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Thalassemia (severe form)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (53)Meta-analysis (12)Treatment guideline (1)Randomized trial (20)Systematic review (12)Phase 3 study (8)Clinical trial (379)Review article (138)Early study (phase 1 or 2) (18)Case report (134)Laboratory or animal research (17)Commentary or editorial (44)Retracted publication (2) Studies currently recruiting participants only (31)

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Publications (1159)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Prenatal screening for genetic disorders: Suggested guidelines for the Indian Scenario. (2017/12/01) ♡
• Allogeneic bone marrow transplant in the absence of cytoreductive conditioning rescues mice with β-thalassemia major. (2017/11/28) ♡
• BCL11A mRNA Targeting by miR-210: A Possible Network Regulating γ-Globin Gene Expression. (2017/11/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Is the Benefit-Risk Ratio for Patients with Transfusion-Dependent Thalassemia Treated by Unrelated Cord Blood Transplantation Favorable? (2017/11/20) ♡
• Degree of anemia, indirect markers of hemolysis, and vascular complications of sickle cell disease in Africa. (2017/11/16) ♡
• Cat-D: a targeted sequencing method for the simultaneous detection of small DNA mutations and large DNA deletions with flexible boundaries. (2017/11/16) ♡
• Partial Splenectomy in the treatment of an adult with β thalassemia intermedia: A case report. (2017/11/11) ♡
• [Epidemiological, clinical and hematological profiles of homozygous sickle cell disease during the intercritical period among children in Ziguinchor, Senegal]. (2017/11/07) ♡
• Prevalences of inherited red blood cell disorders in pregnant women of different ethnicities living along the Thailand-Myanmar border. (2017/11/02) ♡
• Carotid Doppler ultrasonography as a screening tool of early atherosclerotic changes in children and young adults with β-thalassemia major. (2017/11/01) ♡
• Dietary nonheme iron is equally bioavailable from ferritin or ferrous sulfate in thalassemia intermedia. (2017/11/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Hydroxyurea for lifelong transfusion-dependent β-thalassemia: A meta-analysis. (2017/11/01) ♡
• Iron overload assessment in β thalassemia major - is T2* Magnetic Resonance Imaging the answer? (2017/10/25) ♡
• Retinal nerve fiber layer thickness in children with β-thalassemia major. (2017/10/01) ♡
• Complications of Transfusion-Dependent β-Thalassemia Patients in Sistan and Baluchistan, South-East of Iran. (2017/10/01) ♡
• A Cross-Sectional Study of Glycemic Status and Zinc Level in Patients with Beta-Thalassemia Major. (2017/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. β-thalassemia minor, carbohydrate malabsorption and histamine intolerance. (2017/09/19) ♡
• Disease severity and slower psychomotor speed in adults with sickle cell disease. (2017/09/14) ♡
• A new red cell index and portable RBC analyzer for screening of iron deficiency and thalassemia minor in a Chinese population. (2017/09/05) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Prenatal Screening for Rare Co-Inheritance of HbE and β-Thalassaemia Traits in Western India. (2017/09/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Pneumococcal vaccination for splenectomized patients with thalassemia major in Indonesia. (2017/08/16) ♡
• Hepcidin suppression in β-thalassemia is associated with the down-regulation of atonal homolog 8. (2017/08/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Correlation of serum ferritin levels with hepatic MRI T2 and liver iron concentration in nontransfusion beta-thalassemia intermediate patients: A contemporary issue. (2017/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Silibinin: an old drug for hematological disorders. (2017/07/11) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Characterization of Two Novel Deletions Involving the 5' Region of the β-Globin Gene. (2017/07/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pseudoxanthoma Elasticum-Like in β-Thalassemia Major, a matter of α-Klotho and Parathyroid Hormone? (2017/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Coinheritance of α- and β-Thalassemia with a Novel Mutation (HBB: c.268_281delAGTGAGCTGCACTG) in a Chinese Family. (2017/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. First Report of the Rare IVS-II-705 (T>G) β-Thalassemia Mutation in a Chinese Family. (2017/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hb A(2)-Tianhe (HBD: c.323G>A): First Report in a Chinese Family with Normal Hb A(2)-β-Thalassemia Trait. (2017/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hb Hornchurch [β43(CD2)Glu→Lys; HBB: c.130G>A] Compromises the Molecular Diagnosis of β-Thalassemia in a Chinese Family. (2017/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Novel β-Thalassemia Insertion/Frameshift Mutation Between Codons 77/78 (p.Leu78Profs*13 or HBB: c.235_236insC) Observed in a Family in Bangladesh. (2017/07/01) ♡
• Prevalence of diabetes mellitus in Chinese children with thalassaemia major. (2017/06/01) ♡
• What could be the future of anemia management in chronic renal insufficiency? (2017/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hamartoma of the spleen (splenoma) with calcifications in a child with beta-thalassemia: A case report. (2017/05/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Liver transplantation from a deceased donor with β-thalassemia intermedia is not contraindicated: A case report. (2017/05/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chronic anemia and thyroid function. (2017/04/28) ♡
• KLF1 directly activates expression of the novel fetal globin repressor ZBTB7A/LRF in erythroid cells. (2017/04/25) ♡
• Cyclophosphamide improves engraftment in patients with SCD and severe organ damage who undergo haploidentical PBSCT. (2017/04/19) ♡
• Effects of iron overload, an iron chelator and a T-Type calcium channel blocker on cardiac mitochondrial biogenesis and mitochondrial dynamics in thalassemic mice. (2017/03/15) ♡
• Hepcidin detects iron deficiency in Sri Lankan adolescents with a high burden of hemoglobinopathy: A diagnostic test accuracy study. (2017/02/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Total Antioxidant Capacity in beta-thalassemia: A systematic review and meta-analysis of case-control studies. (2017/02/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Vitamin D supplementation for sickle cell disease. (2017/01/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Regulation of the Iron Homeostatic Hormone Hepcidin. (2017/01/17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Iron Chelation Therapy on Glucose Metabolism in Non-Transfusion-Dependent Thalassaemia. (2017/01/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Benefits of Curcumin Supplementation on Antioxidant Status in β-Thalassemia Major Patients: A Double-Blind Randomized Controlled Clinical Trial. (2017/01/01) ♡
• SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells. (2017/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A New Era for Hemoglobinopathies: More Than One Curative Option. (2017/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Sickle Cell Beta-Plus Thalassemia with Subcapsular Hematoma of the Spleen. (2017/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current and future alternative therapies for beta-thalassemia major. (2016/02/01) ♡
• Plastrum testudinis induces γ-globin gene expression through epigenetic histone modifications within the γ-globin gene promoter via activation of the p38 MAPK signaling pathway. (2013/06/01) ♡

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