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Mitochondrial diseases

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (34)Meta-analysis (3)Treatment guideline (1)Systematic review (16)Randomized trial (11)Phase 3 study (3)Clinical Trial (599)Review article (684)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (269)Case Description (79)Commentary or Editorial (11)Retracted Publication (9) Studies currently recruiting participants only (30)

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Publications and studies (3448)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Combined Antioxidant Therapy on Oxidative Stress, Mitochondrial Dysfunction Markers in Diabetic Retinopathy (2022-04-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondrial Function in Patients With Severe Liver Disease (2022-03-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate Efficacy, Safety, Tolerability and Exposure After a Repeat-dose of Sepofarsen (QR-110) in LCA10 (ILLUMINATE) (2022-03-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Oxidative Capacity and Exercise Tolerance in Ambulatory SMA (2022-03-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Novel Role of Alpha Lipoic Acid in Comparison With Selenium in Mitochondrial Resuscitation and miRNA-126 Expression in Hemodialysis Patients (2022-03-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Glutamine Supplement in MELAS (Mitochondrial Encephalopathy, Lactic Acidosis, and Stroke-like Episodes) Syndrome (2022-02-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Role of Mitochondrial Dysfunction in the Occurrence of Acute Kidney Injury (AKI) in Postoperative Cardiac Surgery (2022-02-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Determine Range of Tissue Frataxin Concentrations and Other Potential Biomarkers (2022-02-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ABI-009 (NAB sirolimus) in Patients With Genetically-confirmed Leigh or Leigh-like Syndrome (2022-02-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Trial to Evaluate Safety and Efficacy of Elamipretide Primary Mitochondrial Myopathy Followed by Open-Label Extension (2022-01-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An Exploratory Open Label Study of EPI-743 (Vincerinone TM) in Children With Autism Spectrum Disorder (2022-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of Acipimox on Insulin Action, Vascular Function, and Muscle Function in Type 1 Diabetes (2022-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Metformin on Vascular and Mitochondrial Function in Type 1 Diabetes (2022-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Spa Rehabilitation, Antioxidant and Bioenergetic Supportive Treatment of Patients With Post-Covid-19 Syndrome (2022-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Associations of FGF21 and GDF15 with mitochondrial dysfunction in children living with perinatally-acquired HIV: A cross-sectional evaluation of pediatric AIDS clinical trials group 219/219C. (2021/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New insights of epigenetics in vascular and cellular senescence. (2021/12/31) ♡
• Melatonin and Epilepsy. (2021/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Role of Vascular Aging in the Pathogenesis of Abdominal Aortic Aneurysm and Potential Therapeutic Targets]. (2021/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial Dysfunction as a Hallmark of Environmental Injury. (2021/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Conplastic strains for identification of retrograde effects of mitochondrial dna variation on cardiometabolic traits in the spontaneously hypertensive rat. (2021/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Coenzyme Q10 effects in neurological diseases. (2021/12/30) ♡
• Extracellular vesicles from mesenchymal stem cells of dental pulp and adipose tissue display distinct transcriptomic characteristics suggestive of potential therapeutic targets. (2021/12/30) ♡
• Hepatic MIR20B promotes non-alcoholic fatty liver disease by suppressing PPARA. (2021/12/29) ♡
• Multiple Mechanisms Converging on Transcription Factor EB Activation by the Natural Phenol Pterostilbene. (2021/12/28) ♡
• SKP-SC-EVS Mitigate Denervated Muscle Atrophy by Inhibiting Oxidative Stress and Inflammation and Improving Microcirculation. (2021/12/28) ♡
• Mitochondrial C5Ar1 activity in macrophages controls IL-1β production underlying sterile inflammation. (2021/12/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ageing, Age-Related Cardiovascular Risk and the Beneficial Role of Natural Components Intake. (2021/12/24) ♡
• High-Fat Diet-Induced Mitochondrial Dysfunction Promotes Genioglossus Injury - A Potential Mechanism for Obstructive Sleep Apnea with Obesity. (2021/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Indy-from Flies to Worms, Mice, Rats, Non-Human Primates, and Humans. (2021/12/23) ♡
• Metabolic reprogramming during hyperammonemia targets mitochondrial function and postmitotic senescence. (2021/12/22) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A New Strategy to Preserve and Assess Oxygen Consumption in Murine Tissues. (2021/12/22) ♡
• Phase 1 Clinical Trial of Elamipretide in Intermediate Age-Related Macular Degeneration and High-Risk Drusen: RecLaim High-Risk Drusen Study. (2021/12/22) ♡
• Transcriptomic Analysis Reveals the Protective Effects of Empagliflozin on Lipid Metabolism in Nonalcoholic Fatty Liver Disease. (2021/12/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolic Therapy of Heart Failure: Is There a Future for B Vitamins? (2021/12/21) ♡
• Zhen-Wu-Tang Induced Mitophagy to Protect Mitochondrial Function in Chronic Glomerulonephritis via PI3K/Akt/mTOR and AMPK Pathways. (2021/12/21) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Bioactive Compounds in Aegopodium podagraria Leaf Extracts and Their Effects against Fluoride-Modulated Oxidative Stress in the THP-1 Cell Line (2021/12/20) ♡
• Dietary Arginine Supplementation Improves Intestinal Mitochondrial Functions in Low-Birth-Weight Piglets but Not in Normal-Birth-Weight Piglets. (2021/12/15) ♡
• Dysregulated metabolism underpins Zika virus infection-associated impairment in fetal development. (2021/12/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Directly Reprogrammed Human Neurons to Understand Age-Related Energy Metabolism Impairment and Mitochondrial Dysfunction in Healthy Aging and Neurodegeneration. (2021/12/14) ♡
• A mitochondrial response to oxidative stress mediated by unscheduled RNA-DNA hybrids (R-loops). (2021/12/14) ♡
• Jian-Pi-Yi-Shen Formula Alleviates Chronic Kidney Disease in Two Rat Models by Modulating QPRT/NAD (+) /SIRT3/Mitochondrial Dynamics Pathway. (2021/12/13) ♡
• Zeaxanthin ameliorates obesity by activating the β3-adrenergic receptor to stimulate inguinal fat thermogenesis and modulating the gut microbiota. (2021/12/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial Oxidative Stress-A Causative Factor and Therapeutic Target in Many Diseases. (2021/12/13) ♡
• ATP Synthase K (+) - and H (+) -Fluxes Drive ATP Synthesis and Enable Mitochondrial K (+) -"Uniporter” Function: I. Characterization of Ion Fluxes. (2021/12/13) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Adipose Lipolysis Regulates Cardiac Glucose Uptake and Function in Mice under Cold Stress. (2021/12/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Bone marrow derived-mesenchymal stem cell improves diabetes-associated fatty liver via mitochondria transformation in mice. (2021/12/11) ♡
• Mitochondrial Deficits With Neural and Social Damage in Early-Stage Alzheimer's Disease Model Mice. (2021/12/10) ♡
• Mitochondrial uncoupling protein 1 antagonizes atherosclerosis by blocking NLRP3 inflammasome-dependent interleukin-1β production. (2021/12/10) ♡
• Hematopoietic Cell-Specific SLC37A2 Deficiency Accelerates Atherosclerosis in LDL Receptor-Deficient Mice. (2021/12/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial Dysfunction and Diabetic Nephropathy: Nontraditional Therapeutic Opportunities. (2021/12/09) ♡

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