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ALS (amyotrophic lateral sclerosis)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the heaviest evidence (99)Meta-analysis (26)Treatment guideline (4)Systematic review (40)Phase 3 Study (15)Randomized trial (14)Clinical trial (625)Review article (535)Early study (phase 1 or 2) (12)Single patient description (77)Laboratory or animal research (69)Commentary or editorial (40)Retracted publication (1) Studies currently recruiting participants only (31)

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Publications and studies (2470)

• Photo-Oxygenation: An Innovative New Therapeutic Approach Against Amyloidoses. (2021/01/01) ♡
• Pathological manifestation of human endogenous retrovirus K in frontotemporal dementia. (2021/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mixed pathologies mimicking motor neuron disease: a case report and review of the literature. (2021/01/01) ♡
• Inflammatory Cytokine Levels in Patients with Sporadic Amyotrophic Lateral Sclerosis. (2021/01/01) ♡
• Distribution Changes of Neural Precursor Cells in the Brain Stem of Tg(SOD1*G93A)1Gur Mice. (2021/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Safety and Biomarker Study of ALZT-OP1a in Subjects With Mild-Moderate ALS Disease (2021-11-08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role of Edaravone as a Treatment Option for Patients with Amyotrophic Lateral Sclerosis. (2020/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Immunotherapy Induced Myasthenic-Like Syndrome in a Metastatic Melanoma Patient With Amyotrophic Lateral Sclerosis. (2020/12/28) ♡
• Advances in genetics research in the pathogenesis of amyotrophic lateral sclerosis. (2020/12/28) ♡
• Kampō medicine and Muro disease (Amyotrophic Lateral Sclerosis and Parkinsonism-Dementia Complex): Postscript and Historical Footnote. (2020/12/25) ♡
• TDP-43-specific Autoantibody Decline in Patients With Amyotrophic Lateral Sclerosis. (2020/12/24) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Pretreatment Effect of Inflammatory Stimuli and Characteristics of Tryptophan Transport on Brain Capillary Endothelial (TR-BBB) and Motor Neuron Like (NSC-34) Cell Lines. (2020/12/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Paraoxonase Role in Human Neurodegenerative Diseases. (2020/12/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. How to Build and to Protect the Neuromuscular Junction: The Role of the Glial Cell Line-Derived Neurotrophic Factor. (2020/12/24) ♡
• Who and Why? Requests for Presymptomatic Genetic Testing for Amyotrophic Lateral Sclerosis/Frontotemporal Dementia vs Huntington Disease. (2020/12/24) ♡
• LSM12-EPAC1 defines a neuroprotective pathway that sustains the nucleocytoplasmic RAN gradient. (2020/12/23) ♡
• Cognitive Performance of Patients with Adult 5q-Spinal Muscular Atrophy and with Amyotrophic Lateral Sclerosis. (2020/12/23) ♡
• Frontal Functional Network Disruption Associated with Amyotrophic Lateral Sclerosis: An fNIRS-Based Minimum Spanning Tree Analysis. (2020/12/23) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. The Downregulation of c19orf12 Negatively Affects Neuronal and Musculature Development in Zebrafish Embryos. (2020/12/23) ♡
• Trends and outcomes associated with gastrostomy tube placement in common neurodegenerative disorders. (2020/12/23) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Association of a Variant of Unknown Significance in the FIG4 Gene With Frontotemporal Dementia and Slowly Progressing Motoneuron Disease: A Case Report Depicting Common Challenges in Clinical and Genetic Diagnostics of Rare Neuropsychiatric and Neurologic Disorders. (2020/12/22) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Early-Onset Behavioral Variant Frontotemporal Dementia in Patient With Retrotransposed Full-Length Transcript of Matrin-3 Variant 5. (2020/12/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. C9orf72 and the Care of the Patient With ALS or FTD: Progress and Recommendations After 10 Years. (2020/12/21) ♡
• Poor Bone Quality in Patients With Amyotrophic Lateral Sclerosis. (2020/12/18) ♡
• Early Referral to an ALS Center Reduces Several Months the Diagnostic Delay: A Multicenter-Based Study. (2020/12/18) ♡
• Wildtype σ1 receptor and the receptor agonist improve ALS-associated mutation-induced insolubility and toxicity. (2020/12/18) ♡
• AggreCount: an unbiased image analysis tool for identifying and quantifying cellular aggregates in a spatially defined manner. (2020/12/18) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Exosc2 deficiency leads to developmental disorders by causing a nucleotide pool imbalance in zebrafish. (2020/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. C9orf72 Frontotemporal Dementia and/or Amyotrophic Lateral Sclerosis. (2020/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Dysfunctional Autophagy and Endolysosomal System in Neurodegenerative Diseases: Relevance and Therapeutic Options. (2020/12/17) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Palmitoylethanolamide: A Nutritional Approach to Keep Neuroinflammation within Physiological Boundaries-A Systematic Review. (2020/12/15) ♡
• Skeletal Muscle-Restricted Expression of Human SOD1 in Transgenic Mice Causes a Fatal ALS-Like Syndrome. (2020/12/14) ♡
• Humoral Influence of Repeated Lineage-Negative Stem/Progenitor Cell Administration on Articulatory Functions in ALS Patients. (2020/12/14) ♡
• Fasciculation frequency is a questionable biomarker for motor unit loss in amyotrophic lateral sclerosis. (2020/12/11) ♡
• Accurate interpretation of fasciculation frequency in amyotrophic lateral sclerosis hinges on both muscle type and stage of disease. (2020/12/11) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Cytoplasmic Expression of the ALS/FTD-Related Protein TDP-43 Decreases Global Translation Both in vitro and in vivo. (2020/12/08) ♡
• Correlational Analysis of ALS Progression and Serum NfL Measured by Simoa Assay in Chinese Patients. (2020/12/03) ♡
• Genomic Portrait of a Sporadic Amyotrophic Lateral Sclerosis Case in a Large Spinocerebellar Ataxia Type 1 Family. (2020/12/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Table olives and health: a review. (2020/12/02) ♡
• Repeatability of Commonly Used Speech and Language Features for Clinical Applications. (2020/12/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Flavonoids targeting NRF2 in neurodegenerative disorders. (2020/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The microglial component of amyotrophic lateral sclerosis. (2020/12/01) ♡
• Magnetic resonance spectroscopy reveals mitochondrial dysfunction in amyotrophic lateral sclerosis. (2020/12/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Empty mesoporous silica particles significantly delay disease progression and extend survival in a mouse model of ALS. (2020/11/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recent advances in understanding amyotrophic lateral sclerosis and emerging therapies. (2020/11/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New technologies and Amyotrophic Lateral Sclerosis - Which step forward rushed by the COVID-19 pandemic? (2020/11/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Lipid Peroxidation and Antioxidant Supplementation in Neurodegenerative Diseases: A Review of Human Studies. (2020/11/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. PINK1/PARKIN signalling in neurodegeneration and neuroinflammation. (2020/11/09) ♡
• Relationship between Dietary Fiber Intake and the Prognosis of Amytrophic Lateral Sclerosis in Korea. (2020/11/07) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic Lateral Sclerosis and Autophagy: Dysfunction and Therapeutic Targeting. (2020/11/04) ♡

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