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Mitochondrial diseases
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Publications and studies (3448)
- Polygonatum sibirsk polysaccharide ameliorates skeletal muscle aging and mitochondrial dysfunction via PI3K/Akt/mTOR signaling pathway. (2025/01/01) ♡
- Xinkeshu formula restrains pathological cardiac hypertrophy through metabolic remodeling via AMPK/mTOR pathway. (2025/01/01) ♡
- Gastrodin: Modulating the XCT/GPx4 and ACSL4/LPCAT3 pathways to inhibit ferroptosis after ischemic stroke. (2025/01/01) ♡
- Nicotinamide riboside targets mitochondrial unfolded protein response to reduce alcohol-induced damage in Kupffer cells. (2025/01/01) ♡
- N-Acetylcysteine enhances low-dose estrogen efficacy against ischemia-reperfusion injury in estrogen-deprived obese insulin-resistant rats. (2025/01/01) ♡
- Augmenter of Liver Regeneration Crotonylation Assists in Mitochondria-ER Contact to Alleviate Hepatic Steatosis. (2025/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Chronic inorganic nitrate supplementation does not improve metabolic health and worsens disease progression in mice with diet-induced obesity. (2025/01/01) ♡
- METTL16 controls airway inflammations in smoking-induced COPD via regulating glutamine metabolism. (2025/01/01) ♡
- Wolfberry Honey and Its Extract Alleviate Dextran Sodium Sulfate-Induced Ulcerative Colitis by Improving Intestinal Barrier Function and Reducing Oxidative Stress and Inflammation. (2025/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Immunology and treatments of fatty liver disease. (2025/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Oxidative stress and inflammation in the pathogenesis of neurological disorders: Mechanisms and implications. (2025/01/01) ♡
- Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila. (2025/01/01) ♡
- Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis (2025/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Small molecule-mediated therapeutic approaches to target Tau and Alzheimer's disease. (2025/01/01) ♡
- Is polyphagy of a specific cryptic Bemisia tabaci species driving the high whitefly populations on cassava in eastern Africa? (2025/01/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Assessment of carbacetam effect on the mitochondria of hippocampal neurons in rats of different sexes with experimental metabolic syndrome. (2025/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The impact of intermittent fasting on cognitive function and neuroprotection: A literature review. (2025/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Bioactive compounds with adjuvant therapeutic potential in neurodegenerative diseases and peripheral neuropathy. (2025/01/01) ♡
- Chlorogenic acid supplementation regulates redox status, hepatic inflammation, and mitochondrial function in weaned piglets with intrauterine growth retardation. (2025/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gene Therapy for Cardiomyopathy Associated With Friedreich's Ataxia (2025-12-23) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Safety Study for Previously Treated Vatiquinone (PTC743) Participants With Inherited Mitochondrial Disease (2025-12-22) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondrial DNA Signatures of Poor Aerobic Exercise Trainability in Young Adults Born Preterm (2025-12-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pilot Study of the Efficacy of Nicotinamide (Vitamin B3) in Leber's Hereditary Optic Neuropathy (2025-12-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Safety of Different Dosages of Mexidol® in Patients With Primary Open-angle Glaucoma (POAG) (2025-12-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. MEXIDOL® Sequential Therapy of Patients with Primary Open-angle Glaucoma (POAG) (2025-12-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. FRDA Investigator Initiated Study (IIS) With Elamipretide (2025-12-12) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mechanisms and Treatment of Exercise Intolerance and Persistent Fatigue in Spinal Muscular Atrophy (2025-12-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Treprostinil to Treat Interstitial Lung Disease Pulmonary Hypertension (2025-12-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. N-DOSE AD: A Dose Optimization Trial of Nicotinamide Riboside in Alzheimer's Disease (2025-12-01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of ASP2016 in Adults Who Have Heart Disease Associated With Friedreich Ataxia (2025-11-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Reference Values of Intraepidermal Nerve Fiber Density in Children and Small Fiber Neuropathy in Neurodevelopmental Disorders (2025-11-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Atypical Antipsychotic-Induced Mitochondrial Dysfunction in Patients With Schizophrenia (2025-11-25) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. New Non-invasive Modalities for Assessing Retinal Structure and Function (2025-11-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Probing the Role of Mitochondrial Oxidative Stress in Impaired Vascular Function Among Young Adults With Early Life Adversity (2025-11-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Innsbruck Health Promotion Program (2025-11-19) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Metabolomics Analysis According to the Retinal Nerve Fiber Layer in Patients With NOHL Mutations (MetaBOCT) (2025-11-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Applying PGz in Mitochondrial Disease (2025-11-10) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Respiratory Training in Friedreich's Ataxia (2025-11-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natural History of Pearson Syndrome (2025-11-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess the Safety and Efficacy of Vatiquinone in Participants With Friedreich Ataxia (2025-10-30) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Role of ROS and cAMP-PKA Biomarkers in ADPKD (2025-10-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate Efficacy and Safety of Elamipretide in Subjects With Primary Mitochondrial Disease From Nuclear DNA Mutations (nPMD) (2025-10-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Testosterone and Long Pulse Stimulation After SCI (2025-10-14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Hepatic Mitochondrial Function in Youth (2025-10-10) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prevent Cardiac Surgery Associated AKI Trial (2025-10-08) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Early Diagnosis of Primary Biliary Cholangitis (PBC) in Patients With Positive Anti-Mitochondrial Antibodies (AMA) and Normal Alkaline Phosphatase (ALP) (2025-10-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Patient Registry of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) (2025-10-03) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Impact of Mitochondrial Dysfunction on Human Bone Cell Metabolism and Remodeling (2025-10-02) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate the MNV-201 in Patients With Low Risk MDS (2025-10-01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Collection of Blood and Skin Samples From Patients With Primary Mitochondrial Diseases and Healthy Volunteers (2025-10-01) ♡
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