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Progressive supranuclear palsy (PSP)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (31)Meta-analysis (11)Systematic review (13)Phase 3 study (4)Randomized Controlled Trial (3)Clinical trial (188)Review article (153)Early study (phase 1 or 2) (11)Single patient description (77)Laboratory or animal study (6)Commentary or Editorial (50) Studies currently recruiting participants only (32)

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Publications and studies (1194)

• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Deep transcranial magnetic stimulation in progressive supranuclear palsy: a randomized double-blind, cross-over study. (2025/12/01) ♡
• Dynamic multi-scale deep learning with mixture of experts for differentiating iNPH and PSP using MRI. (2025/12/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Cerebrospinal fluid biomarkers for diagnosis of Parkinson's disease: a systematic review and network meta-analysis. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Clinical Framework for Motor Rehabilitation in Parkinsonism: Integrating Individualized and Syndrome-Specific Approaches. (2025/11/27) ♡
• Inflammation PET and plasma neurofilament light predict survival in people with progressive supranuclear palsy. (2025/11/27) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Unlocking the Sugar Code: Implications and Consequences of Glycosylation in Alzheimer's Disease and Other Tauopathies. (2025/11/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Single-cell Spatial Transcriptional Profiling Uncovers Heterogeneous Cellular Responses to Pathogenic Tau in a Mouse Model of Neurodegeneration. (2025/11/19) ♡
• Progressive supranuclear palsy against everyone else: a look into the specificity of MRI markers. (2025/11/15) ♡
• Levodopa exposure and nigral neuroinflammation in parkinsonian disorders: A postmortem study of 63 cases. (2025/11/11) ♡
• Refining the diagnostic accuracy of Parkinsonian disorders using metaphenomic annotation of the clinicopathological literature. (2025/11/10) ♡
• Acoustic Vowel Metrics as Correlates of Dysphagia and Dysarthria in Brainstem Neurodegenerative Diseases. (2025/11/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. NDPACX: a newly defined X-linked Parkinsonian syndrome associated with SLC9A6 hemizygote mutation. (2025/11/05) ♡
• Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo. (2025/11/04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. No anti-IgLON5 antibody in carefully diagnosed PSP patients with "atypical" or variant clinical features. (2025/11/01) ♡
• Deceleration Capacity as a Marker of Autonomic Cardiac Modulation in Prodromal and Manifest Parkinson's Disease, Multiple System Atrophy, and Progressive Supranuclear Palsy. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Leveraging Proteomics to Explore the Molecular Mechanisms of Primary Tauopathies. (2025/11/01) ♡
• The discriminative linguistic profiles of progressive supranuclear palsy and Parkinson's disease. (2025/11/01) ♡
• Automated MRI-Based Classification of Parkinsonism: A Deep Learning Approach to Distinguish PD From PSP. (2025/11/01) ♡
• Association between visual hallucinations and α-synuclein oligomers in patients with dementia with Lewy bodies. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond Parkinson's Disease: A Narrative Review of Neuromelanin MRI in Neurodegenerative Diseases. (2025/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. CORTICOBASAL SYNDROME PRESENTING AS A PROGRESSIVE HEMIPARETIC SYNDROME: A CASE REPORT. (2025/11/01) ♡
• The underlying causes of eye movement disorders and ataxia. (2025/10/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. TDP-43-proteinopathy at the crossroads of tauopathy: on copathology and current and prospective biomarkers. (2025/10/28) ♡
• Reviewer Comment on Kazemi et al. "Assessment of Clinical and Demographic Factors Influencing the Severity of Levodopa-Induced Dyskinesia". (2025/10/24) ♡
• LRRK2 kinase-mediated accumulation of lysosome-associated phospho-Rabs in tauopathies and synucleinopathies. (2025/10/23) ♡
• Potential Role of Transferrin and Vascular Cell Adhesion Molecule 1 in Differential Diagnosis Among Patients with Tauopathic Atypical Parkinsonian Syndromes. (2025/10/23) ♡
• Consensus meta-analysis of genome-wide association studies for Alzheimer's disease and related dementia. (2025/10/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Toward Biology-Driven Diagnosis of Atypical Parkinsonian Disorders. (2025/10/21) ♡
• Peripheral immunity patterns, imaging features, and clinical outcomes in patients with gait impairment and ventriculomegaly on brain MRI. (2025/10/20) ♡
• Early subtypes and progressions of progressive supranuclear palsy: a data-driven brain bank study. (2025/10/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Neuro-Ophthalmologic Manifestations of SPG7-Associated Disease. (2025/10/16) ♡
• Protein fingerprints of brain-derived extracellular vesicles predict types of tau pathology. (2025/10/14) ♡
• Anti-tau VHH therapy against PHF6: a safe approach to slowing the phenotype of tau pathology. (2025/10/07) ♡
• Cross-sectional and longitudinal validation of short and long versions of the progressive supranuclear palsy quality of life scale. (2025/10/06) ♡
• Remote Cortical Network for Frontal Cognitive Symptoms Derived from Tau Accumulation in Progressive Supranuclear Palsy. (2025/10/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Patient with Progressive Supranuclear Palsy Initially Diagnosed as Anxiety and Depression. (2025/10/01) ♡
• A Bayesian analysis of diagnostic timelines across Alzheimer's disease, frontotemporal dementia, and other neurodegenerative conditions. (2025/09/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Understanding Tau pathology: Insights from animal models. (2025/09/18) ♡
• Patterns and causes of supranuclear vertical gaze palsy: A retrospective, single-institutional study in 113 patients. (2025/09/18) ♡
• [Classification and Clinical Characteristics of Dementia]. (2025/09/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Multi-ancestry genome-wide meta-analysis of 56,241 individuals identifies known and novel cross-population and ancestry-specific associations as novel risk loci for Alzheimer's disease. (2025/07/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Prediagnostic Phase of Progressive Supranuclear Palsy in a Longitudinal Epidemiological Study of Dementia and Aging. (2025/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Utilizing quantitative susceptibility mapping to differentiate primary lateral sclerosis from progressive supranuclear palsy: A case report. (2025/06/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Ameliorating freezing of gait with levodopa treatment: a lesson from an illustrative case of progressive supranuclear palsy. (2025/06/01) ♡
• ADNP is essential for sex-dependent hippocampal neurogenesis, through male unfolded protein response and female mitochondrial gene regulation. (2025/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Carnitine supplementation in progressive supranuclear palsy. (2025/06/01) ♡
• Peripheral innate immunophenotype in neurodegenerative disease: blood-based profiles and links to survival. (2025/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rehabilitation of Women with Neurodegenerative Diseases. (2025/05/01) ♡
• Head position control strategies in progressive Supranuclear Palsy versus Idiopathic Parkinson's Disease during dynamic-on-static platform tilt. (2025/04/16) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pathological study of progressive supranuclear palsy the cases with mutations in Bassoon. (2025/04/01) ♡

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