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Wilson's disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (159)Meta-analysis (51)Treatment guideline (12)Randomized controlled trial (58)Systematic review (25)Phase 3 study (13)Clinical trial (150)Review article (305)Early Study (Phase 1 or 2) (10)Case report (117)Laboratory or animal study (54)Commentary or editorial (34) Only studies currently recruiting participants (29)

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Publications and studies (2037)

• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Trientine Tetrahydrochloride Administered Once a Day for the First Line Treatment of Wilson's Disease Patients. (2026-08-05) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Phase I/II Clinical Study to Evaluate the Safety, Tolerability and Efficacy of LY-M003 Injection in Adult Patients With Wilson's Disease (2026-07-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Early Check: Expanded Screening in Newborns (2026-07-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natural History of Wilson Disease (2026-06-22) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 1/2/3 Study of UX701 Gene Therapy in Adults With Wilson Disease (2026-06-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prescreening Study to Identify Potential Wilson Disease Participants for Gene-Editing Clinical Trial (2026-05-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Real World Evidence Study in Subjects With Wilson's Disease (2026-04-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Patient Preference Study: Standard of Care Versus Once-daily Trientine Tetrahydrochloride (2026-04-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study. (2026-03-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Exchangeable and Relative Exchangeable Copper as an Alternative to 24-Hour Urinary Copper in Wilson's Disease Monitoring (2026-03-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Off Treatment Urinary Copper Excretion in Wilson Disease, Pilot Study (2026-03-05) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase I/II Study of VTX-801 in Adult Patients With Wilson's Disease (2026-01-30) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Clinical Study to Evaluate the Safety and Efficacy of LY-M003 Injection in Patients With Wilson Disease (2026-01-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Wilson's Disease Treated With D-Penicillamine: Characterization of Skin Damage Secondary to Treatment by Measuring Skin Elasticity (2026-01-23) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Clinical Study on the Treatment of Wilson Disease With ATP7B mRNA/LNP (DSL101) (2026-01-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Circadian Variation of Urinary Copper Excretion in Wilson Disease Patients (2026-01-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Institutional Registry of Rare Diseases (2026-01-14) ♡
• Bayesian scalar-on-tensor regression using the Tucker decomposition for sparse spatial modeling. (2025/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Rare Case of Shewanella putrefaciens Bacteremia Due to Cellulitis in a Patient With Chronic Lymphedema Without Marine Exposure. (2025/12/30) ♡
• FGFR signaling and neddylation facilitate SARS-CoV-2 infection by modulating interferon induction and viral entry, respectively. (2025/12/29) ♡
• Developing Synthetic Full-Length SARS-CoV-2 cDNAs and Reporter Viruses for High-Throughput Antiviral Drug Screening. (2025/12/27) ♡
• Drivers of prognosis and clinical trajectories differ between COVID and non-COVID acute hypoxic respiratory failure. (2025/12/26) ♡
• Discovery of newborn Wilson disease biomarkers via integrated next-generation sequencing and untargeted metabolomics. (2025/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Physiology and Diseases of the Hypothalamic-Pituitary Axis in the Elderly. (2025/12/25) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Gandou Bushen decoction ameliorates ovarian injury in murine hepatolenticular degeneration via the AGE/RAGE/NF-κB signaling pathway]. (2025/12/25) ♡
• The effects of introduced procedural errors on malaria rapid diagnostic test performance in a laboratory setting. (2025/12/24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Sex-specific placental transcriptome alterations in late-onset preeclampsia reveal male-biased immune and metabolic dysregulation. (2025/12/24) ♡
• Polyphenol-Enriched Fraction from Chestnut Shells as a Source of Bioactive Compounds for Friedreich Ataxia. (2025/12/24) ♡
• How do clinicians navigate end-of-life care with NIV/CPAP? A thematic analysis study. (2025/12/23) ♡
• Organ donation for research purposes: a qualitative focus group study on the views of donor families, transplant recipients and heart failure patients in the UK. (2025/12/23) ♡
• Individual and combined effects of indoor home exposures and ambient PM(2.5) during early life on childhood asthma in us birth cohort studies. (2025/12/23) ♡
• Prevalence and Risk Factors for Suicidal Ideation and Attempts Among Black LGBTQ+ Young Adults. (2025/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathogenesis of Type 2 Diabetes Mellitus. (2025/12/22) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. New insights into the effects of dissolution profiles on the pharmacokinetics of trientine dihydrochloride. (2025/12/22) ♡
• Characterising anticipatory postural adjustments in turning a comparison between older adults and people with Parkinson's disease. (2025/12/22) ♡
• Patterns of steroid use in patients with established rheumatoid arthritis commencing treatment with biologic or targeted synthetic DMARDs. (2025/12/22) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. O04 Mission EB -mesenchymal intravenous stromal cell infusions in children with recessive dystrophic epidermolysis bullosa: a randomised, double-blinded, placebo controlled, crossover trial. (2025/12/19) ♡
• Xenosiderophore transporter gene expression and clade-specific filamentation in Candida auris killifish (Aphanius dispar) infection. (2025/12/19) ♡
• Identification of Functional Genetic Components Modulating Toxicity Response to PFOS using Genome-wide CRISPR Screens in HepG2/C3A cells. (2025/12/19) ♡
• Establishing standardized transthoracic echocardiography reference ranges for mouse models: insights into the impact of anesthesia, sex, and age. (2025/12/19) ♡
• Lived Experiences of Patients and Care Providers in Focal Segmental Glomerular Sclerosis and IgA Nephropathy. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Neurohypophysis: Endocrinology of Vasopressin and Oxytocin. (2025/12/18) ♡
• Renal sarcomas in children and adolescents: a retrospective, multicenter cohort study. (2025/12/18) ♡
• Prostate cancer risk-associated single-nucleotide polymorphisms impact the conformational dynamics of prostate-specific antigen. (2025/12/17) ♡
• Analysis of tissue copper levels as a reliable diagnostic tool in paediatric liver disease. (2025/12/17) ♡
• Contrasting neonatal brain morphometry and its impact on neurodevelopmental outcome between preterm birth and congenital heart disease. (2025/12/17) ♡
• Occupation and Female Breast Cancer Mortality in South Africa: A Case-Control Study. (2025/12/17) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Mitochondrial dysfunction in Wilson disease: a systematic review and meta-analysis across human and animal models. (2025/12/17) ♡
• Extended poly(A) tails are a shared feature of herpesvirus mRNAs. (2025/12/16) ♡
• βc receptor antagonism mitigates sarcoidosis granuloma formation by targeting inflammatory signals and aberrant lipid metabolism. (2025/12/16) ♡

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