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Primary immunodeficiencies (severe)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (82)Meta-analysis (18)Treatment guideline (8)Randomized Research (24)Phase 3 study (20)Systematic review (12)Clinical Research (661)Review article (238)Early study (phase 1 or 2) (8)Case descriptions (290)Laboratory or animal research (22)Commentary or Editorial (18)Retracted publication (1) Studies currently recruiting participants only (34)

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Publications and studies (2086)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Immune Globulin Subcutaneous (Human), 20% Solution (IGSC, 20%) in Japanese Participants With Primary Immunodeficiency Diseases (PID) (2024-03-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy, Safety, and Pharmacokinetics of Shu Yang IVIG (2024-03-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluation of Adult Patients With Immunodeficiency Within the Scope of the ICF (2024-02-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Whole Body MRI for Cancer Surveillance in A-T (2024-02-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Retroviral Insertion Site Methodology Study (2024-01-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Angioedema Biomarker Research Study (2024-01-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Prevalence of Oral HPV Infection and Oral Lesions in People Living With HIV (2024-01-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of STAR-0215 in Healthy Adult Participants (2024-01-11) ♡
• [Controversies, difficulties and changes in serological confirmatory testing]. (2023/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. BCL10 Deficiency Presenting as Severe Combined Immunodeficiency Escaping Newborn Screening. (2023/12/30) ♡
• Avoidance of healthcare service use and correlates among HIV-positive patients in Vietnam: a cross-sectional study. (2023/12/30) ♡
• PIM Kinase Inhibition Attenuates the Malignant Progression of Metastatic Hepatoblastoma. (2023/12/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Modulating the PI3K Signalling Pathway in Activated PI3K Delta Syndrome: a Clinical Perspective. (2023/12/27) ♡
• Hyperactive Rac stimulates cannibalism of living target cells and enhances CAR-M-mediated cancer cell killing. (2023/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cellular proteins as potential targets for antiretroviral therapy. (2023/12/26) ♡
• Identifying immunodeficiency status in children with pulmonary tuberculosis: using radiomics approach based on un-enhanced chest computed tomography. (2023/12/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Disseminated histoplasmosis in an HIV/AIDS transgender male-to-female with atypical and persistent GI manifestations. (2023/12/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel Compound Heterozygous ZAP70 R37G A507T Mutations in Infant with Severe Immunodeficiency. (2023/12/22) ♡
• Plasma Levels of mir-34a-5p Correlate with Systemic Inflammation and Low Naïve CD4 T Cells in Common Variable Immunodeficiency. (2023/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Inherited Human BCL10 Deficiencies. (2023/12/22) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Prevalence and Characteristics of Non-tuberculous Mycobacteria (NTM) Infection in Recipients of Allogeneic Hematopoietic Stem Cell Transplantation: a Systematic Review and Meta-analysis. (2023/12/22) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Clinical and Immunological Features, Genetic Variants, and Outcomes of Patients with CD40 Deficiency. (2023/12/22) ♡
• Evaluation of Clinical and Immunological Alterations Associated with ICF Syndrome. (2023/12/22) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 1 Open-Label Study to Assess the Tolerability, Safety, and Immunogenicity of Hyaluronidase-Facilitated Subcutaneous Immunoglobulin 20% in Healthy Adults. (2023/12/22) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Proposal for a Disease Activity Score and Disease Damage Score for ADA2 Deficiency: the DADA2AI and DADA2DI. (2023/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Human GP130 Cytokine Receptor and Its Expression-an Atlas and Functional Taxonomy of Genetic Variants. (2023/12/22) ♡
• Influence of invasive aspergillosis during acute leukaemia treatment on survival after allogeneic stem cell transplantation: a prospective study of the EBMT Infectious Diseases Working Party. (2023/12/22) ♡
• A Study on Knowledge, Attitude, and Practice Related to Sexually Transmitted Infections Among Students of Nonmedical Background in Manipal, India. (2023/12/22) ♡
• Syphilis: Is it Back with a Bang? (2023/12/22) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Doxycycline Prophylaxis to Prevent Sexually Transmitted Infections in Women. (2023/12/21) ♡
• Chromatin regulator SMARCAL1 modulates cellular lipid metabolism. (2023/12/21) ♡
• Antioxidants and azd0156 Rescue Inflammatory Response in Autophagy-Impaired Macrophages. (2023/12/21) ♡
• UK-5099, a mitochondrial pyruvate carrier inhibitor, recovers impaired neutrophil maturation caused by AK2 deficiency in human pluripotent stem cell models. (2023/12/20) ♡
• Large-scale deep learning analysis to identify adult patients at risk for combined and common variable immunodeficiencies. (2023/12/20) ♡
• Portal hypertension in common variable immunodeficiency disorders - a single center analysis on clinical and immunological parameter in 196 patients. (2023/12/20) ♡
• Combined Immunodeficiency Caused by a Novel Nonsense Mutation in LCK. (2023/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Infliximab as successful treatment option in a case of adenosine deaminase 2 deficiency. (2023/12/19) ♡
• Meningitis in critically ill patients admitted to intensive care unit for severe community-acquired pneumococcal pneumonia. (2023/12/18) ♡
• Anesthetic Challenges And Management In Patient With Ataxia-Telangiectasia. (2023/12/18) ♡
• Infectious diseases in Afghanistan: Strategies for health system improvement. (2023/12/18) ♡
• Methamphetamine enhancement of HIV-1 gp120-mediated NLRP3 inflammasome activation and resultant proinflammatory responses in rat microglial cultures. (2023/12/16) ♡
• Hemophagocytic lymphohistiocytosis in children with Griscelli syndrome type 2: genetics, laboratory findings and treatment. (2023/12/15) ♡
• Genotype, oxidase status, and preceding infection or autoinflammation do not affect allogeneic HCT outcomes for CGD. (2023/12/14) ♡
• Assessing Knowledge of, Experience with, and Willingness to Prescribe Hormone Therapy to Transgender Individuals with HIV: A National Survey of HIV Practitioners. (2023/12/13) ♡
• Genetic Characteristics of Patients with Young-Onset Myelodysplastic Neoplasms. (2023/12/13) ♡
• Racial disparities in septic shock mortality: a retrospective cohort study. (2023/12/12) ♡
• Risk of severe COVID-19 outcomes after autumn 2022 COVID-19 booster vaccinations: a pooled analysis of national prospective cohort studies involving 7.4 million adults in England, Northern Ireland, Scotland and Wales. (2023/12/12) ♡
• Assessment of community pharmacies readiness to dispense antiretroviral medicines in Rwanda. (2023/12/12) ♡
• Facilitators and barriers to integration of noncommunicable diseases with HIV care at primary health care in Ethiopia: a qualitative analysis using CFIR. (2023/12/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Modulation of Epstein-Barr-Virus (EBV)-Associated Cancers by Co-Infections. (2023/12/07) ♡

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