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Alpha-1 antitrypsin deficiency

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest Level of Evidence Only (35)Meta-analysis (8)Treatment guideline (5)Phase 3 study (8)Randomized trial (8)Systematic review (6)Clinical Trial (169)Review article (176)Early study (phase 1 or 2) (18)Case report (114)Laboratory or animal study (26)Commentary or editorial (90)Retracted publication (1) Only studies currently recruiting participants (28)

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Publications and studies (1172)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Liver disease in the older child. (2020/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-1 antitrypsin deficiency: an update on clinical aspects of diagnosis and management. (2020/10/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Combined liver-kidney transplantation for rare diseases. (2020/10/27) ♡
• The structural basis for Z α(1)-antitrypsin polymerization in the liver. (2020/10/21) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Modernising case finding for α(1)-antitrypsin deficiency by DNA sequencing of COPD patients. (2020/10/15) ♡
• Trends in Diagnosis of Alpha-1 Antitrypsin Deficiency Between 2015 and 2019 in a Reference Laboratory. (2020/10/07) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Alteration in angiotensin-converting enzyme 2 by PM(1) during the development of emphysema in rats. (2020/10/05) ♡
• Comorbidity Associations with AATD Among Commercially Insured and Medicare Beneficiaries with COPD in the US. (2020/10/05) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Bench to Bedside and Back: The Evolving Story of Alpha-1 Antitrypsin Deficiency. (2020/10/01) ♡
• Distinct anti-inflammatory properties of alpha1-antitrypsin and corticosteroids reveal unique underlying mechanisms of action. (2020/10/01) ♡
• [Screening for alpha1-antitrypsin deficiency using dried blood spot: Assessment of the first 20 months]. (2020/10/01) ♡
• Clinical outcomes and survival following lung transplantation in patients with Alpha-1 antitrypsin deficiency. (2020/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neutrophilic Infiltrates in Panniculitis: Comprehensive Review and Diagnostic Algorithm Proposal. (2020/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Severe Nocardia pneumonia in an immunocompromised patient with alpha-1 antitrypsin deficiency. (2020/09/24) ♡
• Evaluation of the Small Airways in Patients with Chronic Obstructive Pulmonary Disease and Alpha-1 Antitrypsin Deficiency. (2020/09/24) ♡
• Medical costs of Alpha-1 antitrypsin deficiency-associated COPD in the United States. (2020/09/23) ♡
• A Data-Driven Approach to Carrier Screening for Common Recessive Diseases. (2020/09/22) ♡
• CHOP and c-JUN up-regulate the mutant Z α(1)-antitrypsin, exacerbating its aggregation and liver proteotoxicity. (2020/09/18) ♡
• Correction to: Alpha-1 Antitrypsin Deficiency: a Rare Disease? (2020/09/12) ♡
• Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo. (2020/09/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Methods of Purification and Application Procedures of Alpha1 Antitrypsin: A Long-Lasting History. (2020/09/02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prevalence of Alpha-1 Antitrypsin Deficiency in COPD Patients in Argentina. The DAAT.AR Study. (2020/09/01) ♡
• Engineering synthetic breath biomarkers for respiratory disease. (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-1 Antitrypsin Deficiency Associated COPD. (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. New Directions in Pulmonary Gene Therapy. (2020/09/01) ♡
• Obesity related lung complications and a possible phytochemical therapeutic solution. (2020/09/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Geographical Overlap Between Alpha-1 Antitrypsin Deficiency and COVID-19 Infection in Italy: Casual or Causal? (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gene Therapy in Rare Respiratory Diseases: What Have We Learned So Far? (2020/08/08) ♡
• Gene therapy for alpha 1-antitrypsin deficiency with an oxidant-resistant human alpha 1-antitrypsin. (2020/08/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Vanishing Lung Syndrome: An Idiopathic Bullous Emphysema Mimicking Pneumothorax. (2020/08/06) ♡
• Nonfasted Liver Stiffness Correlates with Liver Disease Parameters and Portal Hypertension in Pediatric Cholestatic Liver Disease. (2020/08/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha1-Antitrypsin Deficiency: A Cause of Chronic Liver Disease. (2020/08/01) ♡
• The Importance of Reference Centers and Registries for Rare Diseases: The Example of Alpha-1 Antitrypsin Deficiency. (2020/08/01) ♡
• [New aspects of the development of liver diseases – with special regard to the role of autophagy and microRNA]. (2020/08/01) ♡
• Intrahepatic heteropolymerization of M and Z alpha-1-antitrypsin. (2020/07/23) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Prevalence of α(1)-antitrypsin PiZZ genotypes in patients with COPD in Europe: a systematic review. (2020/07/21) ♡
• A Highly Phenotyped Open Access Repository of Alpha-1 Antitrypsin Deficiency Pluripotent Stem Cells. (2020/07/14) ♡
• Accelerated (129) Xe MRI morphometry of terminal airspace enlargement: Feasibility in volunteers and those with alpha-1 antitrypsin deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Why is Disease Penetration So Variable? Role of Genetic Modifiers of Lung Function in Alpha-1 Antitrypsin Deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Non-Invasive Assessment and Management of Liver Involvement in Adults With Alpha-1 Antitrypsin Deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neutrophil Modulation in Alpha-1 Antitrypsin Deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Why is Disease Penetration so Variable in Alpha-1 Antitrypsin Deficiency? The Contribution of Environmental Factors. (2020/07/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Towards New Therapeutic Solutions for Alpha-1 Antitrypsin Deficiency: Role of the Alpha-1 Foundation. (2020/07/01) ♡
• The Alpha-1 Antitrypsin Polymer Load Correlates With Hepatocyte Senescence, Fibrosis Stage and Liver-Related Mortality. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Leveraging Population Genomics for Individualized Correction of the Hallmarks of Alpha-1 Antitrypsin Deficiency. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Feasibility of Aerosolized Alpha-1 Antitrypsin as a Therapeutic Option. (2020/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Update on Alpha-1 Antitrypsin Deficiency in Liver Disease. (2020/06/30) ♡
• Neonatal Cholestasis Over Time: Changes in Epidemiology and Outcome in a Cohort of 154 Patients From a Portuguese Tertiary Center. (2020/06/30) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Food Pyramid for Subjects with Chronic Obstructive Pulmonary Diseases. (2020/06/19) ♡
• A Stress Buffering Perspective on the Progression of Alpha-1 Antitrypsin Deficiency. (2020/05/01) ♡

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