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Thalassemia (severe form)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (53)Meta-analysis (12)Treatment guideline (1)Randomized trial (20)Systematic review (12)Phase 3 study (8)Clinical trial (379)Review article (138)Early study (phase 1 or 2) (18)Case report (134)Laboratory or animal research (17)Commentary or editorial (44)Retracted publication (2) Studies currently recruiting participants only (31)

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Publications and studies (1521)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Effectiveness and tolerability of twice daily dosing of deferasirox in unresponsive and intolerant transfusion-dependent beta-thalassaemia patients: A narrative review. (2020/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Dengue Fever Associated Haemophagocytic Lymphohistiocytosis: A Report of Two Children. (2020/10/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Advances in gene therapy for β-thalassaemia and haemophilia based on the CRISPR/Cas9 technology]. (2020/10/20) ♡
• HV2 fragment mutations in β-thalassaemia patients and a new base pair insertion of high-altitude cases. (2020/10/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Human Pythiosis: Emergence of Fungal-Like Organism. (2020/10/01) ♡
• Correlation Of Serum Ferritin With Haemoglobin A2 Level In Beta Thalassaemia Traits. (2020/10/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. COVID-19 and thalassaemia beta major in splenectomized patient: Clinical case progression and literature review. (2020/09/12) ♡
• The relationships between pancreatic T2* values and pancreatic iron loading with cardiac dysfunctions, hepatic and cardiac iron siderosis among Egyptian children and young adults with β-thalassaemia major and sickle cell disease: a cross-sectional study. (2020/09/09) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. No differences in haemostatic and endothelial activations between haploidentical and matched-donor haematopoietic stem cell transplantation in thalassaemia disease. (2020/09/04) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. First Report of a Coincidental Discovery of Hb Antibes-Juan-Les-Pins (HBB: c.349_350insGTGTGCTGGCCC) in a Greek Woman. (2020/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Vitamin and mineral supplementation for β-thalassaemia during COVID-19 pandemic. (2020/08/18) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Dominant β-thalassaemia with unusually high Hb A(2) and Hb F caused by β(CD121(-G)) (HBB:c.364delG) in exon 3 of β-globin gene. (2020/08/01) ♡
• Effects of α-tocopherol on haemolysis and oxidative stress markers on red blood cells in β-thalassaemia major. (2020/08/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Blood pressure unknowns of sickle cell disease in children. (2020/08/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Challenges in transfusion and the role of Thalidomide in E-β-Thalassaemia-A case report. (2020/07/30) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Haemochromatosis in a β-thalassaemia minor patient with H63D homozygous mutation: A case report. (2020/07/12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluation of endocrine complications in beta-thalassaemia intermedia (β-TI): a cross-sectional multicentre study. (2020/07/01) ♡
• Efficacy of Dichlorophenolindophenol (DCIP) as Screening Test for Hb E: Revisited. (2020/07/01) ♡
• Body Composition in Egyptian Children With Transfusion-dependent Thalassaemia: The Impact of Nutrition and Metabolic Profile. (2020/07/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Case series of HbQ-India, a rare alpha globin variant in a referral laboratory setting in South India. (2020/07/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pellagra Disease in a Haemodialysis Patient. (2020/07/01) ♡
• Mean corpuscular volume/mean corpuscular haemoglobin values are not reliable predictors of the β-thalassaemia carrier status among healthy diverse populations of Himachal Pradesh, India. (2020/07/01) ♡
• Letter to the Editor: Boron enhances the antiviral activity of the curcumin against SARS-CoV-2. (2020/07/01) ♡
• The effects of iron overload, insulin resistance and oxidative stress on metabolic disorders in patients with β-thalassaemia major. (2020/06/03) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. HbE-Beta Thalassaemia with Moyamoya Syndrome: A Rare Association. (2020/06/01) ♡
• Genetic epidemiology of beta-thalassaemia in the Maldives: 23 years of a beta-thalassaemia screening program. (2020/05/30) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Effects of Alpha-Lipoic Acid Supplementation on Cardiovascular Disease Risk Factors in β-Thalassaemia Major Patients: A Clinical Trial Crossover Study. (2020/05/07) ♡
• Molecular and geographical heterogeneity of haemoglobinopathy mutations in Azerbaijanian populations. (2020/05/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Zinc supplementation improves glucose homeostasis in patients with β-thalassaemia major complicated with diabetes mellitus: A randomized controlled trial. (2020/05/01) ♡
• Food intolerance/malabsorption may occur in rare diseases. (2020/05/01) ♡
• National Prevalence of Micronutrient Deficiencies, Anaemia, Genetic Blood Disorders and Over- and Undernutrition in Omani Women of Reproductive Age and Preschool Children. (2020/05/01) ♡
• The Effects of Postprandial Resistance Exercise on Blood Glucose and Lipids in Prediabetic, Beta-Thalassaemia Major Patients. (2020/04/26) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Risk of thrombosis in patients with β-thalassaemia. (2020/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. HbA1C as a marker of retrograde glycaemic control in diabetes patient with co-existed beta-thalassaemia: A case report and a literature review. (2020/04/01) ♡
• Analysis of genotype distribution of thalassaemia and G6PD deficiency among Hakka population in Meizhou city of Guangdong Province. (2020/04/01) ♡
• Health state utilities associated with treatment for transfusion-dependent β-thalassemia. (2020/04/01) ♡
• Immunomodulator polyinosinic-polycytidylic acid enhances the inhibitory effect of 13-cis-retinoic acid on neuroblastoma through a TLR3-related immunogenic-apoptotic response. (2020/04/01) ♡
• Molecular prevalence and genotypes of human pegivirus-1 (HPgV-1) and SENV-like viruses among multiply transfused patients with beta-thalassemia. (2020/04/01) ♡
• Sickle cell disease in Germany: Results from a national registry. (2020/04/01) ♡
• Early development of decreased β-cell insulin secretion in children and adolescents with hemoglobin H disease and its relationship with levels of anemia. (2020/04/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Increased ferritin levels in non-transfusion-dependent β°-thalassaemia/HbE are associated with reduced CXCR2 expression and neutrophil migration. (2020/04/01) ♡
• Red Cell Indices in Screening of Thalassemia Trait During Antenatal Period. (2020/04/01) ♡
• Promising Response to Thalidomide in Symptomatic β-Thalassemia. (2020/04/01) ♡
• Inadequate Pre-conception Counseling is a Major Challenge for Antenatal Management of β-Thalassemia: Experience from a Referral Centre in India. (2020/04/01) ♡
• Iron Overload Associated Endocrine Dysfunction Leading to Lower Bone Mineral Density in Thalassemia Major. (2020/04/01) ♡
• Regulators' Advice Can Make a Difference: European Medicines Agency Approval of Zynteglo for Beta Thalassemia. (2020/03/01) ♡
• HbS/β+ thalassemia: Really a mild disease? A National survey from the AIEOP Sickle Cell Disease Study Group with genotype-phenotype correlation. (2020/03/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Misdiagnosis of double heterozygous ε(G)γ((A)γδβ)(0)-thalassemia/β(++) thalassemia as homozygous β-thalassemia: A pitfall for molecular diagnostic laboratories. (2020/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Genetic disruption of KCC cotransporters in a mouse model of thalassemia intermedia. (2020/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular targets and therapeutic interventions for iron induced neurodegeneration. (2020/03/01) ♡

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