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Thalassemia (severe form)
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Publications and studies (1521)
- Clinical significance of mutational variants in beta and alpha genes in patients with hemoglobinopathies from two large Greek centers: a complex interplay between genotype and phenotype. (2023/09/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Challenge in diagnosis of hemoglobin E/beta thalassemia during pregnancy: A case report. (2023/09/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current Status of β-Thalassemic Burden in India. (2023/09/01) ♡
- Epidemiological and clinical characteristics of 66 Tunisian Sickle cell syndrome patients. (2023/09/01) ♡
- HLA haplotype frequencies and diversity in patients with hemoglobinopathies. (2023/08/04) ♡
- Association of GDF15 levels with body mass index and endocrine status in β-thalassaemia. (2023/08/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Thalassemia and hemoglobinopathy prevalence in a community-based sample in Sylhet, Bangladesh. (2023/07/19) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Fetal factors disrupt placental and maternal iron homeostasis in murine β-thalassemia. (2023/07/13) ♡
- Prevalence Rate of Thalassemia Carriers among Individuals with Microcytosis or Hypochromia in Portugal. (2023/07/03) ♡
- The Effects of Vitamin D on Myocardial Function Demonstrated by Speckle-Tracking Echocardiography in Children with Beta Thalassemia. (2023/07/01) ♡
- Red cell alloimmunization and associated risk factors in multiply transfused thalassemia patients: A prospective cohort study conducted at a tertiary care center in Northern India. (2023/07/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Beta-thalassemia and vitamin B12 deficiency and associated complement-mediated hemolysis]. (2023/06/18) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nutritional studies in patients with β-thalassemia major: A short review. (2023/06/14) ♡
- Assessment of lung function by spirometry in transfusion-dependent thalassemia patients in a tertiary care center in Sultanate of Oman. (2023/06/01) ♡
- The long-term efficacy in blood transfusions, hematologic parameter changes, and complications after splenectomy in patients with transfusion-dependent thalassemia. (2023/06/01) ♡
- Real-world complication burden and disease management paradigms in transfusion-related β-thalassaemia in Greece: Results from ULYSSES, an epidemiological, multicentre, retrospective cross-sectional study. (2023/05/23) ♡
- The effect of erythroferrone suppression by transfusion on the erythropoietin-erythroferrone-hepcidin axis in transfusion-dependent thalassaemia: A pre-post cohort study. (2023/05/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Erythropoiesis in lower-risk myelodysplastic syndromes and beta-thalassemia. (2023/05/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Amlodipine rescues advanced iron overload cardiomyopathy in hemojuvelin knockout murine model: Clinical implications. (2023/04/21) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Prime editing: A potential treatment option for β-thalassemia. (2023/04/01) ♡
- Genetic Variations of ferroportin-1(FPN1-8CG), TMPRSS6 (rs855791) and Hemojuvelin (I222N and G320V) Among a Cohort of Egyptian β-Thalassemia Major Patients. (2023/04/01) ♡
- An Epidemiological Study of the Quality of Life of Children With Beta-Thalassemia Major (β-TM) and Its Correlates in Kolkata, West Bengal, India. (2023/03/29) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Opening Pandora's box: abnormal genetic carrier screening and need for lifetime follow-up. (2023/03/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Development of a Thalassemia International Prognostic Scoring System (TIPSS). (2023/03/01) ♡
- Serum Ferritin Levels and Other Associated Parameters with Diabetes Mellitus in Adult Patients Suffering from Beta Thalassemia Major. (2023/02/07) ♡
- Genetic variant of endothelial protein C receptor genes and its serum level in B thalassemic children. (2023/02/01) ♡
- Pre-transplantation vitamin D deficiency increases acute graft-versus-host disease after hematopoietic stem cell transplantation in thalassemia major patients. (2023/02/01) ♡
- Differential proteomic patterns of plasma extracellular vesicles show potential to discriminate β-thalassemia subtypes. (2023/01/25) ♡
- Predictors of health state utility values using SF-6D for Chinese adult patients with β-thalassemia major. (2023/01/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rise of the planet of rare anemias: An update on emerging treatment strategies. (2023/01/09) ♡
- An efficient isoelectric focusing of microcolumn array chip for screening of adult Beta-Thalassemia. (2023/01/01) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. CRISPR/Cas9, a promising approach for the treatment of β-thalassemia: a systematic review. (2023/01/01) ♡
- The effect of ferritin levels on distal femoral cartilage thickness in patients with beta thalassaemia major. (2023/01/01) ♡
- Pro-haemostatic effect of DDAVP is partially derived through non-classical (CD14(dim) /CD16(++) ) monocytes residing the spleen. (2023/01/01) ♡
- Human genetic diversity alters off-target outcomes of therapeutic gene editing. (2023/01/01) ♡
- Safety and Efficacy of Thalidomide and Hydroxyurea Combination in Beta Thalassemia Patients. (2023/01/01) ♡
- A First Clinical and Molecular Study of Rare IVS-II-806 (G > C) (HBB:c.316-45G > C) Variant in the β-globin Gene: A Possibly Benign Variant. (2023/01/01) ♡
- Gene editing for sickle cell disease and transfusion dependent thalassemias- A cure within reach. (2023/01/01) ♡
- Oxidative Stress in Beta-thalassemia Patients: Role of Enzymatic and Non-enzymatic Modulators. (2023/01/01) ♡
- Does TNF-α 308 G/A (rs1800629) gene polymorphism associate with liver and pancreas disorders in Iraqi adults with beta thalassemia major? (2023/01/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Determine the Efficacy and Safety of Luspatercept in Adults With Non Transfusion Dependent Beta (β)-Thalassemia (2023-12-20) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, Pharmacokinetics (PK), Pharmacodynamics (PD) and Preliminary Efficacy of VIT-2763 in β-thalassaemia (2023-12-14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess the Safety, Tolerability, and Efficacy of ST-400 for Treatment of Transfusion-Dependent Beta-thalassemia (TDT) (2023-12-14) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Thalidomide and Hydroxyurea Combination in β-Thalassemia Patients (2023-12-01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Deciphering Effects of Thalidomide on Red Blood Cells in Transfusion Dependents Beta Thalassemia Patients (2023-11-24) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. "Iron Overload and Endocrinological Diseases" (2023-11-18) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Longitudinal Study on the QoL of Pediatric Patients After HSCT and Its Influencing Factors (2023-10-23) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Efficacy Evaluation of Autologous CRISPR-Cas12b Edited Hematopoietic Stem Cells (2023-10-17) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Bone Density Change in Children With Beta Thalassemia Major (2023-10-05) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Thalassemic Iron Overload Cardiomyopathy is Ameliorated by Taurine Supplementation (2023-10-03) ♡
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