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Mitochondrial diseases

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (34)Meta-analysis (3)Treatment guideline (1)Systematic review (16)Randomized trial (11)Phase 3 study (3)Clinical Trial (599)Review article (684)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (269)Case Description (79)Commentary or Editorial (11)Retracted Publication (9) Studies currently recruiting participants only (30)

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Publications and studies (3448)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Dietary protein and amino acid restriction: Roles in metabolic health and aging-related diseases. (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Strategies to protect against age-related mitochondrial decay: Do natural products and their derivatives help? (2022/01/01) ♡
• Gamma-tocopherol, a major form of vitamin E in diets: Insights into antioxidant and anti-inflammatory effects, mechanisms, and roles in disease management. (2022/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Characterizing cardiac phenotype in Friedreich's ataxia: The CARFA study. (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The cGAS-STING signaling in cardiovascular and metabolic diseases: Future novel target option for pharmacotherapy. (2022/01/01) ♡
• A novel experimental approach for the selective isolation and characterization of human RNase MRP. (2022/01/01) ♡
• Difficulties translating antisense-mediated activation of Frataxin expression from cell culture to mice. (2022/01/01) ♡
• Circulating small RNA signatures differentiate accurately the subtypes of muscular dystrophies: small-RNA next-generation sequencing analytics and functional insights. (2022/01/01) ♡
• Drug repurposing based novel anti-leishmanial drug screening using in-silico and in-vitro approaches. (2022/01/01) ♡
• Role of Oxidative Stress and Inflammation in Insomnia Sleep Disorder and Cardiovascular Diseases: Herbal Antioxidants and Anti-inflammatory Coupled with Insomnia Detection using Machine Learning. (2022/01/01) ♡
• The Role of Ketogenic Metabolic Therapy on the Brain in Serious Mental Illness: A Review. (2022/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Folate Metabolism in Hepatocellular Carcinoma. What Do We Know So Far? (2022/01/01) ♡
• Investigating the association of toll-like receptor 9 rs5743836, rs352140, and rs187084 gene polymorphisms and their mRNA levels with different hepatic fibrosis stages of non-alcoholic fatty liver patients compared to healthy controls. (2022/01/01) ♡
• Resveratrol and Astaxanthin Protect Primary Human Nasal Epithelial Cells Cultured at an Air-liquid Interface from an Acute Oxidant Exposure. (2022/01/01) ♡
• Redox Homeostasis in Well-Differentiated Primary Human Nasal Epithelial Cells. (2022/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Co-transplantation of Mesenchymal Stem Cell Derived Exosomes and Autologous Mitochondria for Patients Candidate for CABG Surgery (2022-12-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Single Case Study of Hypermetabolism (2022-12-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Chronic Kidney Disease and Heart Failure With Preserved Ejection Fraction: The Role of Mitochondrial Dysfunction (2022-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hepatocyte Transplantation for Liver Based Metabolic Disorders (2022-12-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gene Therapy Clinical Trial for the Treatment Of Leber's HereDitary Optic Neuropathy (2022-11-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Testing of NBIA Genes: Analysis of Genetic Heterogeneity and Validation of Mitochondrial Markers for Assessing Causality of Sequence Variants. (2022-11-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondria and Metabolic Syndrome in a Southern California Chinese Cohort (2022-11-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Long-Term Treatment With the Ketogenic Diet in Epilepsy (2022-10-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondria Inborn Errors of Metabolism and ANT Defects in Mitochondria Diseases (2022-10-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy, Safety, Tolerability of AXA1125 in Fatigue After COVID-19 Infection (2022-10-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients (2022-10-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Carnitine and Liver Mitochondria Fatty Acid Processing (2022-09-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondrial Health and Hemodynamic Instability Related to Renal Replacement Therapy in Critically Ill Patients (2022-09-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ACTIV- Exercise Intervention in Healthy Young Men (2022-09-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Metabolic Phenotyping in Humans (2022-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biologic Mechanisms for Pain Variation After Physical Activity in Osteoarthritis (2022-09-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The KHENERGYZE Study (2022-08-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Single and Multiple Dose Study of AMAZ-02 to Evaluate Safety and Pharmacokinetics in Elderly Subjects (2022-08-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. AMAZ-02 Effect on Exercise Tolerance in Healthy, Overweight Middle Aged Subjects (ATLAS Trial) (2022-08-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NR-SAFE: Safety of High-Dose Nicotinamide Riboside (NR) in Parkinson's Disease (2022-08-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biomarker for Friedreich's Ataxia (BioFridA) (2022-08-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of Iron Deficiency and Its Correction on Mitochondrial Metabolism of the Cardiomyocyte (MitoCardiofer) (2022-07-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Trial of Oral Glutamine on Mitochondrial Function in CKD (2022-07-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy of Oral Idebenone for Preventive Treatment of Migraine in Adult Migraine Patients (2022-06-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of COVID-19 on Platelet Mitochondrial Bioenergetic, Antioxidants and Oxidative Stress in Infertile Men (2022-06-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Insulin and Muscle Fat Metabolism (2022-06-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Dose-Finding Study of the Second Mitochondrial Activator of Caspases (SMAC) Mimetic Debio 1143 When Given in Combination With Avelumab to Participants With Advanced Solid Malignancies and to Participants With Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC) After Platinum-Based Therapy (2022-06-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess Efficacy, Long Term Safety and Tolerability of RT001 in Subjects With Friedreich's Ataxia (2022-05-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of the Natural Course of SURF1 Deficiency (2022-05-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cancer-associated Muscle Mass - Molecular Factors and Exercise Mechanisms (2022-05-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Relative Mitochondrial Toxicity of Tenofovir Alafenamide (TAF) vs. Tenofovir Disoproxil Fumarate (TDF) (2022-05-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Biomarker Study of PTC-589 in Participants With Parkinson's Disease (2022-05-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Molecular Hydrogen in Patients With NAFLD (2022-04-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondrial Biomarkers in Huntington's Disease (2022-04-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Impact of Chronic Mitochondrial Antioxidant Supplementation on CardiovascularToxicity in Breast Cancer Patients (2022-04-08) ♡

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