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Duchenne muscular dystrophy

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (36)Meta-analysis (9)Randomized trial (11)Systematic review (9)Phase 3 study (7)Clinical examination (506)Review article (205)Early study (phase 1 or 2) (27)Case report (101)Laboratory or animal study (64)Commentary or editorial (52)Retracted Publication (4) Studies Currently Seeking Participants Only (38)

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Publications (1249)

• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Muscle MRI: A biomarker of disease severity in Duchenne muscular dystrophy? A systematic review. (2020/01/21) ♡
• Blockade of IGF2R improves muscle regeneration and ameliorates Duchenne muscular dystrophy. (2020/01/09) ♡
• The use of the gait profile score and gait variable score in individuals with Duchenne Muscular Dystrophy. (2020/01/02) ♡
• How the central domain of dystrophin acts to bridge F-actin to sarcolemmal lipids. (2020/01/01) ♡
• Presence of metalloproteinases 2 and 9 and 8-OHdG in the fibrotic process in skeletal muscle of Mdx mice. (2020/01/01) ♡
• Cultured hippocampal neurons of dystrophic mdx mice respond differently from those of wild type mice to an acute treatment with corticosterone. (2020/01/01) ♡
• Total Absence of Dystrophin Expression Exacerbates Ectopic Myofiber Calcification and Fibrosis and Alters Macrophage Infiltration Patterns. (2020/01/01) ♡
• Characterisation of utrophin modulator SMT C1100 as a non-competitive inhibitor of firefly luciferase. (2020/01/01) ♡
• Intramuscular blood flow in Duchenne and Becker Muscular Dystrophy: Quantitative power Doppler sonography relates to disease severity. (2020/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Proteomic and cell biological profiling of the renal phenotype of the mdx-4cv mouse model of Duchenne muscular dystrophy. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Reprogramming of human Peripheral Blood Mononuclear Cell (PBMC) from a Chinese patient suffering Duchenne muscular dystrophy to iPSC line (SDQLCHi007-A) carrying deletion of 49-50 exons in the DMD gene. (2020/01/01) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Long-term data with idebenone on respiratory function outcomes in patients with Duchenne muscular dystrophy. (2020/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case Study With Symbihand: An sEMG-Controlled Electrohydraulic Hand Orthosis for Individuals With Duchenne Muscular Dystrophy. (2020/01/01) ♡
• Evaluation of speed-accuracy trade-off in a computer task to identify motor difficulties in individuals with Duchenne Muscular Dystrophy - A cross-sectional study. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Electrical impedance myography for reducing sample size in Duchenne muscular dystrophy trials. (2020/01/01) ♡
• Assessing Physical Activity Using Accelerometers in Youth with Duchenne Muscular Dystrophy. (2020/01/01) ♡
• Enhanced Methods for Needle Biopsy and Cryopreservation of Skeletal Muscle in Older Adults. (2020/01/01) ♡
• Outcomes of Zoledronic Acid Use in Paediatric Conditions. (2020/01/01) ♡
• T cell receptor specificity drives accumulation of a reparative population of regulatory T cells within acutely injured skeletal muscle. (2019/12/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy. (2019/12/26) ♡
• S-nitrosylation of connexin43 hemichannels elicits cardiac stress-induced arrhythmias in Duchenne muscular dystrophy mice. (2019/12/19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pulsed glucocorticoids enhance dystrophic muscle performance through epigenetic-metabolic reprogramming. (2019/12/19) ♡
• An improved method for studying mouse diaphragm function. (2019/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. S1P/S1P Receptor Signaling in Neuromuscular Disorders. (2019/12/17) ♡
• Use of air stacking to improve pulmonary function in Indonesian Duchenne muscular dystrophy patients: bridging the standard of care gap in low middle income country setting. (2019/12/16) ♡
• Development of a high-throughput screen to identify small molecule enhancers of sarcospan for the treatment of Duchenne muscular dystrophy. (2019/12/12) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. In vivo cerebellar circuit function is disrupted in an mdx mouse model of Duchenne muscular dystrophy. (2019/12/09) ♡
• Exploring physiological signals on people with Duchenne muscular dystrophy for an active trunk support: a case study. (2019/12/09) ♡
• Targeting RyR Activity Boosts Antisense Exon 44 and 45 Skipping in Human DMD Skeletal or Cardiac Muscle Culture Models. (2019/12/06) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Strength training and aerobic exercise training for muscle disease. (2019/12/06) ♡
• CRISPR-Cas3 induces broad and unidirectional genome editing in human cells. (2019/12/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Recurrent hypotension induced by sacubitril/valsartan in cardiomyopathy secondary to Duchenne muscular dystrophy: A case report. (2019/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolic Alterations in Cardiomyocytes of Patients with Duchenne and Becker Muscular Dystrophies. (2019/12/05) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Characterization of mesoangioblast cell fate and improved promyogenic potential of a satellite cell-like subpopulation upon transplantation in dystrophic murine muscles. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Importance of muscle biopsy to establish pathogenicity of DMD missense and splice variants. (2019/12/01) ♡
• Psychiatric and neurodevelopmental aspects of Becker muscular dystrophy. (2019/12/01) ♡
• Evaluation of gait in Duchenne Muscular Dystrophy: Relation of 3D gait analysis to clinical assessment. (2019/12/01) ♡
• Detection of collagens by multispectral optoacoustic tomography as an imaging biomarker for Duchenne muscular dystrophy. (2019/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Dystrophinopathies. (2019/12/01) ♡
• The NIH Toolbox for cognitive surveillance in Duchenne muscular dystrophy. (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Gene Therapy Briefs. (2019/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Muscular dystrophies. (2019/11/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Teaching an Old Molecule New Tricks: Drug Repositioning for Duchenne Muscular Dystrophy. (2019/11/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. QuantiMus: A Machine Learning-Based Approach for High Precision Analysis of Skeletal Muscle Morphology. (2019/11/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Biomaterials and Advanced Biofabrication Techniques in hiPSCs Based Neuromyopathic Disease Modeling. (2019/11/29) ♡
• Micro-dystrophin Gene Therapy Partially Enhances Exercise Capacity in Older Adult mdx Mice. (2019/11/27) ♡
• N-acetylcysteine Decreases Fibrosis and Increases Force-Generating Capacity of mdx Diaphragm. (2019/11/24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tamoxifen in Duchenne muscular dystrophy (TAMDMD): study protocol for a multicenter, randomized, placebo-controlled, double-blind phase 3 trial. (2019/11/21) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Transcriptomic Analysis Reveals Involvement of the Macrophage Migration Inhibitory Factor Gene Network in Duchenne Muscular Dystrophy. (2019/11/18) ♡
• Becker muscular dystrophy caused by exon 2-truncating mutation of DMD. (2019/11/18) ♡

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