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Primary immunodeficiencies (severe)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (18)Treatment guideline (8)Randomized Research (24)Phase 3 study (20)Systematic review (12)Clinical Research (661)Review article (238)Early study (phase 1 or 2) (8)Case descriptions (290)Laboratory or animal research (22)Commentary or Editorial (18)Retracted publication (1) Studies currently recruiting participants only (34)

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Publications and studies (2086)

• LXR signaling controls homeostatic dendritic cell maturation. (2023/05/12) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Systematic review: Safety of surgical male circumcision in context of HIV prevention public health programmes. (2023/05/03) ♡
• The Autoimmune Manifestations in Patients with Genetic Defects in the B Cell Development and Differentiation Stages. (2023/05/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of nonalcoholic fatty liver disease on clinical outcomes in patients with COVID-19 among persons living with HIV: A multicenter research network study. (2023/05/01) ♡
• Proposal to Screen for Zinc and Selenium in Patients with IgA Deficiency. (2023/04/29) ♡
• Autoimmune versus Non-autoimmune Cutaneous Features in Monogenic Patients with Inborn Errors of Immunity. (2023/04/24) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Presentation of a Patient with a Congenital Disorder of Glycosylation, Type IIs (ATP6AP1), and Liver Transplantation. (2023/04/18) ♡
• Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19. (2023/04/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. From the archives of MD Anderson Cancer Center: Primary effusion lymphoma with simultaneous involvement of the retroperitoneum and pleural cavity. (2023/04/01) ♡
• Epidemiology, Management, and Treatment Access of Hereditary Angioedema in the Asia Pacific Region: Outcomes From an International Survey. (2023/04/01) ♡
• Contribution of genetic variants associated with primary immunodeficiencies to childhood-onset systemic lupus erythematous. (2023/04/01) ♡
• Insights into the pathogenesis of hereditary angioedema using genetic sequencing and recombinant protein expression analyses. (2023/04/01) ♡
• Discovery of a first-in-class orally available HBV cccDNA inhibitor. (2023/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. ATR Inhibition in Advanced Urothelial Carcinoma. (2023/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Is Your Kid Actin Out? A Series of Six Patients With Inherited Actin-Related Protein 2/3 Complex Subunit 1B Deficiency and Review of the Literature. (2023/04/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fecal Microbiota Transplantation for Clostridioides difficile Infection in Immunocompromised Pediatric Patients. (2023/04/01) ♡
• Proteomic characterization and comparison of milk fat globule membrane proteins of Saanen goat milk from 3 habitats in China using SWATH-MS technique. (2023/04/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Adaptive Strategies for Retention in Care among Persons Living with HIV. (2023/04/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Comparative efficacy and acceptability of non-pharmacological interventions for depression in people living with HIV: A systematic review and network meta-analysis. (2023/04/01) ♡
• Dysphagia and pill swallowing in HIV/AIDS in South Africa: Results of a scoping review. (2023/03/31) ♡
• Cow's milk alternatives for children with cow's milk allergy and beyond. (2023/03/28) ♡
• B cells and T cells abnormalities in patients with selective IgA deficiency. (2023/03/20) ♡
• Striking differences in weight gain after cART initiation depending on early or advanced presentation: results from the ANRS CO4 FHDH cohort. (2023/03/02) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. ASCENIV utilization in a primary immunodeficiency patient with recurrent viral infections. (2023/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hereditary angioedema and COVID-19 during pregnancy: Two case reports. (2023/03/01) ♡
• Granulomatous inflammation and hypogammaglobulinemia: Clinical conundrum of familial hemophagocytic lymphohistiocytosis type 5. (2023/03/01) ♡
• Treatment guidelineiAn official agreement between doctors about how this disease should be treated. This is not a single study but the conclusion of an entire medical field. Genomic diagnosis and care co-ordination for monogenic inflammatory bowel disease in children and adults: consensus guideline on behalf of the British Society of Gastroenterology and British Society of Paediatric Gastroenterology, Hepatology and Nutrition. (2023/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. How do nuclear factor kappa B (NF-κB)1 and NF-κB2 defects lead to the incidence of clinical and immunological manifestations of inborn errors of immunity? (2023/03/01) ♡
• Identification of phytochemical compounds of Fagopyrum dibotrys and their targets by metabolomics, network pharmacology and molecular docking studies. (2023/03/01) ♡
• Tui Na for painful peripheral neuropathy in people with human immunodeficiency virus: A randomized, double-blind, placebo-controlled trial protocol. (2023/02/23) ♡
• Demographic, clinical, immunological, and molecular features of iranian national cohort of patients with defect in DCLRE1C gene. (2023/02/21) ♡
• New Presentation of CD27 Deficiency; Coronary Ectasia and COVID-19. (2023/02/20) ♡
• Inborn errors of OAS-RNase L in SARS-CoV-2-related multisystem inflammatory syndrome in children. (2023/02/10) ♡
• Human CARMIL2 deficiency underlies a broader immunological and clinical phenotype than CD28 deficiency. (2023/02/06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Low rates of headache and migraine associated with intravenous immunoglobulin infusion using a 15-minute rate escalation protocol in 123 patients with primary immunodeficiency. (2023/02/02) ♡
• Humoral immunogenicity of COVID-19 vaccines in patients with coeliac disease and other noncoeliac enteropathies compared to healthy controls. (2023/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The Effect of N-Acetyl-DL-Leucine on Neurological Symptoms in a Patient with Ataxia-Telangiectasia: a Case Study. (2023/02/01) ♡
• Characterization of Expanded Gamma Delta T Cells from Atypical X-SCID Patient Reveals Preserved Function and IL2RG-Mediated Signaling. (2023/02/01) ♡
• CVID-Associated B Cell Activating Factor Receptor Variants Change Receptor Oligomerization, Ligand Binding, and Signaling Responses. (2023/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acute bacterial encephalitis complicated with recurrent nasopharyngeal carcinoma associated with Elizabethkingia miricola infection: A case report. (2023/01/27) ♡
• Clinical and Immunologic Characteristics of Non-Hematologic Cancers in Patients with Inborn Errors of Immunity. (2023/01/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case report: Primary immunodeficiency due to a novel mutation in CARMIL2 and its response to combined immunomodulatory therapy. (2023/01/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sinonasal diffuse large B-cell lymphoma in a patient with Wiskott-Aldrich syndrome: A case report and literature review. (2023/01/12) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: Updates on the pathogenesis of common variable immunodeficiency (CVID). (2023/01/10) ♡
• Diagnostic challenge in a series of eleven patients with hyper IgE syndromes. (2023/01/10) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Persistent dyselectrolytemia in a neonate induced by liposomal amphotericin B. A case report. (2023/01/10) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Crossing a rugged road in a primary immune regulatory disorder. (2023/01/09) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Autosomal dominant chronic mucocutaneous candidiasis with STAT1 mutation can be associated with chronic active hepatitis: A case report. (2023/01/06) ♡
• National experience with adenosine deaminase deficiency related SCID in Polish children. (2023/01/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case report: Pneumocystis jirovecii pneumonia in a severe case of Aicardi-Goutières syndrome with an IFIH1 gain-of-function mutation mimicking combined immunodeficiency. (2023/01/04) ♡

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