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Primary lateral sclerosis
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Publications and studies (2508)
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. When to Do No Harm. (2021/04/01) ♡
- Beta-synuclein in cerebrospinal fluid as an early diagnostic marker of Alzheimer's disease. (2021/04/01) ♡
- Cell-penetrating, antioxidant SELENOT mimetic protects dopaminergic neurons and ameliorates motor dysfunction in Parkinson's disease animal models. (2021/04/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Predictive fat mass equations for spinal muscular atrophy type I children: Development and internal validation. (2021/04/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Opportunities and challenges for the nanodelivery of green tea catechins in functional foods. (2021/04/01) ♡
- Nutrition for Patients with Amyotrophic Lateral Sclerosis #411. (2021/04/01) ♡
- Dried Blood Spot Screening System for Spinal Muscular Atrophy with Allele-Specific Polymerase Chain Reaction and Melting Peak Analysis. (2021/04/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case Report on Robot-Aided Gait Training in Primary Lateral Sclerosis Rehabilitation: Rationale, Feasibility and Potential Effectiveness of a Novel Rehabilitation Approach. (2021/04/01) ♡
- [Chaihu Guizhi decoction produces antidepressant-like effects via sirt1-p53 signaling pathway]. (2021/03/25) ♡
- [Changing medical care for amyotrophic lateral sclerosis patients and cause of death - review of muscular dystrophy wards (1999-2013)]. (2021/03/25) ♡
- Alterations of mesenchymal stromal cells in cerebrospinal fluid: insights from transcriptomics and an ALS clinical trial. (2021/03/18) ♡
- Early advance care planning in amyotrophic lateral sclerosis patients: results of a systematic intervention by a palliative care team in a multidisciplinary management programme - a 4-year cohort study. (2021/03/18) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The Proteomics Study of Compounded HFE/TF/TfR2/HJV Genetic Variations in a Thai Family with Iron Overload, Chronic Anemia, and Motor Neuron Disorder. (2021/03/01) ♡
- Genetic investigation of amyotrophic lateral sclerosis patients in south Italy: a two-decade analysis. (2021/03/01) ♡
- Delayed onset of inherited ALS by deletion of the BDNF receptor TrkB.T1 is non-cell autonomous. (2021/03/01) ♡
- Correlation of Pulmonary Function to Novel Radiographic Parameters of Collapsing Parasol Deformity in Spinal Muscular Atrophy. (2021/03/01) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Spinal motor neuron loss occurs through a p53-and-p21-independent mechanism in the Smn(2B/-) mouse model of spinal muscular atrophy. (2021/03/01) ♡
- Longitudinal changes in network homogeneity in presymptomatic C9orf72 mutation carriers. (2021/03/01) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. Impact of the COVID-19 pandemic on a cohort of ALS patients in Catalonia. (2021/03/01) ♡
- Nusinersen treatment of older children and adults with spinal muscular atrophy. (2021/03/01) ♡
- Bone Mineral Density and Body Composition in Males with Motor Neuron Disease: A Study from Teaching Hospital in Southern Part of India. (2021/03/01) ♡
- Emerging Evidence Highlighting the Importance of Redox Dysregulation in the Pathogenesis of Amyotrophic Lateral Sclerosis (ALS). (2021/02/18) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Retrograde Mitochondrial Transport Is Essential for Organelle Distribution and Health in Zebrafish Neurons. (2021/02/17) ♡
- Cross-Comparison of Human iPSC Motor Neuron Models of Familial and Sporadic ALS Reveals Early and Convergent Transcriptomic Disease Signatures. (2021/02/17) ♡
- Measuring coping in people with amyotrophic lateral sclerosis using the Coping Index-ALS: A patient derived, Rasch compliant scale. (2021/02/15) ♡
- Cardiovascular comorbidities in amyotrophic lateral sclerosis. (2021/02/15) ♡
- Commentary or editorialiAn expert's opinion or commentary, not new research. From COVID-19 to ALS: Looking Beyond Just Black and White. (2021/02/09) ♡
- Comparison of Phenotypic Characteristics and Prognosis Between Black and White Patients in a Tertiary ALS Clinic. (2021/02/09) ♡
- Neuron type-specific increase in lamin B1 contributes to nuclear dysfunction in Huntington's disease. (2021/02/05) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Brain Stimulation as a Therapeutic Tool in Amyotrophic Lateral Sclerosis: Current Status and Interaction With Mechanisms of Altered Cortical Excitability. (2021/02/05) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A novel hypothesis on metal dyshomeostasis and mitochondrial dysfunction in amyotrophic lateral sclerosis: Potential pathogenetic mechanism and therapeutic implications. (2021/02/05) ♡
- ALSUntangled 55: vitamin E (α-tocopherol). (2021/02/01) ♡
- Pre-diagnostic plasma lipid levels and the risk of amyotrophic lateral sclerosis. (2021/02/01) ♡
- The cutaneous silent period in motor neuron disease. (2021/02/01) ♡
- The M1311V variant of ATP7A is associated with impaired trafficking and copper homeostasis in models of motor neuron disease. (2021/02/01) ♡
- Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natural history of Type 2 and 3 spinal muscular atrophy: 2-year NatHis-SMA study. (2021/02/01) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recent developments on PET radiotracers for TSPO and their applications in neuroimaging. (2021/02/01) ♡
- Converging integration between ascending proprioceptive inputs and the corticospinal tract motor circuit underlying skilled movement control. (2021/02/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acupuncture for Managing Amyotrophic Lateral Sclerosis. (2021/02/01) ♡
- Motor control and cognition deficits associated with protein carbamoylation in food (cassava) cyanogenic poisoning: Neurodegeneration and genomic perspectives. (2021/02/01) ♡
- Feeding difficulties in children and adolescents with spinal muscular atrophy type 2. (2021/02/01) ♡
- Is Exposure to BMAA a Risk Factor for Neurodegenerative Diseases? A Response to a Critical Review of the BMAA Hypothesis. (2021/02/01) ♡
- Risk of Amyotrophic Lateral Sclerosis and Exposure to Particulate Matter from Vehicular Traffic: A Case-Control Study. (2021/01/22) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Enhanced GABAergic Inhibition of Cholinergic Interneurons in the zQ175(+/-) Mouse Model of Huntington's Disease. (2021/01/20) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Relationship between Body Composition, Fatty Acid Metabolism and Diet in Spinal Muscular Atrophy. (2021/01/20) ♡
- Hypermetabolism is a reality in amyotrophic lateral sclerosis compared to healthy subjects. (2021/01/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Searching Far and Genome-Wide: The Relevance of Association Studies in Amyotrophic Lateral Sclerosis. (2021/01/14) ♡
- Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Non-genetic risk and protective factors and biomarkers for neurological disorders: a meta-umbrella systematic review of umbrella reviews. (2021/01/13) ♡
- Modeling Poliovirus Infection Using Human Engineered Neural Tissue Enriched With Motor Neuron Derived From Embryonic Stem Cells. (2021/01/06) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Communication skills among children with spinal muscular atrophy type 1: A parent survey. (2021/01/02) ♡
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