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ALS (amyotrophic lateral sclerosis)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the heaviest evidence (99)Meta-analysis (26)Treatment guideline (4)Systematic review (40)Phase 3 Study (15)Randomized trial (14)Clinical trial (625)Review article (535)Early study (phase 1 or 2) (12)Single patient description (77)Laboratory or animal research (69)Commentary or editorial (40)Retracted publication (1) Studies currently recruiting participants only (31)

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Publications and studies (2470)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Adolescent-onset multisystem proteinopathy due to a novel VCP variant. (2024/01/01) ♡
• Nicotinamide riboside, pterostilbene and ibudilast protect motor neurons and extend survival in ALS mice. (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mitochondrial dysfunction in neurodegenerative disorders. (2024/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. A comparison study of pathological features and drug efficacy between Drosophila models of C9orf72 ALS/FTD. (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Phytochemicals as Substances that Affect Astrogliosis and their Implications for the Management of Neurodegenerative Diseases. (2024/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Appendectomy and the risk of neurodegenerative diseases: A two-sample Mendelian randomization study. (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Effects of Red ginseng on neuroinflammation in neurodegenerative diseases. (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Insights on Natural Products Against Amyotrophic Lateral Sclerosis (ALS). (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mycotoxins and Amyotrophic Lateral Sclerosis: Food Exposure, Nutritional Implications and Dietary Solutions. (2024/01/01) ♡
• A prospective study for using cognitive decline as a predictor for survival and use of feeding/respiratory support for patients with motor neuron disease in Norway. (2024/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Coffee and amyotrophic lateral sclerosis (ALS). (2024/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of ZYIL1 in Patients With Amyotrophic Lateral Sclerosis (2024-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases (2024-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Proteinopathies Expression in Skin of Neurodegenerative Disorders (2024-12-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy of Ranolazine for the Treatment of Amyotrophic Lateral Sclerosis (2024-12-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate the Efficacy and Safety of Reldesemtiv in Patients With Amyotrophic Lateral Sclerosis (ALS) (2024-12-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase 1, SAD and MAD Study to Evaluate the Safety and Tolerability of FB418 (2024-12-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Anticipated Patient and Caregiver Burden (2024-11-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Geometrical Facial Deformation According to Posture in Amyotrophic Lateral Sclerosis (2024-11-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tofacitinib in Patients With Amyotrophic Lateral Sclerosis (2024-11-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. FLOWER: Following Longitudinal Outcomes With Epidemiology for Rare Diseases (2024-11-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Home-based Remote Digital Monitoring to Assess ALS Progression (Track ALS) (2024-11-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Testing Pulse Stimulation to Improve Motor Function in People With ALS: A Pilot Study (2024-11-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Polish Version Fatigue Severity Scale (2024-11-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluate the Safety of Neuronata-R® Inj. Suspended With HypoTHermosol® FRS (HTS-FRS) in Patients With ALS (2024-11-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Quest to Analyze One Thousand Humans Meditating (2024-11-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Exploring Nasal Drop Therapy With Small Extracellular Vesicles for ALS (2024-10-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Prospective Study to Evaluate the Correlation Between Oculometric Measurements and Clinical Endpoints in ALS Patients (2024-10-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Validation Study (2024-10-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Edinburgh Cognitive and Behavioural Amyotrophic Lateral Sclerosis Screen in Norway: A Prospective Cohort Study (2024-10-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An IIT Clinical Study to Evaluate the Safety, Tolerability, and Preliminary Efficacy of a Single Intrathecal Injection of SNUG01 in Patients with Amyotrophic Lateral Sclerosis (2024-10-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Contralateral R1 in Amyotrophic Lateral Sclerosis (2024-10-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of [11C]CPPC to Assess the Safety and Tolerability in Patients With ALS (2024-10-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Biomarker Study to Evaluate MN-166 in Subjects With Amyotrophic Lateral Sclerosis (ALS) (2024-09-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Retrospective Study on the Safety and Therapeutic/Improvement Effects of Intravenous Administration of SHED-CM for ALS (SHED-CAH2023) (2024-09-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Neurodegenerative Diseases Progression Markers (MARKERS-NDD) (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Genetic Study of Familial and Sporadic ALS/Motor Neuron Disease, Miyoshi Myopathy and Other Neuromuscular Disorders (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Quality of Life Evaluation with the SRI Questionnaire of ALS Patient with Non-invasive Ventilation (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Rapamycin Treatment for ALS (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Determine the Safety, Pharmacokinetics, and Pharmacodynamics of DNL343 in Participants With Amyotrophic Lateral Sclerosis (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Quantitative and Repetitive TMS in ALS - Recruiting for Stage 2 (2024-09-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fecal Microbiota Transplantation Effect on Amyotrophic Lateral Sclerosis Patients (2024-08-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. MRG-001 in Patients With Amyotrophic Lateral Sclerosis (2024-08-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Emotion Processing Among Patients With ALS (2024-08-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase III Trial of AMX0035 for Amyotrophic Lateral Sclerosis Treatment (2024-08-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase 3, Open-Label Extension of COURAGE-ALS (CY 5031) (2024-08-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Reinnervation and Neuromuscular Transmission in ALS (2024-08-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gait Patterns in Dual-task Conditions in Patients With Amyotrophic Lateral Sclerosis (2024-08-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Magnetic Imaging for Diagnostic of Amyotrophic Lateral Sclerosis (2024-08-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. SOD1 Kinetics Measurements in ALS Patients (2024-07-25) ♡

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