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Progressive supranuclear palsy (PSP)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (31)Meta-analysis (11)Systematic review (13)Phase 3 study (4)Randomized Controlled Trial (3)Clinical trial (188)Review article (154)Early study (phase 1 or 2) (11)Single patient description (77)Laboratory or animal study (6)Commentary or Editorial (50) Studies currently recruiting participants only (32)

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Publications and studies (1195)

• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. A Study to Evaluate the Efficacy of NIO752 in Participants With Progressive Supranuclear Palsy (2026-07-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cholinergic Mechanisms of Attentional-motor Integration and Gait Dysfunction in Parkinson Disease (UDALL) (2026-07-27) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. First-in-Human Study for the Safety and Evaluation of Two 4R Tau Ligands as Potential PET Radioligands for Imaging Tau Protein in the Brain (2026-07-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Gait Analysis in Neurological Disease (2026-07-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Digital Health Technologies for Progressive Supranuclear Palsy and Dementia With Lewy Bodies (2026-07-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Individualized Transcranial Magnetic Stimulation in Parkinsonian Disorders (2026-06-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Neurologic Stem Cell Treatment Study (2026-06-26) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Trial of Parkinson's And Zoledronic Acid (2026-06-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Research of Biomarkers in Parkinson Disease (2026-06-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Biomarkers in Parkinsonian Syndromes (2026-06-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Early Molecular Biomarkers for Differentiating Parkinsonian Syndromes (2026-05-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Molecular Anatomic Imaging Analysis of Tau in Progressive Supranuclear Palsy (2026-05-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tracking and Predicting How Brain Damage Spreads in Neurodegenerative Diseases (2026-05-05) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. AMX0035 and Progressive Supranuclear Palsy (2026-04-30) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen B: LM11A-31 (2026-04-27) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. The Progressive Supranuclear Palsy Clinical Trial Platform - Regimen A: AADvac1 (2026-04-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Evaluate the Feasibility of Syde® Digital Endpoints for Monitoring Patients With Progressive Supranuclear Palsy - Richardson Syndrome (PSP-R) (2026-04-22) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 2a Study of TPN-101 in Patients With Progressive Supranuclear Palsy (PSP) (2026-04-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Swedish BioFINDER 2 Study (2026-04-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Ultra-High Resolution PET in Aging, Neurodegeneration and Psychotic Disorders (2026-04-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Community Outreach for Palliative Engagement -- Parkinson Disease (2026-03-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. GV1001 Subcutaneous(SC) for the Treatment of Progressive Supranuclear Palsy (PSP) (2026-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Synaptic Loss in Multiple System Atrophy (2026-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers (2026-02-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging (2026-01-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. UPenn Observational Research Repository on Neurodegenerative Disease (2026-01-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes (2026-01-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The CurePSP Genetics Program (2026-01-14) ♡
• 4R-tau seeding activity reveals molecular subtypes in progressive supranuclear palsy. (2025/12/31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Plasma NFL, GFAP, sTREM2, pTau231, and clinical severity in progressive supranuclear palsy. (2025/12/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Paraneoplastic progressive supranuclear palsy: a case report and literature review. (2025/12/26) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. The Role of MRI in Capturing Phenotypic Variability in Progressive Supranuclear Palsy: Lessons for Future Clinical Trials. (2025/12/23) ♡
• Patterns of Longitudinal Regional Brain Atrophy in Patients With Different Progressive Supranuclear Palsy Clinical Variants. (2025/12/23) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Progressive Supranuclear Palsy With Post-traumatic Frontal Lobe Damage Mimicking Anti-IgLON5 Antibody Disease. (2025/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Diagnostic utility of biomarkers in progressive supranuclear palsy: toward a biotyping framework. (2025/12/17) ♡
• Inflammatory and Neurotrophic Factors and Their Connection to Quality of Life in Progressive Supranuclear Palsy-Single-Center Study. (2025/12/17) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Methodological considerations for MRI biomarkers in progressive supranuclear palsy. (2025/12/15) ♡
• Progressive supranuclear palsy and corticobasal syndrome: cross-sectional study of palliative care needs. (2025/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Quantification of Neuromelanin as a Neuroimaging Biomarker for Parkinson's Disease. (2025/12/10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multiple System Atrophy Without Dysautonomia: An Autopsy-Confirmed Study. (2025/12/09) ♡
• Correction to: Evaluation of disproportionately enlarged subarachnoid-space hydrocephalus in progressive supranuclear palsy. (2025/12/09) ♡
• The Paper-Toss Test: enhancing bedside recognition of corticobasal syndrome. (2025/12/08) ♡
• Brain atrophy and cholinergic denervation in progressive supranuclear palsy: an MRI and [(18)F]-FEOBV PET study. (2025/12/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Richardson Syndrome Variant of Progressive Supranuclear Palsy: A Case Report. (2025/12/02) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. AZP2006 in Progressive Supranuclear Palsy: Outcomes from a Phase 2a Multicenter, Randomized Trial, and Open-Label Extension on Safety, Biomarkers, and Disease Progression. (2025/12/01) ♡
• A novel lncRNA FAM151B-DT regulates degradation of aggregation prone proteins. (2025/12/01) ♡
• Brain linear measurement index in the differential diagnosis between idiopathic normal pressure hydrocephalus and progressive supranuclear palsy. (2025/12/01) ♡
• Investigating the impact of white matter hyperintensities on longitudinal progression in progressive supranuclear palsy. (2025/12/01) ♡
• Sleep phenotypes of α-synucleinopathies and tauopathies with Parkinsonism. (2025/12/01) ♡
• Data-Driven differentiation of idiopathic Normal-Pressure hydrocephalus and progressive supranuclear palsy via automated volumetric analysis. (2025/12/01) ♡

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