← All diseases Blood and bone marrow

Thalassemia (severe form)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (54)Meta-analysis (12)Treatment guideline (1)Randomized trial (20)Systematic review (12)Phase 3 study (9)Clinical trial (378)Review article (138)Early study (phase 1 or 2) (18)Case report (134)Laboratory or animal research (17)Commentary or editorial (44)Retracted publication (2) Studies currently recruiting participants only (32)

Filter

Publications and studies (1521)

• Renal function in β-thalassemia major patients treated with two different iron-chelation regimes. (2021/12/20) ♡
• Health Status of Patients With β-Thalassemia in the West Bank: A Retrospective-Cohort Study. (2021/12/20) ♡
• Stable Luminescent Poly(Allylaminehydrochloride)-Templated Copper Nanoclusters for Selectively Turn-Off Sensing of Deferasirox in β-Thalassemia Plasma. (2021/12/16) ♡
• The Epidemiology of Neurological Complications in Adults With Sickle Cell Disease: A Retrospective Cohort Study. (2021/12/15) ♡
• Treatment of Erythroid Precursor Cells from β-Thalassemia Patients with Cinchona Alkaloids: Induction of Fetal Hemoglobin Production. (2021/12/14) ♡
• [Regulation effect of siRNA on β-globin in erythrocytes of hemoglobin H disease]. (2021/12/14) ♡
• Newborn Screening Practices for Beta-Thalassemia in the United States. (2021/12/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Optimal strategies for carrier screening and prenatal diagnosis of α- and β-thalassemia. (2021/12/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. β-Thalassemia: evolving treatment options beyond transfusion and iron chelation. (2021/12/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Advances in the management of α-thalassemia major: reasons to be optimistic. (2021/12/10) ♡
• β-Thalassemia minor & renal tubular dysfunction: is there any association? (2021/12/07) ♡
• Bleeding Versus Thrombotic Tendency in Young Children With Beta-Thalassemia Major. (2021/12/06) ♡
• Prognostic factors associated with COVID-19 related severity in sickle cell disease. (2021/12/01) ♡
• Improved Characterization of Complex β-Globin Gene Cluster Structural Variants Using Long-Read Sequencing. (2021/12/01) ♡
• Safety, clinical and laboratory characteristics of donors with thalassemia minor in living donor kidney transplant: a case series. (2021/12/01) ♡
• [The Genotypes and Clinical Characteristics of Thalassemia on Children in Wuhan Region]. (2021/12/01) ♡
• [Prevalence Rate and Risk Factors of Hypothyroidism in Children with Beta Thalassemia Major in Zhuhai Area]. (2021/12/01) ♡
• [Gene Mutation Types and Ethnic Distribution Characteristic of Thalassemia in Guiyang]. (2021/12/01) ♡
• [Analysis of Thalassemia Gene Carriers in 19 482 Pregnant Women from 2015 to 2019 in Guilin, Guangxi]. (2021/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Hepatoprotective effects of metformin in hepatitis C virus-infected adolescents with beta thalassaemia major. (2021/12/01) ♡
• Cognitive Function in Adults with Beta-Thalassemia Major in Oman: A Pilot Study. (2021/11/30) ♡
• Evaluation of the Association of Transferrin Receptor Type 2 Gene Mutation (Y250X) with Iron Overload in Major β- Thalassemia. (2021/11/30) ♡
• The Link of Pancreatic Iron with Glucose Metabolism and Cardiac Iron in Thalassemia Intermedia: A Large, Multicenter Observational Study. (2021/11/26) ♡
• Lysine-specific histone demethylase 1 inhibition enhances robust fetal hemoglobin induction in human β(0)-thalassemia/hemoglobin E erythroid cells. (2021/11/26) ♡
• A Novel Algorithm Using Cell Population Data (VCS Parameters) as a Screening Discriminant between Alpha and Beta Thalassemia Traits. (2021/11/22) ♡
• Hemoglobin A(2) and Heterogeneous Diagnostic Relevance Observed in Eight New Variants of the Delta Globin Gene. (2021/11/19) ♡
• Retracted publicationiThis research has been withdrawn by science itself, for example due to a flaw in the method or unreliable data. Do not use it as support and do not discuss it as evidence. Optimizing sgRNA to Improve CRISPR/Cas9 Knockout Efficiency: Special Focus on Human and Animal Cell. (2021/11/19) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Safety and efficacy of thalidomide in patients with transfusion-dependent β-thalassemia: a randomized clinical trial. (2021/11/18) ♡
• The Alberta Newborn Screening Approach for Sickle Cell Disease: The Advantages of Molecular Testing. (2021/11/16) ♡
• Comparing measurement properties of EQ-5D-Y-3L and EQ-5D-Y-5L in paediatric patients. (2021/11/15) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Safety: A Primary Concern in Thalidomide Use in Thalassemia. (2021/11/15) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Safety: A Primary Concern in Thalidomide Use in Thalassemia: Reply. (2021/11/15) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Fracture prevalence in thalassemia: a systematic review and meta-analysis. (2021/11/13) ♡
• The Post-Storage Performance of RBCs from Beta-Thalassemia Trait Donors Is Related to Their Storability Profile. (2021/11/13) ♡
• Rapid molecular diagnostics of large deletional β(0)-thalassemia (3.5 kb and 45 kb) using colorimetric LAMP in various thalassemia genotypes. (2021/11/12) ♡
• Application of Bayesian Decision Tree in Hematology Research: Differential Diagnosis of β-Thalassemia Trait from Iron Deficiency Anemia. (2021/11/09) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Murine models of sickle cell disease and beta-thalassemia demonstrate pulmonary hypertension with distinctive features. (2021/11/07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparison of Two Alternative Procedures to Obtain Packed Red Blood Cells for β-Thalassemia Major Transfusion Therapy. (2021/11/04) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Novel εγδβ-Thalassemia Deletion Associated with Severe Anemia at Birth and a β-Thalassemia Intermedia Phenotype Later in Life in Three Generations of a Greek Family. (2021/11/01) ♡
• Evaluation of Vascular Health of E-Beta Thalassemia Patients: Effect of Iron Overload. (2021/11/01) ♡
• High prevalence of central hypothyroidism among patients with transfusion dependent thalassemia in Hospital Pulau Pinang: A cross sectional study. (2021/11/01) ♡
• An Evaluation for the Causes of Reduced Hb A(2) and the Molecular Characterization of HBD Variants in Hong Kong. (2021/11/01) ♡
• Profiling of 35 Cases of Hb S/Hb E (HBB: c.20A>T/HBB: c.79G>a), Disease and Association with α-Thalassemia and β-Globin Gene Cluster Haplotypes from Odisha, India. (2021/11/01) ♡
• A Qualitative Study Exploring the Experiences of Mothers Caring for Their Children with Thalassemia in Iran. (2021/11/01) ♡
• Genetic heterogeneity of beta thalassemia mutations in Kahramanmaraş province in Southern Turkey: preliminary report. (2021/10/31) ♡
• Multiplex CRISPR/Cas9 genome editing in hematopoietic stem cells for fetal hemoglobin reinduction generates chromosomal translocations. (2021/10/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Age and genotype dependent erythropoietin protection in COVID-19. (2021/10/26) ♡
• Myocardial longitudinal strain as the first herald of cardiac impairment in very early iron overload state: an echocardiography and biosusceptometry study on beta-thalassemia patients. (2021/10/25) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Molecular Spectrum of α- and β-Thalassemia among Young Individuals of Marriageable Age in Guangdong Province, China. (2021/10/20) ♡
• Genetic and non-genetic factors affecting hemoglobin A(2) expression in a large cohort of Thai individuals: implication for population screening for thalassemia. (2021/10/15) ♡

↑ Back to top

codex.care does not provide medical advice. Always discuss symptoms, medication, and treatment choices with your own healthcare provider.