Mitochondrial diseases
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Publications and studies (3430)
- Mailuo Shutong pills alleviate limb swelling in femoral fracture rats by orchestrating mitophagic clearance and ferroptotic suppression. (2027/01/10) ♡
- Zhenwu Decoction ameliorates experimental benign prostatic hyperplasia: association with mitochondrial quality control, oxidative stress and apoptosis regulation. (2027/01/10) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. San Wei Tan Xiang (SWTX) ameliorates depressive-like behaviors by modulating 6-phosphogluconate dehydrogenase (6PGD) activity in mice. (2026/12/06) ♡
- Jiawei Wutou decoction attenuates knee osteoarthritis by modulating mitochondrial oxidative stress via the JAK2/STAT3 pathway: Insights from network pharmacology and experimental validation. (2026/12/06) ♡
- A new renal protective strategy: Shenfu decoction targets hypertensive renal disease through the AMPK/SIRT1/PGC-1α pathway. (2026/12/06) ♡
- Nao-xin-tong capsule attenuates cerebral ischemia/reperfusion injury by modulating the p53/GDF15/NOX4 regulatory network and alleviating mitochondrial dysfunction and ferroptosis-related injury. (2026/12/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A comprehensive review on Jiao-tai-wan: Traditional application, pharmacokinetics, and therapeutic mechanisms in multiple disorders. (2026/12/06) ♡
- Screening of hepatotoxic components of Epimedium brevicornu Maxim. by liver microfluidic-organ-chip: Icariside Ⅱ induces hepatocyte apoptosis via ROS-mediated mitochondrial dysfunction and the p38 MAPK pathway. (2026/12/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Migraine relief: Solutions from natural bioactive products of Traditional Chinese medicine. (2026/12/06) ♡
- Xijiaqi Formula attenuates myocardial infarction-induced chronic heart failure by inhibiting TGF-β1/Smads-mediated fibroblast activation. (2026/12/01) ♡
- Danggui Jixueteng Decoction protects HS-5 cells against chemotherapy-induced injury via the AKT/FOXO3a pathway to suppress excessive mitophagy and ferroptosis. (2026/11/15) ♡
- Hexokinase 2 elevation links obesity to increased risk of acute kidney injury. (2026/11/01) ♡
- Lishui Xiaozhong granules protect against diabetic retinopathy by activating PINK1/parkin-mediated mitophagy and suppressing ferroptosis. (2026/10/28) ♡
- Shengyang Xiehuo formula regulates lipid droplet-mitochondrial interaction via TNF-α/PPARγ axis to treat chronic atrophic gastritis. (2026/10/28) ♡
- Network toxicology and biolayer interferometry validation reveal the mechanism of Stelleropsis tianschanica Pobed.-induced hepatotoxicity. (2026/10/28) ♡
- Mitochondria-associated endoplasmic reticulum membranes and calcium ion exchange: A novel direction for aging and neurodegenerative diseases. (2026/10/01) ♡
- Increased oxygen demand during exercise as a stimulus for neuroprotection: A working hypothesis. (2026/10/01) ♡
- Electroacupuncture treatment enhances hippocampal growth hormone level and restores mitochondrial function in vascular dementia rats. (2026/10/01) ♡
- MGRN1 alleviates the progression of obesity-related acute lung injury by protecting lung epithelial cells through restoring mitochondrial function. (2026/10/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Natural monomer compounds in neurodegenerative diseases: Targeting ferroptosis and neuroinflammation. (2026/09/13) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. From Severe Neonatal Encephalopathy to Slowly Neurologic Progressive Disease: Pyruvate Dehydrogenase Deficiency Related to PDHA1 Variants. (2026/09/01) ♡
- When copper turns killer: Decoding copper dyshomeostasis and cuproptosis in neurodegenerative pathogenesis and precision metal interventions. (2026/09/01) ♡
- Bushen Tiaojing decoction ameliorates meiotic impairment to improve oocyte quality during aging through blocking the iron overload-induced p53/CDK1/ESPL1 pathway. (2026/09/01) ♡
- Chlorogenic acid attenuates aortic dissection in atherosclerotic mice by inhibiting ferroptosis via the Nrf2/HO-1/GPX4 axis. (2026/09/01) ♡
- Liqi Huoxue dripping pills alleviate myocardial ischemia-reperfusion injury with improved mitochondrial biogenesis and reduced ferroptosis: Involvement of S100A8/A9-TLR4-ERK signaling. (2026/09/01) ♡
- Elucidating the NETs-BNIP3-pyroptosis axis in cerebral ischemia-reperfusion injury and the intervention of Bu Yang Huan Wu decoction. (2026/09/01) ♡
- Qiteng Xiaozhuo granules activate mitophagy to alleviate chronic glomerulonephritis. (2026/09/01) ♡
- The common mechanism underlying Shuangxinfang's amelioration of post-myocardial infarction depression: Targeting S100A9/NLRP3 to improve mitochondrial energetics. (2026/09/01) ♡
- Shemazhichuan liquid alleviates airway remodeling by modulating mitochondrial dysfunction via the EIF4E/HIF-1α/ROS pathway. (2026/09/01) ♡
- Ayurvedic nutraceutical, Chyawanprash, enhances longevity and stress resilience via mitochondrial and muscular health in C. elegans model of ageing. (2026/09/01) ♡
- Network analysis and experimental validation reveal mitochondrial-mediated programmed cell death mechanisms of Sini Decoction Plus Ginseng Soup against acute liver failure. (2026/09/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Neuroprotection and prevention of oxaliplatin-induced neuropathy with Huangqi Guizhi Wuwu Decoction: a 12-center randomized, double-blind trial with mechanistic validation. (2026/09/01) ♡
- Jiao-tai-wan suppresses ferroptosis induced by heart-kidney disharmony insomnia by regulating the PDE4D/BDNF signaling pathway. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Bioactive compounds from traditional Chinese medicine for mitochondrial dysfunction-oriented nanodelivery in neurodegenerative diseases. (2026/09/01) ♡
- Cadmium induces renal injury via a BMAL1-dependent inflammatory and senescence cascade: Attenuation by Lycium barbarum polysaccharide and melatonin. (2026/09/01) ♡
- Biochanin A alleviates HFD-induced MAFLD by inhibiting IRE1α-SPT-ceramide axis and improving intestinal homeostasis. (2026/09/01) ♡
- Cinnamon polysaccharides reshape gut microbiota and enrich Alloprevotella rava to promote acetate-dependent choline metabolism and delay mammary aging. (2026/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Stable Isotope-Resolved Metabolomics in Elucidating Mitochondrial Metabolic Reprogramming and Therapeutic Targets. (2026/09/01) ♡
- Melatonin Suppresses Osteoclastogenesis via Inhibiting Iron/ROS-CREB/PGC-1β-Mediated Mitochondrial Biogenesis. (2026/09/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Effects of Intravenously Administered Plasma from Exercise-Trained Donors on Mitochondrial Respiration in a Rat Model of Alzheimer's Disease. (2026/09/01) ♡
- ZNF143 suppresses mitophagy to drive MASLD progression by regulating SMURF1/TRPV1 axis. (2026/08/11) ♡
- Molecular response of Tribolium castaneum to benzothiazole: insights from transcriptome and functional validation of UGT2B9. (2026/08/11) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Leptin-cholesterol crosstalk in pregnancy: Mechanistic implications for placental function and cardiometabolic programming. (2026/08/11) ♡
- ABHD11-Mediated mtDNA Transcription Restored Mitochondrial Function to Attenuate Cardiomyocyte Ferroptosis After Myocardial Infarction. (2026/08/11) ♡
- Lead triggers hepatocyte ferroptosis through coordinated mitochondrial injury and ER stress-mediated autophagic degradation of GPX4. (2026/08/10) ♡
- Activation of pro-survival autophagy by a small molecule promoting p62 oligomerisation. (2026/08/10) ♡
- MCART1 (SLC25A51) deficiency exacerbates mitochondrial dysfunction during MPP(+)-induced complex I stress. (2026/08/10) ♡
- Corrigendum to "The ROS/SIRT1/STAR axis as a target for melatonin ameliorating atrazine-induced mitochondrial dysfunction and steroid disorders in granulosa cells" [Ecotoxicol. Environ. Saf. 269 (2024) 115780]. (2026/08/10) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Author Correction: Butyrate extends health and lifespan in mice with mitochondrial deficiency. (2026/08/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging roles of mitophagy in liver fibrosis: Implications for therapy. (2026/08/10) ♡
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