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Primary lateral sclerosis

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (123)Meta-analysis (29)Treatment guideline (6)Systematic review (51)Randomized controlled trial (19)Phase 3 study (18)Clinical trial (658)Review article (336)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (123)Case description (120)Commentary or editorial (46)Retracted publication (1) Studies currently recruiting participants only (31)

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Publications and studies (2508)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Respiratory management of children with spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathogenesis and therapeutic targets in spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Functional and surgical treatments in patients with spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. State of the art for motor function assessment tools in spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multidisciplinary approach and psychosocial management of spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ethical aspects in the care of a child with infantile spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular diagnosis and genetic counseling for spinal muscular atrophy (SMA). (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The microglial component of amyotrophic lateral sclerosis. (2020/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. [Incorporating spinal muscular atrophy analysis by next-generation sequencing into a comprehensive multigene panel for neuromuscular disorders]. (2020/12/01) ♡
• Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis. (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. 25 years of the SMN genes: the Copernican revolution of spinal muscular atrophy. (2020/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Transient hyperreflexia: An early diagnostic clue in later-onset spinal muscular atrophy. (2020/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Outcome of Adult Spinal Muscular Atrophy Patients Treated with Nusinersen: A Case Series Review. (2020/12/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS. (2020/11/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New technologies and Amyotrophic Lateral Sclerosis - Which step forward rushed by the COVID-19 pandemic? (2020/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation. (2020/11/09) ♡
• Relationship between Dietary Fiber Intake and the Prognosis of Amytrophic Lateral Sclerosis in Korea. (2020/11/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic Targeting. (2020/11/04) ♡
• Social Cognition Deficits Are Pervasive across Both Classical and Overlap Frontotemporal Dementia Syndromes. (2020/11/04) ♡
• Echinacoside protects dopaminergic neurons by inhibiting NLRP3/Caspase-1/IL-1β signaling pathway in MPTP-induced Parkinson's disease model. (2020/11/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Serum creatinine levels in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis. (2020/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hematologic presentation and the role of untargeted metabolomics analysis in monitoring treatment for riboflavin transporter deficiency. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuropathology of primary lateral sclerosis. (2020/11/01) ♡
• Neurophysiological features of primary lateral sclerosis. (2020/11/01) ♡
• Genetics of primary lateral sclerosis. (2020/11/01) ♡
• The clinical spectrum of primary lateral sclerosis. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Better understanding the neurobiology of primary lateral sclerosis. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuroimaging in primary lateral sclerosis. (2020/11/01) ♡
• Measuring disease progression in primary lateral sclerosis. (2020/11/01) ♡
• Clinical care and therapeutic trials in PLS. (2020/11/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Preface: promoting research in PLS: current knowledge and future challenges. (2020/11/01) ♡
• "Motor Band Sign" in Susceptibility-Weighted Imaging in Motor Neuron Disease. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease. (2020/10/30) ♡
• The efficacy and safety of Chinese herbal compound combined with western medicine for amyotrophic lateral sclerosis: A protocol for systematic review and meta-analysis. (2020/10/23) ♡
• Phosphoglycerate Mutase 1 Prevents Neuronal Death from Ischemic Damage by Reducing Neuroinflammation in the Rabbit Spinal Cord. (2020/10/08) ♡
• Augmented Buyang Huanwu Decoction facilitates axonal regeneration after peripheral nerve transection through the regulation of inflammatory cytokine production. (2020/10/05) ♡
• Voice Conversion for Persons with Amyotrophic Lateral Sclerosis. (2020/10/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Predictive factors for gastrostomy at time of diagnosis and impact on survival in patients with amyotrophic lateral sclerosis. (2020/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Interleukin-1 receptor antagonist, interleukin-2 receptor alpha subunit and amyotrophic lateral sclerosis. (2020/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Course in a Patient With Spinal Muscular Atrophy Type 0 Treated With Nusinersen and Onasemnogene Abeparvovec. (2020/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic lateral sclerosis: a clinical review. (2020/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic lateral sclerosis: update on clinical management. (2020/10/01) ♡
• Predictive factors for prognosis after gastrostomy placement in routine non-invasive ventilation users ALS patients. (2020/09/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Metabolism Regulation and Redox State: Insight into the Role of Superoxide Dismutase 1. (2020/09/10) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Reply to Comment on "Environmental and Occupational Risk Factors of Amyotrophic Lateral Sclerosis: A Population-Based Case-Control Study". (2020/09/07) ♡
• Increased resting energy expenditure compared with predictive theoretical equations in amyotrophic lateral sclerosis. (2020/09/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ASAH1 pathogenic variants associated with acid ceramidase deficiency: Farber disease and spinal muscular atrophy with progressive myoclonic epilepsy. (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Understanding and managing metabolic dysfunction in Amyotrophic Lateral Sclerosis. (2020/09/01) ♡
• Effectiveness of percutaneous endoscopic gastrostomy in amyotrophic lateral sclerosis. (2020/09/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Effect of high-caloric nutrition on serum neurofilament light chain levels in amyotrophic lateral sclerosis. (2020/09/01) ♡

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