← All diseases Rare and hereditary disorders

Primary immunodeficiencies (severe)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (18)Treatment guideline (8)Randomized Research (24)Phase 3 study (20)Systematic review (12)Clinical Research (661)Review article (238)Early study (phase 1 or 2) (8)Case descriptions (290)Laboratory or animal research (22)Commentary or Editorial (18)Retracted publication (1) Studies currently recruiting participants only (34)

Filter

Publications and studies (2086)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. CARMIL2-related immunodeficiency manifesting with photosensitivity. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Immunodeficiency and inborn disorders of vitamin B12 and folate metabolism. (2020/07/01) ♡
• Biochemical analysis of patients with mutations in MTHFD1 and a diagnosis of methylenetetrahydrofolate dehydrogenase 1 deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. An Update on XMEN Disease. (2020/07/01) ♡
• A Comparative Analysis of Cardiovascular Risk in Human Immunodeficiency Virus-Seropositive and -Seronegative Pre-Menopausal Women. (2020/07/01) ♡
• [Complement deficiencies]. (2020/07/01) ♡
• [Clinical characteristics of primary immunodeficiencies in children from a tertiary hospital]. (2020/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Registry of Inborn errors of immunity in a pediatric hospital]. (2020/07/01) ♡
• Profile of hematological abnormalities and its correlation with absolute CD4 count and human immunodeficiency virus viral load in human immunodeficiency virus-infected patients in a tertiary care hospital. (2020/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Herpes simplex virus type 2 meningitis as a manifestation of Good's syndrome. (2020/06/01) ♡
• Vaccine-derived rotavirus strains in infants in England. (2020/06/01) ♡
• Stigma, isolation, and depression among older adults living with HIV in rural areas. (2020/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Development of non-nucleoside reverse transcriptase inhibitors (NNRTIs): our past twenty years. (2020/06/01) ♡
• SEROPREVALENCE AND RISK FACTORS OF HERPES SIMPLEX VIRUS TYPE 2 AMONGST PATIENTS' ATTENDING RETROVIRAL CLINIC IN FEDERAL MEDICAL CENTER ABEOKUTA, SOUTH-WEST NIGERIA. (2020/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An IL17RA frameshift variant in a Holstein cattle family with psoriasis-like skin alterations and immunodeficiency. (2020/05/24) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Socio-demographic characteristics and risk factors for HIV transmission in female bar workers in sub-Saharan Africa: a systematic literature review. (2020/05/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Very Early Onset Inflammatory Bowel Disease: A Clinical Approach With a Focus on the Role of Genetics and Underlying Immune Deficiencies. (2020/05/12) ♡
• Increased HIV infection in patients with stroke in Spain. A 16-year population-based study. (2020/05/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long-term outcome of LRBA deficiency in 76 patients after various treatment modalities as evaluated by the immune deficiency and dysregulation activity (IDDA) score. (2020/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Tuberculosis: a focused review for the emergency medicine clinician. (2020/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. How mycobacteria take advantage of the weakness in human immune system in the modern world. (2020/04/01) ♡
• Development and psychometric evaluation of the patient's HIV knowledge questionnaire (PHKQ). (2020/04/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel Hemizygous IL2RG p.(Pro58Ser) Mutation Impairs IL-2 Receptor Complex Expression on Lymphocytes Causing X-Linked Combined Immunodeficiency. (2020/04/01) ♡
• Education, Race/Ethnicity, and Causes of Premature Mortality Among Middle-Aged Adults in 4 US Urban Communities: Results From CARDIA, 1985-2017. (2020/04/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. EBV-directed viral-specific T-lymphocyte therapy for the treatment of EBV-driven lymphoma in two patients with primary immunodeficiency and DNA repair defects. (2020/03/01) ♡
• Structural Noninfectious Manifestations of the Central Nervous System in Common Variable Immunodeficiency Disorders. (2020/03/01) ♡
• The influence of clinical features mimicking primary immunodeficiency diseases (mPID) on children with Langerhans cell histiocytosis (LCH) - Four with mPID among 39 LCH children from one referral center during 18-year period. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. iPSC line derived from a Bloom syndrome patient retains an increased disease-specific sister-chromatid exchange activity. (2020/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Omenn Syndrome Identified by Newborn Screening. (2020/03/01) ♡
• Primary immunodeficiency disease: a cost-utility analysis comparing intravenous vs subcutaneous immunoglobulin replacement therapy in Australia. (2020/03/01) ♡
• North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition Position Paper on the Evaluation and Management for Patients With Very Early-onset Inflammatory Bowel Disease. (2020/03/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Atazanavir / ritonavir versus Lopinavir / ritonavir-based combined antiretroviral therapy (cART) for HIV-1 infection: a systematic review and meta-analysis. (2020/03/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Genetic Screening of the Patients with Primary Immunodeficiency by Whole-Exome Sequencing. (2020/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Somatic mosaicism and common genetic variation contribute to the risk of very-early-onset inflammatory bowel disease. (2020/02/21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evolocumab treatment in patients with HIV and hypercholesterolemia/mixed dyslipidemia: BEIJERINCK study design and baseline characteristics. (2020/02/01) ♡
• Chest Radiographs for Distinguishing ADA-SCID from Other Forms of SCID. (2020/02/01) ♡
• Expanding Clinical Phenotype and Novel Insights into the Pathogenesis of ICOS Deficiency. (2020/02/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Health-Related Quality of Life and Emotional Difficulties in Chronic Granulomatous Disease: Data on Adult and Pediatric Patients from Italian Network for Primary Immunodeficiency (IPINet). (2020/02/01) ♡
• The HIV-Tat protein interacts with Sp3 transcription factor and inhibits its binding to a distal site of the sod2 promoter in human pulmonary artery endothelial cells. (2020/02/01) ♡
• Diversity of XMEN Disease: Description of 2 Novel Variants and Analysis of the Lymphocyte Phenotype. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A novel de novo NLRC4 mutation reinforces the likely pathogenicity of specific LRR domain mutation. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Eczematous dermatitis in primary immunodeficiencies: A review of cutaneous clues to diagnosis. (2020/02/01) ♡
• RAD50 regulates mitotic progression independent of DNA repair functions. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Perianal Disease and Granulomas: Think Out of the Box…. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Guillain-Barré Syndrome and Hydrocephalus in an infant with Wiskott-Aldrich Syndrome. (2020/02/01) ♡
• X-linked lymphoproliferative syndrome in mainland China: review of clinical, genetic, and immunological characteristic. (2020/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The Many Faces of XMEN Disease, Report of Two Patients with Novel Mutations. (2020/02/01) ♡
• Inhibitory effect of alpha-lipoic acid on mitochondrial dysfunction and interleukin-8 expression in interleukin-1beta-stimulated ataxia teleangiectasia fibroblasts. (2020/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Modeling HIV Pre-Exposure Prophylaxis. (2020/01/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Newborn Screening for Primary Immunodeficiencies: The Gaps, Challenges, and Outlook for Developing Countries. (2020/01/30) ♡

↑ Back to top

codex.care does not provide medical advice. Always discuss symptoms, medication, and treatment choices with your own healthcare provider.