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Thalassemia (severe form)
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Publications and studies (1521)
- A rapid quantification method for the screening indicator for β-thalassemia with near-infrared spectroscopy. (2018/03/15) ♡
- Combined iron chelator and T-type calcium channel blocker exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice. (2018/03/05) ♡
- Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase II, Multicenter, Single-Arm Study to Evaluate the Safety and Efficacy of Deferasirox after Hematopoietic Stem Cell Transplantation in Children with β-Thalassemia Major. (2018/03/01) ♡
- Effect of iron overload on impaired fertility in male patients with transfusion-dependent beta-thalassemia. (2018/03/01) ♡
- Prevalence of sickle cell disease among Grenadian newborns. (2018/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies. (2018/03/01) ♡
- A long noncoding RNA from the HBS1L-MYB intergenic region on chr6q23 regulates human fetal hemoglobin expression. (2018/03/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Iron-chelating effect of silymarin in patients with β-thalassemia major: A crossover randomised control trial. (2018/03/01) ♡
- Decisional conflict and regret: shared decision-making about pregnancy affected by β-thalassemia major in Southeast of Iran. (2018/03/01) ♡
- No Association of Genetic Markers with Carotid Intimal Medial Thickness in β-Thalassemia Major Patients. (2018/03/01) ♡
- Safety and Efficacy of Sofosbuvir and Daclatasvir for Hepatitis C Virus Infection in Patients with β-Thalassemia Major. (2018/03/01) ♡
- Distribution of hemoglobinopathy disorders in Saudi Arabia based on data from the premarital screening and genetic counseling program, 2011-2015. (2018/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A contemporary therapeutic approach to bone disease in beta-thalassemia - a review. (2018/03/01) ♡
- Factor V Leiden G1691A, Prothrombin G20210A, and MTHFR C677T and A1298C Mutations in Patients With Sickle Cell Disease in Tunisia. (2018/03/01) ♡
- Liver fibrosis alleviation after co-transplantation of hematopoietic stem cells with mesenchymal stem cells in patients with thalassemia major. (2018/02/01) ♡
- Management of patients with major beta thalassemia in a paediatric department in the south of Tunisia: About 26 cases. (2018/02/01) ♡
- Calibration by commutable control materials is able to reduce inter-method differences of current high-performance methods for HbA(2). (2018/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Clinical relevance of deferasirox trough levels in β-thalassemia patients. (2018/02/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Financial Burden of Treatment of Transfusion Dependent Thalassemia. (2018/02/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical outcomes of unrelated cord blood transplantation in children with malignant and non-malignant diseases: Multicenter experience in China. (2018/02/01) ♡
- A strategy for the clinical remission of acute lymphoblastic leukemia elicited by treatment of β-thalassemia major: A case report. (2018/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model. (2018/01/11) ♡
- Double heterozygocity for hemoglobin C and beta thalassemia dominant: A rare case of thalassemia intermedia. (2018/01/03) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Iron and infection. (2018/01/01) ♡
- The intrinsic genetic and epigenetic regulator factors as therapeutic targets, and the effect on fetal globin gene expression. (2018/01/01) ♡
- A Universal Approach to Correct Various HBB Gene Mutations in Human Stem Cells for Gene Therapy of Beta-Thalassemia and Sickle Cell Disease. (2018/01/01) ♡
- Oral manifestations and dentofacial anomalies in β-thalassemia major children in Dubai (UAE). (2018/01/01) ♡
- KLF1 gene and borderline hemoglobin A(2) in Saudi population. (2018/01/01) ♡
- C-Window Peaks on CE-HPLC are Extremely Rare in Northern India, and Only Infrequently Represent HbC. (2018/01/01) ♡
- Diagnosis of Compound Heterozygous Hb Tak/β-Thalassemia and HbD-Punjab/β-Thalassemia by HbA(2) Levels on Capillary Electrophoresis. (2018/01/01) ♡
- Fractures and Low Bone Mineral Density in Patients with Beta Thalassemia Major. (2018/01/01) ♡
- A Compound Heterozygous Asian Indian Inversion Deletion Gγ(Aγδβ)(0) with β-Thalassemia in Central India: A Case Report. (2018/01/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Compound heterozygote of Hb D(Iran) [HBB: c.67G>C, β 22(B4) Glu>Gln] with β(0)-thalassemia [cds 41/42 (-CTTT)] from Eastern India. (2018/01/01) ♡
- A combination of an iron chelator with an antioxidant exerts greater efficacy on cardioprotection than monotherapy in iron-overload thalassemic mice. (2018/01/01) ♡
- Summary and Review of the Abstracts on Disorders of Red Cells and Erythropoiesis Presented at Haematocon 2016-2017. (2018/01/01) ♡
- Thalassemia and other hemoglobinopathies among anemic individuals in Metro Manila, Philippines and their intake of iron supplements. (2018/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Association of Serum Vitamin D Level with its Receptor Gene Polymorphism BSML in Beta Thalassemia Major Patients from East India. (2018/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Efficacy and Safety of Sugammadex in Children 0-2 Years Old (2018-11-02) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Decision Aid for Therapeutic Options In Sickle Cell Disease (2018-10-09) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Bitopertin (RO4917838) in Adults With Non-Transfusion-Dependent (NTD) Beta-Thalassemia (2018-10-05) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of Spirulina on Cardiac Functions in Children With Beta Thalassemia Major (2018-09-11) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Spirulina on Liver Fibrosis by Transient Elastography in Beta Thalassemic Children With Hepatitis C (2018-09-11) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Spirulina on Liver Iron Concentration in Beta Thalassemic Children With Hepatitis C (2018-09-11) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Monitoring of Chimerism After Transplantation in Patients With β Thalassemia Major and the Treatment Strategies for the Reduction of Chimerism (2018-08-28) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. L-arginine Versus Sildenafil in Children With Beta Thalassemia Associated With Pulmonary Hypertension (2018-08-27) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. CD34+Selection for Partially Matched Family or Matched Unrelated Adult Donor Transplant (2018-08-21) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Use of CGMS to Detect Alterations of Blood Glucose in Thalassemic Patients (2018-07-19) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate Efficacy and Safety of S303 Treated Red Blood Cells (RBCs)in Subjects With Thalassemia Major Requiring Chronic RBC Transfusion (2018-07-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Potential Hepatoprotective Effect of Metformin in Patients With Beta Thalassemia Major (2018-07-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Spirulina Compared to Amlodipine on Cardiac Iron Overload in Children With Beta Thalassemia (2018-07-12) ♡
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