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Mitochondrial diseases

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (34)Meta-analysis (3)Treatment guideline (1)Systematic review (16)Randomized trial (11)Phase 3 study (3)Clinical Trial (599)Overview article (690)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (270)Case Description (79)Commentary or Editorial (11)Retracted Publication (9) Studies currently recruiting participants only (31)

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Publications and studies (3465)

• Fibroblast Growth Factor (FGF) 23 and FGF Receptor 4 promote cardiac metabolic remodeling in chronic kidney disease. (2023/12/23) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dynamin-Related Protein 1 Binding Partners MiD49 and MiD51 Increased Mitochondrial Fission In Vitro and Atherosclerosis in High-Fat-Diet-Fed ApoE(-/-) Mice. (2023/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Climate Stressors and Physiological Dysregulations: Mechanistic Connections to Pathologies. (2023/12/23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Randomised controlled trial combining vitamin E-functionalised chocolate with physical exercise to reduce the risk of protein-energy malnutrition in predementia aged people: study protocol for Choko-Age. (2023/12/22) ♡
• Hyperglycemia-induced STING signaling activation leads to aortic endothelial injury in diabetes. (2023/12/21) ♡
• Astaxanthin Ameliorates Worsened Muscle Dysfunction of MDX Mice Fed with a High-Fat Diet through Reducing Lipotoxicity and Regulating Gut Microbiota. (2023/12/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Mechanisms of Neuroprotection by Ketone Bodies and Ketogenic Diet in Cerebral Ischemia and Neurodegenerative Diseases. (2023/12/21) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. High Sucrose Diet-Induced Subunit I Tyrosine 304 Phosphorylation of Cytochrome c Oxidase Leads to Liver Mitochondrial Respiratory Dysfunction in the Cohen Diabetic Rat Model. (2023/12/21) ♡
• Integrated Bioinformatics and Validation Reveal IFI27 and Its Related Molecules as Potential Identifying Genes in Liver Cirrhosis. (2023/12/21) ♡
• Antiviral Mechanisms of Saucerneol from Saururus chinensis against Enterovirus A71, Coxsackievirus A16, and Coxsackievirus B3: Role of Mitochondrial ROS and the STING/TKB-1/IRF3 Pathway. (2023/12/21) ♡
• Engineered triphenylphosphonium-based, mitochondrial-targeted liposomal drug delivery system facilitates cancer cell killing actions of chemotherapeutics. (2023/12/21) ♡
• Mtfp1 ablation enhances mitochondrial respiration and protects against hepatic steatosis. (2023/12/20) ♡
• The Dynamic SUMOylation Changes and Their Potential Role in the Senescence of APOE4 Mice. (2023/12/20) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Trachyspermum ammi Bioactives Promote Neuroprotection by Inhibiting Acetylcholinesterase, Aβ-Oligomerization/Fibrilization, and Mitigating Oxidative Stress In Vitro. (2023/12/20) ♡
• Emerging role of vitamin D(3) in alleviating intestinal structure injury caused by Aeromonas hydrophila in grass carp (Ctenopharyngodon idella). (2023/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Copper and cuproptosis: new therapeutic approaches for Alzheimer's disease. (2023/12/19) ♡
• Didymin alleviates metabolic dysfunction-associated fatty liver disease (MAFLD) via the stimulation of Sirt1-mediated lipophagy and mitochondrial biogenesis. (2023/12/19) ♡
• Whole blood RNA sequencing identifies transcriptional differences between primary sclerosing cholangitis and ulcerative colitis. (2023/12/19) ♡
• Beyond MitoCarta-expanding the list of candidate proteins involved in mitochondrial functions using a biological network approach. (2023/12/19) ♡
• Elucidating the Influence of MPT-driven necrosis-linked LncRNAs on immunotherapy outcomes, sensitivity to chemotherapy, and mechanisms of cell death in clear cell renal carcinoma. (2023/12/15) ♡
• Hepatocyte steatosis activates macrophage inflammatory response accelerating atherosclerosis development. (2023/12/15) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. VCD-induced menopause mouse model reveals reprogramming of hepatic metabolism. (2023/12/14) ♡
• Astaxanthin Protects against Alcoholic Liver Injury via Regulating Mitochondrial Redox Balance and Calcium Homeostasis. (2023/12/13) ♡
• Genes with epigenetic alterations in human pancreatic islets impact mitochondrial function, insulin secretion, and type 2 diabetes. (2023/12/12) ♡
• Cdc42 deletion yielded enamel defects by disrupting mitochondria and producing reactive oxygen species in dental epithelium. (2023/12/12) ♡
• Association between plasma L-carnitine levels and mitochondrial DNA copy number. (2023/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Thyroid Hormone and Mitochondrial Dysfunction: Therapeutic Implications for Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD). (2023/12/09) ♡
• Identification of key genes associated with heart failure based on bioinformatics analysis and screening of traditional Chinese medicines for the prevention and treatment of heart failure. (2023/12/08) ♡
• A naturally occurring polyacetylene isolated from carrots promotes health and delays signatures of aging. (2023/12/08) ♡
• Fat oxidation rates and cardiorespiratory responses during exercise in different subject populations with post-acute sequelae of SARS-CoV-2 infection: a comparison with normative percentile values. (2023/12/08) ♡
• Mitochondria- and NOX4-dependent antioxidant defense mitigates progression to nonalcoholic steatohepatitis in obesity. (2023/12/07) ♡
• The interplay between sex, time of day, fasting status, and their impact on cardiac mitochondrial structure, function, and dynamics. (2023/12/07) ♡
• Nanocurcumin Reduces High Glucose and Particulate Matter-Induced Endothelial Inflammation: Mitochondrial Function and Involvement of miR-221/222. (2023/12/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Improvement of Intestinal Pseudo-Obstruction by Total Parenteral Nutrition in a Young Woman With Mitochondrial Myopathy, Encephalopathy, Lactic Acidosis, and Stroke-Like Episodes: A Case Report. (2023/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Traditional herbs: mechanisms to combat cellular senescence. (2023/12/05) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Neuromuscular Dysfunction Precedes Cognitive Impairment in a Mouse Model of Alzheimer's Disease. (2023/12/04) ♡
• Leber Hereditary Optic Neuropathy Conversion in a Patient With Idiopathic Intracranial Hypertension. (2023/12/01) ♡
• A combination of isoliquiritigenin with Artemisia argyi and Ohwia caudata water extracts attenuates oxidative stress, inflammation, and apoptosis by modulating Nrf2/Ho-1 signaling pathways in SD rats with doxorubicin-induced acute cardiotoxicity. (2023/12/01) ♡
• A classical herbal formula alleviates high-fat diet induced nonalcoholic steatohepatitis (NASH) via targeting mitophagy to rehabilitate dysfunctional mitochondria, validated by UPLC-HRMS identification combined with in vivo experiment. (2023/12/01) ♡
• Anti-Nasopharyngeal carcinoma mechanism of sanguinarine based on network pharmacology and molecular docking. (2023/12/01) ♡
• Anti-Inflammatory Effects of Chaenomeles sinensis Extract in an ALS Animal Model. (2023/12/01) ♡
• [Improvement effect of Shegan Mahuang Decoction on rats with cold-induced asthma based on TRPV1/NRF-1/mttfa pathway]. (2023/12/01) ♡
• Fecal microbiota transplanted from old mice promotes more colonic inflammation, proliferation, and tumor formation in azoxymethane-treated A/J mice than microbiota originating from young mice. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitophagy in human health, ageing and disease. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Decoding metabolic signatures in Alzheimer's disease: a mitochondrial perspective. (2023/12/01) ♡
• Notch signaling in thyrocytes is essential for adult thyroid function and mammalian homeostasis. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Experimental research progress in traditional Chinese medicine prevention and treatment of diabetic peripheral neuropathy based on autophagy]. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Renal manifestations in adults with mitochondrial disease from the mtDNA m.3243a>g pathogenic variant. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role of Mitochondrial DNA in Yeast Replicative Aging. (2023/12/01) ♡
• Human chemically-derived hepatic progenitors (hCDHS) as a source of liver organoid generation: Application in regenerative medicine, disease modeling, and toxicology testing. (2023/12/01) ♡

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