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Primary immunodeficiencies (severe)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (18)Treatment guideline (8)Randomized Research (24)Phase 3 study (20)Systematic review (12)Clinical Research (661)Review article (238)Early study (phase 1 or 2) (8)Case descriptions (290)Laboratory or animal research (22)Commentary or Editorial (18)Retracted publication (1) Studies currently recruiting participants only (34)

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Publications (1486)

• Primary Immunodeficiencies: Epidemiology in the Maghreb. (2018/10/01) ♡
• A road less travelled: Clinical comparison of HIV seropositive and seronegative patients with cystoisosporiasis - An 11-year experience from a tertiary care centre in Northern India. (2018/10/01) ♡
• T cell dynamics and response of the microbiota after gene therapy to treat X-linked severe combined immunodeficiency. (2018/09/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging Aspergillus Species Almost Exclusively Associated With Primary Immunodeficiencies. (2018/09/26) ♡
• Increased Risk for Malignancies in 131 Affected CTLA4 Mutation Carriers. (2018/09/10) ♡
• Donor milk intake and infant growth in a South African neonatal unit: a cohort study. (2018/09/04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An actin cytoskeletal barrier inhibits lytic granule release from natural killer cells in patients with Chediak-Higashi syndrome. (2018/09/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Efficacy of lentivirus-mediated gene therapy in an Omenn syndrome recombination-activating gene 2 mouse model is not hindered by inflammation and immune dysregulation. (2018/09/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. A Novel Mutation in CD40LG Gene Causing X-Linked Hyper IgM Syndrome. (2018/09/01) ♡
• Prevalence of Cryptosporidium, Blastocystis, and other opportunistic infections in patients with primary and acquired immunodeficiency. (2018/09/01) ♡
• Health supervision for people with Bloom syndrome. (2018/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Monogenic Intestinal Epithelium Defects and the Development of Inflammatory Bowel Disease. (2018/09/01) ♡
• The role of neutrophils in host defense against invasive fungal infections. (2018/09/01) ♡
• Contemporary women prisoners health experiences, unique prison health care needs and health care outcomes in sub Saharan Africa: a scoping review of extant literature. (2018/08/06) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Intranasal tissue necrosis associated with opioid abuse: Case report and systematic review. (2018/08/01) ♡
• Protease Inhibitors and Cardiovascular Outcomes in Patients With HIV and Heart Failure. (2018/07/31) ♡
• Evaluation of non-adherence to anti-retroviral therapy, the associated factors and infant outcomes among HIV-positive pregnant women: a prospective cohort study in Lesotho. (2018/07/31) ♡
• A Cross Sectional Study of the Impact of Human Immunodeficiency Virus, Hepatitis B Virus and Hepatitis C Virus on Rheumatoid Factor Production. (2018/07/31) ♡
• Determinants of HIV infection among children born to mothers on prevention of mother to child transmission program of HIV in Addis Ababa, Ethiopia: a case control study. (2018/07/13) ♡
• R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome. (2018/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A 2-Year-Old Boy With Difficulty Waking After Bone Marrow Transplantation. (2018/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A case of hepatic Kaposi's sarcoma diagnosed by transgastric biopsy. (2018/07/01) ♡
• Awareness of needle-stick injuries among health-care workers in a tertiary health-care center. (2018/07/01) ♡
• Cyclin-dependent kinase 7 (CDK7)-mediated phosphorylation of the CDK9 activation loop promotes P-TEFb assembly with Tat and proviral HIV reactivation. (2018/06/29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Investigating the interaction between human immunodeficiency virus, nutrition, and disability: A cross-sectional observational study. (2018/06/20) ♡
• Pathways of care for HIV infected children in Beira, Mozambique: pre-post intervention study to assess impact of task shifting. (2018/06/07) ♡
• Pancreatic cancer screening in high-risk individuals with germline genetic mutations. (2018/06/01) ♡
• Nuclear factor erythroid 2-related factor 2-antioxidant activation through the action of ataxia telangiectasia-mutated serine/threonine kinase is essential to counteract oxidative stress in bovine mammary epithelial cells. (2018/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. New onset colitis in an adult patient with chronic granulomatous disease treated with hematopoietic stem cell transplantation: a diagnostic dilemma. (2018/05/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The promising role of monoclonal antibodies for immunotherapy of the HIV-associated cancer, non-Hodgkin lymphoma. (2018/05/04) ♡
• WASP-mediated regulation of anti-inflammatory macrophages is IL-10 dependent and is critical for intestinal homeostasis. (2018/05/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Clinical and molecular analysis of two Chinese siblings with Bloom syndrome]. (2018/05/02) ♡
• Telangiectasias in Ataxia Telangiectasia: Clinical significance, role of ATM deficiency and potential pathophysiological mechanisms. (2018/05/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Genetic and Structural Analysis of a SKIV2L Mutation Causing Tricho-hepato-enteric Syndrome. (2018/05/01) ♡
• Distinct chromatin functional states correlate with HIV latency reactivation in infected primary CD4(+) T cells. (2018/05/01) ♡
• Qualitative impact assessment of an educational workshop on primary care practitioner attitudes to NICE HIV testing guidelines. (2018/04/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neurologic disease in feline immunodeficiency virus infection: disease mechanisms and therapeutic interventions for NeuroAIDS. (2018/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Multiple facets of ADA2 deficiency: Vasculitis, auto-inflammatory disease and immunodeficiency: A literature review of 135 cases from literature]. (2018/04/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Subcutaneous immunoglobulin for the treatment of deep morphoea in a child. (2018/04/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Cost of Tuberculosis Diagnosis and Treatment in Patients with HIV: A Systematic Literature Review. (2018/04/01) ♡
• Complications Associated with Underweight Primary Immunodeficiency Patients: Prevalence and Associations Within the USIDNET Registry. (2018/04/01) ♡
• Abdominal rectus muscle pyomyositis: Report of a case and review of the literature. (2018/03/29) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Locally Ablative Radiation Therapy of a Primary Human Small Cell Lung Cancer Tumor Decreases the Number of Spontaneous Metastases in Two Xenograft Models. (2018/03/15) ♡
• Urine colorimetry for therapeutic drug monitoring of pyrazinamide during tuberculosis treatment. (2018/03/01) ♡
• Conventional and Single-Molecule Targeted Sequencing Method for Specific Variant Detection in IKBKG while Bypassing the IKBKGP1 Pseudogene. (2018/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recent advances in understanding the pathogenesis and management of reticular dysgenesis. (2018/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Modulatory effect of voriconazole on the production of proinflammatory cytokines in experimental cryptococcosis in mice with severe combined immunodeficiency. (2018/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Should Antibiotic Prophylaxis Be Routinely Used in Patients with Antibody-Mediated Primary Immunodeficiency? (2018/03/01) ♡
• Mathematical Analysis of the Transmission Dynamics of HIV Syphilis Co-infection in the Presence of Treatment for Syphilis. (2018/03/01) ♡
• Immunogenetic factors in early immune control of human immunodeficiency virus type 1 (HIV-1) infection: Evaluation of HLA class I amino acid variants in two African populations. (2018/03/01) ♡

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