← All diseases Brain and nervous system

ALS (amyotrophic lateral sclerosis)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the heaviest evidence (99)Meta-analysis (26)Treatment guideline (4)Systematic review (40)Phase 3 Study (15)Randomized trial (14)Clinical trial (625)Overview article (537)Early study (phase 1 or 2) (12)Single patient description (77)Laboratory or animal research (69)Commentary or editorial (40)Retracted publication (1) Studies currently recruiting participants only (32)

Filter

Publications and studies (2477)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. COVID-19 Amyotrophic Lateral Sclerosis (ALS) Registry (2023-03-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Feasibility of Speech Phenotyping for Remote Assessment of Neurodegenerative and Psychiatric Disorders (2023-03-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. SWITCH II Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis (2023-03-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Circulating Biomarker for Amyotrophic Lateral Sclerosis (ALS) (2023-03-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Counterfactual Thinking in Amyotrophic Lateral Sclerosis (2023-03-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Speech Analysis in ALS Patients (2023-03-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of Oral Levosimendan on Respiratory Function in Patients With Amyotrophic Lateral Sclerosis (ALS): Open-Label Extension (2023-03-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Diaphragm Pacing System (DPS) In Participants With Amyotrophic Lateral Sclerosis (ALS) (2023-03-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of Nuedexta on Bulbar Physiology and Function in ALS (2023-03-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open Label Extension of TUDCA-ALS Study (2023-03-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Colchicine for Amyotrophic Lateral Sclerosis (2023-03-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS (2023-02-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Delineating Swallowing Impairment and Decline in ALS (2023-02-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Determining Feasibility and Acceptability of Sharing Video Recordings With Patients With ALS and Caregivers (2023-02-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Effect of Low-Intensity Combined Exercises in Patients With Early Stage ALS. (2023-02-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ALS Testing Through Home-based Outcome Measures (2023-02-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Genetics of Familial and Sporadic ALS (2023-01-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of ALS Reversals 4: LifeTime Exposures (2023-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. An Efficacy and Safety Study of Ravulizumab in ALS Participants (2023-01-10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Investigations of Protein Aggregation in the Pathogenesis of Amyotrophic Lateral Sclerosis. (2022/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Extracellular Vesicles in Amyotrophic Lateral Sclerosis. (2022/12/31) ♡
• Coordinated cadherin functions sculpt respiratory motor circuit connectivity. (2022/12/30) ♡
• Transcriptomic analysis of human ALS skeletal muscle reveals a disease-specific pattern of dysregulated circRNAs. (2022/12/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Coexisting amyotrophic lateral sclerosis and chorea: A case report and literature review. (2022/12/30) ♡
• Therapeutic Effect of Rapamycin on TDP-43-Related Pathogenesis in Ischemic Stroke. (2022/12/30) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Amyotrophic lateral sclerosis with primary progressive aphasia: a case report and literature review. (2022/12/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Amyotrophic Lateral Sclerosis Pathoetiology and Pathophysiology: Roles of Astrocytes, Gut Microbiome, and Muscle Interactions via the Mitochondrial Melatonergic Pathway, with Disruption by Glyphosate-Based Herbicides. (2022/12/29) ♡
• Gut microbiota links with cognitive impairment in amyotrophic lateral sclerosis: A multi-omics study. (2022/12/28) ♡
• What Is Amyotrophic Lateral Sclerosis? (2022/12/27) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. TDP-43 dysregulation and neuromuscular junction disruption in amyotrophic lateral sclerosis. (2022/12/27) ♡
• Toward structural-omics of the bovine retinal pigment epithelium. (2022/12/27) ♡
• The 2-Oxoglutarate Carrier Is S-Nitrosylated in the Spinal Cord of G93A Mutant hSOD1 Mice Resulting in Disruption of Mitochondrial Glutathione Transport. (2022/12/27) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Remodeling of astrocyte secretome in amyotrophic lateral sclerosis: uncovering novel targets to combat astrocyte-mediated toxicity. (2022/12/26) ♡
• Multiple pathways of lipid dysregulation in amyotrophic lateral sclerosis. (2022/12/26) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Filtered Cerebrospinal Fluid From Patients With Amyotrophic Lateral Sclerosis Displays an Altered Proteome and Affects Motor Phenotype in a Mouse Model. (2022/12/26) ♡
• Molecular Mechanisms of Aggregation of Canine SOD1 E40K Amyloidogenic Mutant Protein. (2022/12/24) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Esophageal Speech for a Patient with Amyotrophic Lateral Sclerosis Who Underwent a Central-part Laryngectomy to Prevent Aspiration: A Case Report. (2022/12/23) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. A Meta-Analysis Study of SOD1-Mutant Mouse Models of ALS to Analyse the Determinants of Disease Onset and Progression. (2022/12/22) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Inflammatory checkpoints in amyotrophic lateral sclerosis: From biomarkers to therapeutic targets. (2022/12/22) ♡
• TrkB signaling is correlated with muscular fatigue resistance and less vulnerability to neurodegeneration. (2022/12/22) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Could VGF and/or its derived peptide act as biomarkers for the diagnosis of neurodegenerative diseases: A systematic review. (2022/12/22) ♡
• Assessing the therapeutic impact of resveratrol in ALS SOD1-G93A mice with electrical impedance myography. (2022/12/22) ♡
• Feasibility, effectiveness, and safety of edoxaban administration through percutaneous endoscopic gastrostomy: 12-months follow up of the ORIGAMI study. (2022/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sexual Dimorphism in Neurodegenerative Diseases and in Brain Ischemia. (2022/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Vitamin D in Neurological Diseases. (2022/12/21) ♡
• Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice. (2022/12/21) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hsrω and Other lncRNAs in Neuronal Functions and Disorders in Drosophila. (2022/12/21) ♡
• DNA damage stress-induced translocation of mutant FUS proteins into cytosolic granules and screening for translocation inhibitors. (2022/12/20) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dysregulated Expression of Transposable Elements in TDP-43(M337V) Human Motor Neurons That Recapitulate Amyotrophic Lateral Sclerosis In Vitro. (2022/12/19) ♡
• The role of oxidative stress in neurodegenerative diseases and potential antioxidant therapies. (2022/12/19) ♡

↑ Back to top

codex.care does not provide medical advice. Always discuss symptoms, medication, and treatment choices with your own healthcare provider.