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Mitochondrial diseases

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (34)Meta-analysis (3)Treatment guideline (1)Systematic review (16)Randomized trial (11)Phase 3 study (3)Clinical Trial (599)Overview article (690)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (270)Case Description (79)Commentary or Editorial (11)Retracted Publication (9) Studies currently recruiting participants only (31)

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Publications and studies (3465)

• [Mechanism of Cistanches Herba in treatment of cancer-related fatigue based on network pharmacology and experimental verification]. (2023/03/01) ♡
• Non-negative matrix factorisation of Raman spectra finds common patterns relating to neuromuscular disease across differing equipment configurations, preclinical models and human tissue. (2023/03/01) ♡
• Pathological Sequelae Associated with Skeletal Muscle Atrophy and Histopathology in G93A*SOD1 Mice. (2023/03/01) ♡
• Synergistic anticancer effect of flavonoids from Sophora alopecuroides with Sorafenib against hepatocellular carcinoma. (2023/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanistic study of optic atrophy 1 in ischemia-reperfusion disease. (2023/02/01) ♡
• Sodium tanshinone IIA sulfonate protects against hyperhomocysteine-induced vascular endothelial injury via activation of NNMT/SIRT1-mediated NRF2/HO-1 and Akt/MAPKS signaling in human umbilical vascular endothelial cells. (2023/02/01) ♡
• Ginsenoside Rk3 ameliorates Aβ-induced neurotoxicity in APP/PS1 model mice via AMPK signaling pathway. (2023/02/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Invited review: Assessment of body condition score and body fat reserves in relation to insulin sensitivity and metabolic phenotyping in dairy cows. (2023/02/01) ♡
• Sirtuin 3 relieves inflammatory responses elicited by lipopolysaccharide via the PGC1α-NFκB pathway in bovine mammary epithelial cells. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Mitoquinone mesylate attenuates pathological features of lean and obese allergic asthma in mice. (2023/02/01) ♡
• AdipoRon enhances healthspan in middle-aged obese mice: striking alleviation of myosteatosis and muscle degenerative markers. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The protective effect of erinacin A-enriched Hericium erinaceus mycelium ethanol extract on oxidative stress-induced neurotoxicity in cell and Drosophila models of spinocerebellar ataxia type 3. (2023/02/01) ♡
• Pleiotrophin deficiency protects against high-fat diet-induced neuroinflammation: Implications for brain mitochondrial dysfunction and aberrant protein aggregation. (2023/02/01) ♡
• The impact of high-fat feeding and parking overexpression on skeletal muscle mass, mitochondrial respiration, and H (2) O (2) emission. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Flavonoids from Scutellaria amoena C. H. Wright alleviate mitochondrial dysfunction and regulate oxidative stress via Keap1/nrf2/HO-1 axis in rats with high-fat diet-induced nonalcoholic steatohepatitis. (2023/02/01) ♡
• The effect of isovitexin on lipopolysaccharide-induced renal injury and inflammation by induction of protective autophagy. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Sarcosine (glycine transporter inhibitor) attenuates behavioral and biochemical changes induced by ketamine, in the rat model of schizophrenia. (2023/02/01) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases. (2023/02/01) ♡
• The receptor for advanced glycation end products (RAGE) is involved in mitochondrial function and cigarette smoke-induced oxidative stress. (2023/02/01) ♡
• Caveolin-1 alleviates acetaminophen-induced vascular oxidative stress and inflammation in non-alcoholic fatty liver disease. (2023/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chronic kidney disease-induced muscle atrophy: Molecular mechanisms and promising therapies. (2023/02/01) ♡
• Effects of methionine intake on cognitive function in mild cognitive impairment patients and APP/PS1 Alzheimer's Disease model mice: Role of the cystathionine β synthase/H (2) S pathway. (2023/02/01) ♡
• 5- (4-Hydroxy-3-dimethoxybenzylidene) -thiazolidinone improves motor functions and exerts antioxidant potential in hemiparkinsonian rats. (2023/02/01) ♡
• MicroRNA-27a-3p targets FoxO signalling to induce tumour-like phenotypes in bile duct cells. (2023/02/01) ♡
• Honokiol alleviated neurodegeneration by reducing oxidative stress and improving mitochondrial function in mutant SOD1 cellular and mouse models of amyotrophic lateral sclerosis. (2023/02/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Synergistic activation of AMPK by AdiPoR1/2 agonist and inhibitor of EDPS-EBP interaction recover NAFLD through enhancing mitochondrial function in mice. (2023/02/01) ♡
• PKM2-mediated neuronal hyperglycolysis enhances the risk of Parkinson's disease in diabetic rats. (2023/02/01) ♡
• Jinhua Qinggan granules attenuates acute lung injury by promotion of neutrophil apoptosis and inhibition of TLR4/MyD88/NF-κB pathway. (2023/01/30) ♡
• Piperlongumine overcomes imatinib resistance by inducing proteasome inhibition in chronic myelogenous leukemia cells. (2023/01/30) ♡
• Spectrum of germline and somatic mitochondrial DNA variants in Tuberous Sclerosis Complex. (2023/01/30) ♡
• Engineering zinc oxide hybrid selenium nanoparticles for synergetic anti-tuberculosis treatment by combining Mycobacterium tuberculosis killings and host cell immunological inhibition. (2023/01/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Proteomic profiling reveals the potential mechanisms and regulatory targets of sirtuin 4 in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's mouse model. (2023/01/25) ♡
• Transcranial near-infrared laser improves postoperative neurocognitive disorder in aged mice via SIRT3/AMPK/nrf2 pathway. (2023/01/24) ♡
• Distinct phenotype of neutrophil, monocyte, and eosinophil populations indicates altered myelopoiesis in a subset of patients with multiple myeloma. (2023/01/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case report: Rare novel MIPEP compound heterozygous variants presenting with hypertrophic cardiomyopathy, severe lactic acidosis and hypotonia in a Chinese infant. (2023/01/16) ♡
• Mitochondrial plasticity supports proliferative outgrowth and invasion of ovarian cancer spheroids during adhesion. (2023/01/16) ♡
• Improving human mesenchymal stem cell-derived hepatic cell energy metabolism by manipulating glucose homeostasis and glucocorticoid signaling. (2023/01/13) ♡
• Deep Intronic FGF14 GAA Repeat Expansion in Late-Onset Cerebellar Ataxia. (2023/01/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Protective effect of natural products in metabolic-associated kidney diseases via regulating mitochondrial dysfunction. (2023/01/12) ♡
• Hybrid peptide NTP-217 triggers ROS-mediated rapid necrosis in liver cancer cells by induction of mitochondrial leakage. (2023/01/12) ♡
• Development and validation of a cuproptosis-associated prognostic model for diffuse large B-cell lymphoma. (2023/01/12) ♡
• Brain-enriched miR-128: Reduced in exosomes from Parkinson's patient plasma, improves synaptic integrity, and prevents 6-OHDA mediated neuronal apoptosis. (2023/01/12) ♡
• Alkaloid from Alstonia yunnanensis diels root against gastrointestinal cancer: Acetoxytabernosine inhibits apoptosis in hepatocellular carcinoma cells. (2023/01/11) ♡
• Natural product manoalide promotes EGFR-TKI sensitivity of lung cancer cells by KRAS-ERK pathway and mitochondrial Ca(2+) overload-induced ferroptosis. (2023/01/11) ♡
• Vanadium exposure exacerbates allergic airway inflammation and remodeling through triggering reactive oxidative stress. (2023/01/11) ♡
• A unique insight for Xiaoyao San exerts antidepressant effects by modulating hippocampal glucose catabolism using stable isotope-resolved metabolomics. (2023/01/10) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Lactobacillus plantarum ZJUIDS14 alleviates non-alcoholic fatty liver disease in mice in association with modulation in the gut microbiota. (2023/01/09) ♡
• Gα(q) modulates the energy metabolism of osteoclasts. (2023/01/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Phosphatidylethanolamine homeostasis under conditions of impaired CDP-ethanolamine pathway or phosphatidylserine decarboxylation. (2023/01/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ketogenic Diet for Neonatal Hypoxic-Ischemic Encephalopathy. (2023/01/04) ♡

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