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Mitochondrial diseases
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Publications and studies (3465)
- Clinopodium gracile Alleviates Metabolic Dysfunction-Associated Steatotic Liver Disease by Upregulating Peroxisome Proliferator-Activated Receptor α and Inhibiting Mitochondrial Oxidative Damage. (2024/09/20) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Primary cilia in Parkinson's disease: summative roles in signaling pathways, genes, defective mitochondrial function, and substantia nigra dopaminergic neurons. (2024/09/18) ♡
- Meldonium-induced steatosis is associated with increased delta 6 desaturation and reduced elongation of n-6 polyunsaturated fatty acids. (2024/09/04) ♡
- A liver-fat crosstalk for iron flux during healthy growth of adipose tissue. (2024/09/04) ♡
- Differential roles for the oxygen sensing enzymes PHD1 and PHD3 in the regulation of neutrophil metabolism and function. (2024/09/02) ♡
- Amelioration of gold nanoparticles mediated through Ocimum oil extracts induces reactive oxygen species and mitochondrial instability against MCF-7 breast carcinoma. (2024/09/02) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Resveratrol: potential application in safeguarding testicular health. (2024/09/02) ♡
- Zishenhuoxue decoction-induced myocardial protection against ischemic injury through TMBIM6-VDAC1-mediated regulation of calcium homeostasis and mitochondrial quality surveillance. (2024/09/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Electroacupuncture activates AMPKα1 to improve learning and memory in the APP/PS1 mouse model of early Alzheimer's disease by regulating hippocampal mitochondrial dynamics. (2024/09/01) ♡
- Buzhong Yiqi decoction attenuates acquired myasthenia by regulating the JAK2/STAT3/AKT signaling pathway, inhibiting inflammation, and improving mitochondrial function. (2024/09/01) ♡
- Rehmanniae Radix Praeparata aqueous extract improves hepatic ischemia/reperfusion injury by restoring intracellular iron homeostasis. (2024/09/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Hypertension and obesity independently drive hypertrophy and alter mitochondrial metabolism in a mouse model of heart failure with preserved ejection fraction. (2024/09/01) ♡
- Effective-Component Compatibility of Bufei Yishen Formula III Suppresses Mitochondrial Oxidative Damage in COPD: Via Pkm2/Nrf2 Pathway. (2024/08/24) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Cinnamaldehyde potentiates cytotoxic and apoptogenic effects of doxorubicin in prostate cancer cell line. (2024/08/19) ♡
- Bioinformatic analysis of hippocampal histopathology in Alzheimer's disease and the therapeutic effects of active components of traditional Chinese medicine. (2024/08/16) ♡
- UPF1 deficiency enhances mitochondrial ROS which promotes an immunosuppressive microenvironment in pancreatic ductal adenocarcinoma. (2024/08/13) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Mitochondrial genome copy number variation across tissues in mice and humans. (2024/08/13) ♡
- Platycodon grandiflorum exhibits anti-neuroinflammatory potential against beta-amyloid-induced toxicity in microglia cells. (2024/08/07) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mesenchymal stem cells as a future treatment for cardiovascular regeneration and its challenges. (2024/08/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Potential pathways for traditional Chinese medicine intervention in diabetic kidney disease: macrophage polarization]. (2024/08/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Ultrafiltration of Angelicae Sinensis Radix and Astragali Radix inhibits ferroptosis and improves pulmonary fibrosis in rats by regulating NRF2/XCT/GPX4 signaling pathway]. (2024/08/01) ♡
- Antioxidative Potential and Activity of Potassium Polyacrylate and Coenzyme Q10 on Rat Hepatic Mitochondrial Permeability Transition Pores. (2024/08/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial protective potential of fucoxanthin in brain disorders. (2024/07/25) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Whole exome sequencing in energy deficiency inborn errors of metabolism: A systematic review. (2024/07/13) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Evidence of mitochondria origin of SARS-CoV-2 double-membrane vesicles: a review. (2024/07/10) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Transcription factors, metabolic dysfunction-associated fatty liver disease, and therapeutic implications. (2024/07/05) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Neural stem cell-derived exosomes promote mitochondrial biogenesis and restore abnormal protein distribution in a mouse model of Alzheimer's disease. (2024/07/01) ♡
- Amelioration of Amyloid-β Induced Alzheimer's Disease by Bacopa monnieri through Modulation of Mitochondrial Dysfunction and GSK-3β/WNT/β-Catenin Signaling. (2024/07/01) ♡
- Continuous Optimization of a Hierarchical Bayesian Network for Friedreich's Ataxia Severity Classification. (2024/07/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Insulin Resistance in Pediatric Obesity: From Mechanisms to Treatment Strategies. (2024/06/28) ♡
- Biallelic Recessive Mutations in TLE6 and NLRP5 Cause Female Infertility Characterized by Human Early Embryonic Arrest. (2024/06/22) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Extranuclear DNA Variations in the Susceptibility of Glaucoma (2024/06/14) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Exploring the role and mechanism of hyperoside against cardiomyocyte injury in mice with myocardial infarction based on JAK2/STAT3 signaling pathway. (2024/06/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Atypical Late-Onset Leber Hereditary Optic Neuropathy (LHON) Associated With T14484C Mutation. (2024/06/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel Mutations in the ND5 Gene Associated With Leber Hereditary Optic Neuropathy. (2024/06/01) ♡
- Mitochondrial phosphate carrier plays an important role in the virulence of Candida albicans. (2024/05/16) ♡
- Rapid molecular species identification of mammalian scat samples using nanopore adaptive sampling. (2024/05/06) ♡
- Guanxin V alleviates ventricular remodeling after acute myocardial infarction with circadian disruption by regulating mitochondrial dynamics. (2024/05/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Dose-response effect of pre-exercise carbohydrates under muscle glycogen unavailability: Insights from McArdle disease. (2024/05/01) ♡
- Cellular and mitochondrial adaptation mechanisms in the colon of lactating dairy cows during hyperthermia. (2024/05/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A novel homozygous nonsense variant of AK7 is associated with multiple morphological abnormalities of the sperm flagella. (2024/05/01) ♡
- Gynura divaricata (L.) DC. promotes diabetic wound healing by activating Nrf2 signaling in diabetic rats. (2024/04/06) ♡
- Danggui Buxue Tang improves therapeutic efficacy of doxorubicin in triple negative breast cancer via ferroptosis. (2024/04/06) ♡
- Defecation after magnesium supplementation enhances cognitive performance in triathletes. (2024/04/04) ♡
- Quercetin: A promising therapy for diabetic encephalopathy through inhibition of hippocampal ferroptosis. (2024/04/01) ♡
- Quercetin counteracts monosodium glutamate to mitigate immunosuppression in the thymus and spleen via redox-guided cellular signaling. (2024/04/01) ♡
- Tumor microenvironment-activatable nanocatalysts with chemodynamic therapy and enhanced autophagy for specific treatment of oral squamous cell carcinoma. (2024/04/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Nrf2 activator Diethyl Maleate attenuates ROS mediated NLRP3 inflammasome activation in murine microglia. (2024/04/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Primary Coenzyme Q10 Deficiency-4 Causing Young Onset Ataxia Dystonia. (2024/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Research progress on the toxicity of toxic Traditional Herbals from Thymelaeaceae. (2024/03/25) ♡
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