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Primary lateral sclerosis
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Publications and studies (2508)
- 6-OH-BDE-47 exposure-induced Parkinson's disease pathology in Sprague Dawley rat. (2020/04/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. A Prospective, Crossover Survey Study of Child- and Proxy-Reported Quality of Life According to Spinal Muscular Atrophy Type and Medical Interventions. (2020/04/01) ♡
- Evaluation of body composition as a potential biomarker in spinal muscular atrophy. (2020/04/01) ♡
- Impact of scoliosis surgery on pulmonary function in patients with muscular dystrophies and spinal muscular atrophy. (2020/04/01) ♡
- Thirty years of translational research in Mobility Medicine: Collection of abstracts of the 2020 Padua Muscle Days. (2020/04/01) ♡
- Exploratory identification of predictive biomarkers in randomized trials with normal endpoints. (2020/03/30) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role of Alcohol Drinking in Alzheimer's Disease, Parkinson's Disease, and Amyotrophic Lateral Sclerosis. (2020/03/27) ♡
- In Silico Identification of a Key Residue for Substrate Recognition of the Riboflavin Membrane Transporter RFVT3. (2020/03/23) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Riluzole-induced interstitial lung disease is a rare and potentially life-threatening adverse event successfully treated with high-dose steroid therapy: Case reports and review of the literature. (2020/03/15) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Technical success rate and safety of radiologically inserted gastrostomy versus percutaneous endoscopic gastrostomy in motor neuron disease patients undergoing: A systematic review and meta-analysis. (2020/03/15) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Electroacupuncture Therapy Ameliorates Motor Dysfunction via Brain-Derived Neurotrophic Factor and Glial Cell Line-Derived Neurotrophic Factor in a Mouse Model of Parkinson's Disease. (2020/03/09) ♡
- Serum creatinine is a biomarker of progressive denervation in spinal muscular atrophy. (2020/03/03) ♡
- The Clinical Journey of Patients with Riboflavin Transporter Deficiency Type 2. (2020/03/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Neuropsychiatric history influences cognition and behaviour in MND. (2020/03/01) ♡
- Regional spreading of symptoms at diagnosis as a prognostic marker in amyotrophic lateral sclerosis: a population-based study. (2020/03/01) ♡
- Relationship between neuropsychiatric disorders and cognitive and behavioural change in MND. (2020/03/01) ♡
- Zonisamide enhances neurite outgrowth from adult rat dorsal root ganglion neurons, but not proliferation or migration of Schwann cells. (2020/03/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Current and future treatments of spinal muscular atrophy. (2020/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A new case of SMABF2 diagnosed in stillbirth expands the prenatal presentation and mutational spectrum of ASCC1. (2020/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Chiari Malformation and Syringomyelia Associated with Hirayama Disease. (2020/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Intrathecal nusinersen treatment after ventriculo-peritoneal shunt placement: A case report focusing on the neurofilament light chain in cerebrospinal fluid. (2020/03/01) ♡
- Neuroendocrine Disturbances in Neurodegenerative Disorders: A Scoping Review. (2020/03/01) ♡
- Identification of novel SMN1 subtle mutations using an allelic-specific RT-PCR. (2020/03/01) ♡
- Serum 25-hydroxyvitamin D in amyotrophic lateral sclerosis: mendelian randomization study. (2020/03/01) ♡
- Life Course Adiposity and Amyotrophic Lateral Sclerosis: A Mendelian Randomization Study. (2020/03/01) ♡
- Trajectory of change in the swallowing status in spinal muscular atrophy type I. (2020/03/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Taste disorder in facial onset sensory and motor neuronopathy: a case report. (2020/02/29) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prediagnostic plasma polyunsaturated fatty acids and the risk of amyotrophic lateral sclerosis. (2020/02/25) ♡
- Gastrostomy uptake in motor neurone disease: a mixed-methods study of patients' decision making. (2020/02/25) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Emerging small-molecule therapeutic approaches for amyotrophic lateral sclerosis and frontotemporal dementia. (2020/02/15) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. [Acupuncture at pharyngeal acupoints for true bulbar paralysis after cerebral infarction: a randomized controlled trial]. (2020/02/12) ♡
- Oxidative misfolding of Cu/Zn-superoxide dismutase triggered by non-canonical intramolecular disulfide formation. (2020/02/01) ♡
- Mechanism of visual network dysfunction in relapsing-remitting multiple sclerosis and its relation to cognition. (2020/02/01) ♡
- Behavioral manifestations in a Brazilian non-demented C9orf72-negative ALS population. (2020/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Inhibition of vertebrate aldehyde oxidase as a therapeutic treatment for cancer, obesity, aging and amyotrophic lateral sclerosis. (2020/02/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Posteroanterior cervical transcutaneous spinal stimulation targets ventral and dorsal nerve roots. (2020/02/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Drosophila SMN2 minigene reporter model identifies moxifloxacin as a candidate therapy for SMA. (2020/02/01) ♡
- Reliability and validity of speech & pause measures during passage reading in ALS. (2020/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exercise, diet and stress as modulators of gut microbiota: Implications for neurodegenerative diseases. (2020/02/01) ♡
- Loss of appetite in amyotrophic lateral sclerosis is associated with weight loss and decreased calorie consumption independent of dysphagia. (2020/02/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effect of High-Caloric Nutrition on Survival in Amyotrophic Lateral Sclerosis. (2020/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rasagiline and selegiline modulate mitochondrial homeostasis, intervene apoptosis system and mitigate α-synuclein cytotoxicity in disease-modifying therapy for Parkinson's disease. (2020/02/01) ♡
- Clinical and Lifestyle Factors and Risk of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study. (2020/01/30) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Bidens pilosa Extract Administered after Symptom Onset Attenuates Glial Activation, Improves Motor Performance, and Prolongs Survival in a Mouse Model of Amyotrophic Lateral Sclerosis. (2020/01/29) ♡
- Mechanism of the neuroprotective effect of injecting brain cells on ST36 in an animal model of Parkinson's disease. (2020/01/19) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role of Propriospinal Neurons in Control of Respiratory Muscles and Recovery of Breathing Following Injury. (2020/01/17) ♡
- Association between macronutrient intake and amyotrophic lateral sclerosis prognosis. (2020/01/01) ♡
- Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Vitamin D supplementation has no effects on progression of motor dysfunction in amyotrophic lateral sclerosis (ALS). (2020/01/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alternative Splicing of ALS Genes: Misregulation and Potential Therapies. (2020/01/01) ♡
- A Standard Framework for Population-Based Neuroepidemiological Studies in Tropical Low- and Middle-Income Countries. (2020/01/01) ♡
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