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Mitochondrial diseases
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Publications and studies (3465)
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Mechanism of Shenfu injection in suppressing inflammation and preventing sepsis-induced apoptosis in murine cardiomyocytes based on network pharmacology and experimental validation. (2024/03/25) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel Synonymous and Deep Intronic Variants Causing Primary and Secondary Pyruvate Dehydrogenase Complex Deficiency. (2024/03/25) ♡
- Exploring the Interplay between Mitochondrial DNA and Lifestyle Factors in the Pathogenesis of Psychiatric Disorders. (2024/03/20) ♡
- Multi-omics analysis of TLCD1 as a promising biomarker in pan-cancer. (2024/03/15) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Expanding the Phenotypic Spectrum: Chronic Kidney Disease in a Patient with Combined Oxidative Phosphorylation Defect 21. (2024/03/12) ♡
- Nanoplastic propels diet-induced NAFL to NASH via ER-mitochondrial tether-controlled redox switch. (2024/03/05) ♡
- Sequential MFN2-related Optic Neuropathies in a Patient With Serpiginous Choroiditis. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A clinical study and future prospects for bioactive compounds and semi-synthetic molecules in the therapies for Huntington's disease. (2024/03/01) ♡
- Effect and molecular mechanism of Sulforaphane alleviates brain damage caused by acute carbon monoxide poisoning: Network pharmacology analysis, molecular docking, and experimental evidence. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A new direction in Chinese herbal medicine ameliorates for type 2 diabetes mellitus: Focus on the potential of mitochondrial respiratory chain complexes. (2024/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Energy preservation for skeletal muscles: Shenqi Fuzheng injection prevents tissue wasting and restores bioenergetic profiles in a mouse model of chemotherapy-induced cachexia. (2024/03/01) ♡
- How dietary advanced glycation end products could facilitate the occurrence of food allergy. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential regulatory role of PGC-1α within the skeletal muscle during metabolic adaptations in response to high-fat diet feeding in animal models. (2024/03/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Magnetic resonance spectroscopy in MELAS syndrome: correlation with CSF and plasma metabolite levels and change after glutamine supplementation. (2024/03/01) ♡
- Mitofusin-2 induced by exercise modifications lipid droplet mitochondria communication, promoting fatty acid oxidation in male mice with NAFLD. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. AMPK Signaling Pathway as a Potential Therapeutic Target for Parkinson's Disease. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential Applications of Mitochondrial Therapy with a Focus on Parkinson's Disease and Mitochondrial Transplantation. (2024/03/01) ♡
- Altered synaptic currents, mitophagy, mitochondrial dynamics in Alzheimer's disease models and therapeutic potential of Dengzhan Shengmai capsules intervention. (2024/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Premature aging in genetic diseases: what conclusions can be drawn for physiological aging. (2024/02/28) ♡
- Deoxynivalenol induced intestinal barrier injury, mitochondrial dysfunction and calcium overload by inositol 1,4,5-triphosphate receptors (IP3Rs) -mitochondrial calcium uniporter (MCU) calcium axis. (2024/02/25) ♡
- Identifying Acss1, Mtfp1 and Oxct1 as key regulators and promising biomarkers of sarcopenia in various models. (2024/02/20) ♡
- ALDH2 deficiency exacerbates MCD-diet induced MASLD by modulating bile acid metabolism. (2024/02/20) ♡
- Metabolomics analysis to interpret changes in physiological and metabolic responses to chronic heat stress in Pekin ducks. (2024/02/20) ♡
- Jingfang Granule mitigates Coxsackievirus B3-induced myocardial damage by modulating mucolipin 1 expression. (2024/02/10) ♡
- Clinical, neurophysiological evaluation and genetic features of axonal Charcot-Marie-Tooth disease in a Chinese family. (2024/02/02) ♡
- Cardiac energy metabolism disorder mediated by energy substrate imbalance and mitochondrial damage upon tebuconazole exposure. (2024/02/01) ♡
- Electroacupuncture pretreatment preserves telomerase reverse transcriptase function and alleviates postoperative cognitive dysfunction by suppressing oxidative stress and neuroinflammation in aged mice. (2024/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Seladelpar combined with complementary therapies improves fibrosis, inflammation, and liver injury in a mouse model of nonalcoholic steatohepatitis. (2024/02/01) ♡
- Endurance exercise training changes the limitation on muscle V̇O2max in normoxia from the capacity to utilize O (2) to the capacity to transport O (2). (2024/02/01) ♡
- How did antibiotic growth promoters increase growth and feed efficiency in poultry? (2024/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Obesity worsens mitochondrial quality control and does not protect against skeletal muscle wasting in murine cancer cachexia. (2024/02/01) ♡
- Lifelong dietary protein restriction accelerates skeletal muscle loss and reduces muscle fiber size by impairing proteostasis and mitochondrial homeostasis. (2024/02/01) ♡
- Blockade of angiotensin II modulates insulin-like growth factor 1-mediated skeletal muscle homeostasis in experimental steatohepatitis. (2024/02/01) ♡
- MCL attenuates atherosclerosis by suppressing macrophage ferroptosis via targeting KEAP1/NRF2 interaction. (2024/02/01) ♡
- Generation of inducible mitophagy mice. (2024/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Considerations for liver transplantation in deoxyguanosine kinase deficiency: A case series and review of the literature. (2024/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. SGLT2 inhibitor improves kidney function and morphology by regulating renal metabolism in mice with diabetic kidney disease. (2024/02/01) ♡
- Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting DRP1 filamin complex formation. (2024/02/01) ♡
- Multiple species of canine Rhipicephalus complex detected in Canada. (2024/02/01) ♡
- Taxonomy, biological characterization and fungicidal sensitivity assays of Hypomyces cornea sp. nov. causing cobweb disease on Auricularia cornea. (2024/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Update on the diagnosis and management of neonatal intrahepatic cholestasis caused by citrin deficiency: Expert review on behalf of the Asian Pan-Pacific Society for Pediatric Gastroenterology, Hepatology, and Nutrition. (2024/02/01) ♡
- Mapping the metabolic responses to oxaliplatin-based chemotherapy with in vivo spatiotemporal metabolomics. (2024/02/01) ♡
- Isomaculosidine facilitates NLRP3 inflammasome activation by promoting mitochondrial reactive oxygen species production and causes idiosyncratic liver injury. (2024/01/30) ♡
- Morphological, phylogenetic, and genomic evidence reveals the causal agent of thread blight disease of cocoa in Peru is a new species of Marasmius in the section Neosessiles, Marasmius infestans sp. nov. (2024/01/29) ♡
- Fumarate respiration of Fasciola flukes as a potential drug target. (2024/01/25) ♡
- Exploring a novel seven-gene marker and mitochondrial gene TMEM38A for predicting cervical cancer radiotherapy sensitivity using machine learning algorithms. (2024/01/24) ♡
- Blood Monocyte Phenotype Is A Marker of Cardiovascular Risk in Type 2 Diabetes. (2024/01/19) ♡
- Mitofusin-2 Regulates Platelet Mitochondria and Function. (2024/01/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial transfer - a novel promising approach for the treatment of metabolic diseases. (2024/01/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Glucagon-like peptide-1 receptor agonists for the management of diabetic peripheral neuropathy. (2024/01/19) ♡
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