Implications for therapeutic strategies. (2019/12/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Fatal Hypogammaglobulinemia 3 Years after Rituximab in a Patient with Immune Thrombocytopenia: An Underlying Genetic Predisposition? (2019/12/28) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Primary Immunodeficiency with Severe Multi-Organ Immune Dysregulation. (2019/12/28) ♡
• Comprehensive clinical and immunological features of 62 adult patients with selective primary IgM deficiency. (2019/12/25) ♡
• Primary central nervous system lymphoma: initial features, outcome, and late effects in 75 children and adolescents. (2019/12/23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Ataxia Telangiectasia Diagnosed on Newborn Screening-Case Cohort of 5 Years' Experience. (2019/12/20) ♡
• Neuronal-derived extracellular vesicles are enriched in the brain and serum of HIV-1 transgenic rats. (2019/12/20) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. A client-centered relational framework on barriers to the integration of HIV and substance use services: a systematic review. (2019/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Novel CD3G Mutation in a Taiwanese Patient With Normal T Regulatory Function Presenting With the CVID Phenotype Free of Autoimmunity-Analysis of all Genotypes and Phenotypes. (2019/12/19) ♡
• Isolation, Transfection, and Culture of Primary Human Monocytes. (2019/12/16) ♡
• Mother to Child Transmission of HIV and Associated Factors Among HIV Exposed Infants at Public Health Facilities, Dessie Town, Ethiopia. (2019/12/12) ♡
• Efficacy and Tolerability of Lopinavir/Ritonavir- and Efavirenz-Based Initial Antiretroviral Therapy in HIV-1-Infected Patients in a Tertiary Care Hospital in Beijing, China. (2019/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring the RNA Gap for Improving Diagnostic Yield in Primary Immunodeficiencies. (2019/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hematopoietic Cell Transplantation for MHC Class II Deficiency. (2019/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current Understanding and Recent Developments in Common Variable Immunodeficiency Associated Autoimmunity. (2019/12/10) ♡
• [Effect of comprehensive AIDS intervention among men aged 50 or over who had non-marital sexual behavior]. (2019/12/10) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Two cases of laryngeal obstruction with hereditary angioedema]. (2019/12/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Intriguing Role of Interleukin 13 in the Pathophysiology of Asthma. (2019/12/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. When Zoster Virus Hides a Primary Brain Lymphoma. (2019/12/05) ♡
• Total Hip Arthroplasty in a Low-Income Country: Ten-Year Outcomes from the National Joint Registry of the Malawi Orthopaedic Association. (2019/12/05) ♡
• HIV-1 Reverse Transcriptase Promotes Tumor Growth and Metastasis Formation via ROS-Dependent Upregulation of Twist. (2019/12/02) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Generation of a human induced pluripotent stem cell line (PHAi003) from a primary immunodeficient patient with CD70 mutation. (2019/12/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Generation of human induced pluripotent stem cell lines from patients with selective IgA deficiency. (2019/12/01) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Pharmacokinetic properties of Privigen(®) in Japanese patients with primary immunodeficiency. (2019/12/01) ♡
• Molecular Analysis of Mycobacterium tuberculosis Isolated in the North Central Zone of Nigeria. (2019/12/01) ♡
• Genetic Protection Modifications: Moving Beyond the Binary Distinction Between Therapy and Enhancement for Human Genome Editing. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Extramedullary plasmacytoma of the kidney in an HIV-positive patient: A case report. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Atypical Omenn Syndrome Due to RAG2 Gene Mutation, a Case Report. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Tachy- and bradyarrhythmia as an initial presentation of human immunodeficiency virus-related primary cardiac lymphoma: a case report. (2019/12/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hereditary Angioedema: An Updated Experience with Patients with Angioedema in Puerto Rico. (2019/12/01) ♡
• Interleukin-1β and interleukin-6 in Common Variable Immunodeficiency and their association with subtypes of B cells and response to the Pneumovax-23 vaccine. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Generalized lymphadenopathy: an unusual presentation of burkitt lymphoma in a Nigerian child: a case report. (2019/12/01) ♡
• Noncystic Fibrosis Bronchiectasis: Evaluation of an Extensive Diagnostic Protocol in Determining Pediatric Lung Disease Etiology. (2019/12/01) ♡
• [Severe combined immunodeficiency: The time for newborn screening has come]. (2019/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [BCG vaccine administration schedule and primary immunodeficiencies: Is it time for a change?]. (2019/12/01) ♡
• Optimal control modulation of HIV reservoir formation rate by antigen infusion. (2019/12/01) ♡
• Tuberculosis in prison and aspects associated with the diagnosis site. (2019/11/30) ♡
• Pathogenic CARD11 mutations affect B cell development and differentiation through a noncanonical pathway. (2019/11/29) ♡
• Phenotypical T Cell Differentiation Analysis: A Diagnostic and Predictive Tool in the Study of Primary Immunodeficiencies. (2019/11/29) ♡

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