# Nutrition in endometrial cancer
Weight and insulin resistance
Maintaining a healthy weight is receiving increasing attention in the treatment of endometrial cancer. Research suggests that overweight and obesity are associated with increased insulin resistance – a condition in which your body responds less well to the hormone insulin.
ResearchediPositive results in clinical studies, not yet standard treatment
This can affect how certain treatments work and how the disease progresses.
Weight management is therefore being discussed in an increasing number of treatment centres as part of care. This can happen in various ways – through changes to eating and exercise habits, guidance from a dietitian, or in some cases medication.
ResearchediPositive results in clinical studies, not yet standard treatment
Your oncology team and dietitian are best placed to discuss with you what applies personally to you.
Inflammatory markers and nutrition
Recent studies are looking at links between certain substances in your blood (inflammatory markers and nutritional factors) and how your body responds to hormone treatments.
ResearchediPositive results in clinical studies, not yet standard treatment
These studies are still in an exploratory phase and do not yet lead to concrete nutritional recommendations for individual patients. The aim is to be better able to assess in the future how someone's body responds to treatment, possibly with the help of nutritional data.
Nutrition after surgery
After a hysterectomy (removal of the uterus), some patients may experience constipation or disturbed bowel movement.
ResearchediPositive results in clinical studies, not yet standard treatment
Here food choices can play a role – for example sufficient fluid and fibre – but this is best discussed with your doctor or dietitian, as recommendations depend on your specific situation and any side effects of medication.
Metabolic health and long-term outcomes
Research suggests that metabolic health – including insulin resistance, inflammation and certain eating patterns – can influence the long-term outcomes of endometrial cancer.
ResearchediPositive results in clinical studies, not yet standard treatment
This is an active area of research, but at present there are no standard nutritional protocols that are generally recommended as part of cancer treatment itself.
Drug interactions
If you are receiving hormonal treatments (such as progestin for fertility-preserving treatment in early stage, or other hormonal therapies), certain foods and supplements may influence how your body absorbs and processes these medicines.
ResearchediPositive results in clinical studies, not yet standard treatment
It is important that you discuss with your doctor or pharmacist whether you want to use certain supplements or herbal teas – particularly grapefruit, St John's wort and certain vitamins can be important.
Practical nutritional points to consider
Many patients experience changes in appetite, taste, nausea or bowel function during and after treatment. This has more to do with side effects of treatment than with specific nutritional requirements for endometrial cancer itself. A dietitian can help you find strategies that work for your situation – for example small, regular meals, fluid intake, or adapted food textures.
Maintaining adequate energy and nutrients during and after treatment is important for your recovery, regardless of the specific food choices.
ProveniIncluded in official guidelines, or approved by EMA or FDA
A dietitian specialising in oncology can best guide you in this.
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_This information never replaces a doctor's judgment. Always discuss your situation with your own healthcare provider._