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Mitochondrial diseases
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Publications and studies (3465)
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Biallelic variants in HTRA2 cause 3-methylglutaconic aciduria mitochondrial disorder: case report and literature review. (2024/01/18) ♡
- Consolidative thoracic radiation therapy for extensive-stage small cell lung cancer in the era of first-line chemoimmunotherapy: preclinical data and a retrospective study in Southern Italy. (2024/01/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Time-restricted ketogenic diet in amyotrophic lateral sclerosis: a case study. (2024/01/18) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Lentiviral gene therapy with IGF2-tagged GAA normalizes the skeletal muscle proteome in murine Pompe disease. (2024/01/16) ♡
- Reduction of inflammation and mitochondrial degeneration in mutant SOD1 mice through inhibition of voltage-gated potassium channel Kv1.3. (2024/01/16) ♡
- Hexokinase-linked glycolytic overload and unscheduled glycolysis in hyperglycemia-induced pathogenesis of insulin resistance, beta-cell glucotoxicity, and diabetic vascular complications. (2024/01/16) ♡
- Luteolin-7-O-glucoside promotes macrophage release of IFN-β by maintaining mitochondrial function and corrects the disorder of glucose metabolism during RSV infection. (2024/01/15) ♡
- Beta-lapachone ameliorates the progression of primary sclerosing cholangitis pathogenesis in rodent models. (2024/01/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Important roles of linoleic acid and α-linolenic acid in regulating cognitive impairment and neuropsychiatric issues in metabolic-related dementia. (2024/01/15) ♡
- Potent in vivo efficacy of oral gallium maltolate in treatment-resistant glioblastoma. (2024/01/15) ♡
- Expanding the genetic spectrum of mitochondrial diseases in Tunisia: novel variants revealed by whole-exome sequencing. (2024/01/12) ♡
- Microbiota affects mitochondria and immune cell infiltrations via alternative polyadenylation during postnatal heart development. (2024/01/12) ♡
- Huzhangqingmaiyin protected vascular endothelial cells against cerebral small vessel disease through inhibiting inflammation. (2024/01/10) ♡
- Study on the neuroprotective effect of Zhimu-Huangbo extract on mitochondrial dysfunction in HT22 cells induced by D-galactose by promoting mitochondrial autophagy. (2024/01/10) ♡
- Low-Se Diet Increased Mitochondrial ROS to Suppress Myoblasts Proliferation and Promote Apoptosis in Broilers via miR-365-3p/SelT Signaling Axis. (2024/01/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A metabolic perspective of the neutrophil life cycle: new avenues in immunometabolism. (2024/01/08) ♡
- Macrophage SREBP1 regulates skeletal muscle regeneration. (2024/01/08) ♡
- Intestinal parasites infecting captive non-human primates in Italy. (2024/01/08) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Have one's view of the important overshadowed by the trivial: chronic progressive external ophthalmoplegia combined with unilateral facial nerve injury: a case report and literature review. (2024/01/05) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial fatty acid synthesis is an emergent central regulator of mammalian oxidative metabolism. (2024/01/02) ♡
- Methods for detection of mitochondrial reactive oxygen species in senescent cells. (2024/01/01) ♡
- Ginsenoside RK1 improves cognitive impairments and pathological changes in Alzheimer's disease via stimulation of the AMPK/Nrf2 signaling pathway. (2024/01/01) ♡
- Erxian Decoction-induced serum exosomes slowed bone marrow mesenchymal stem cell senescence through mitophagy. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Artemisinin protects dopaminergic neurons against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity in a mouse model of Parkinson's disease. (2024/01/01) ♡
- Curcumin-ZnO conjugated nanoparticles confer neuroprotection against ketamine-induced neurotoxicity. (2024/01/01) ♡
- Bi-functional astaxanthin macromolecular nanocarriers to alleviate dextran sodium sulfate-induced inflammatory bowel disease. (2024/01/01) ♡
- Hepatocyte Deubiquitinating Enzyme OTUD5 Deficiency is a Key Aggravator for Metabolic Dysfunction-Associated Steatohepatitis by Disturbing Mitochondrial Homeostasis. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. High-fat diet exacerbated motor dysfunction via necroptosis and neuroinflammation in acrylamide-induced neurotoxicity in mice. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Isoquercitrin attenuates the progression of non-alcoholic steatohepatitis in mice by modulating galectin-3-mediated insulin resistance and lipid metabolism. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. SIRT3 regulates mitochondrial function: A promising star target for cardiovascular disease therapy. (2024/01/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Monocyte transcriptomic profile following EPA and DHA supplementation in men and women with low-grade chronic inflammation. (2024/01/01) ♡
- Multi-omic insight into the molecular networks of mitochondrial dysfunction in the pathogenesis of inflammatory bowel disease. (2024/01/01) ♡
- DON induced DNA damage triggers absence of p53-mediated G2 arrest and apoptosis in IPEC-1 cells. (2024/01/01) ♡
- Mitochondrial dysfunction abrogates dietary lipid processing in enterocytes. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Therapeutic effects of the combination of moderate-intensity endurance training and MitoQ supplementation in rats with isoproterenol-induced myocardial injury: The role of mitochondrial fusion, fission, and mitophagy. (2024/01/01) ♡
- Clinical and genetic keys to cerebellar ataxia due to FGF14 GAA expansions. (2024/01/01) ♡
- NME4 mediates metabolic reprogramming and promotes nonalcoholic fatty liver disease progression. (2024/01/01) ♡
- Estimation of Ambulation and Survival in Neurodegeneration with Brain Iron Accumulation Disorders. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metformin has immunomodulatory effects which support its potential use as adjunctive therapy in tuberculosis. (2024/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Telomerase and mitochondria inhibition promote apoptosis and TET2 and ANMT3a expression in triple negative breast cancer cell lines. (2024/01/01) ♡
- Quercetin protects human coronary artery endothelial cells against hypoxia/reoxygenation-induced mitochondrial apoptosis via the Nrf2/HO-1 axis. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Progress of researches on the role of oxidative stress in acupuncture treatment of Parkinson's disease]. (2024/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuroprotective effects of walnut (Juglans regia L.) in nervous system disorders: A comprehensive review. (2024/01/01) ♡
- The Mitochondrial Targeting Drug SkQ1 Attenuates the Progression of Post-Traumatic Osteoarthritis through Suppression of Mitochondrial Oxidative Stress. (2024/01/01) ♡
- Stimulation of Soluble Guanylyl Cyclase (sGC) by Cinaciguat Attenuates Sepsisinduced Cardiac Injury. (2024/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Hepatocellular Carcinoma Recurrence Surveillance (2024-12-30) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Circulating Tumor Mitochondrial DNA (ct-mtDNA) As a Biomarker for Biliary Tract Cancer Recurrence Surveillance (2024-12-30) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Long-term Extension of Study RP103-MITO-001 (NCT02023866) to Assess Cysteamine Bitartrate Delayed-release Capsules (RP103) in Children With Inherited Mitochondrial Disease (2024-12-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open-Label, Dose-Escalating Study Assessing Safety, Tolerability, Efficacy, of RP103 in Mitochondrial Disease (2024-12-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of High Protein Diet on Hepatic Steatosis in Patients With MAFLD (2024-12-27) ♡
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