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Primary lateral sclerosis
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Publications and studies (2510)
- Feasibility, effectiveness, and safety of edoxaban administration through percutaneous endoscopic gastrostomy: 12-months follow up of the ORIGAMI study. (2022/12/22) ♡
- Revised Hammersmith Scale for spinal muscular atrophy: Inter and intra-rater reliability and agreement. (2022/12/21) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Acacetin alleviates neuroinflammation and oxidative stress injury via the Nrf2/HO-1 pathway in a mouse model of spinal cord injury. (2022/12/21) ♡
- Sex and HDAC4 Differently Affect the Pathophysiology of Amyotrophic Lateral Sclerosis in SOD1-G93A Mice. (2022/12/21) ♡
- Antizyme Inhibitor 2-Deficient Mice Exhibit Altered Brain Polyamine Levels and Reduced Locomotor Activity. (2022/12/21) ♡
- Utility estimations of different health states of patients with type I, II, and III spinal muscular atrophy in China: A mixed approach study with patient and proxy-reported data. (2022/12/20) ♡
- Comprehensive profile and natural history of pediatric patients with spinal muscular atrophy: A large retrospective study from China. (2022/12/20) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dysregulated Expression of Transposable Elements in TDP-43(M337V) Human Motor Neurons That Recapitulate Amyotrophic Lateral Sclerosis In Vitro. (2022/12/19) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Integrative Meta-Analysis of Huntington's Disease Transcriptome Landscape. (2022/12/16) ♡
- Communication of the Diagnosis of Spinal Muscular Atrophy in the Views of Patients and Family Members, a Qualitative Analysis. (2022/12/16) ♡
- Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons. (2022/12/16) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Connexin 30 Deficiency Ameliorates Disease Progression at the Early Phase in a Mouse Model of Amyotrophic Lateral Sclerosis by Suppressing Glial Inflammation. (2022/12/16) ♡
- Network-based approach for targeting human kinases commonly associated with amyotrophic lateral sclerosis and cancer. (2022/12/16) ♡
- AHNAK-modified microbubbles for the intracranial delivery of triptolide: In-vitro and in-vivo investigations. (2022/12/15) ♡
- Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo. (2022/12/15) ♡
- Telomere length analysis in amyotrophic lateral sclerosis using large-scale whole genome sequence data. (2022/12/15) ♡
- Markers of blood-brain barrier disruption increase early and persistently in COVID-19 patients with neurological manifestations. (2022/12/15) ♡
- Spinal Muscular Atrophy: A New Frontier but the Same Old Boundaries. (2022/12/15) ♡
- Spinal Irisin Gene Delivery Attenuates Burn Injury-Induced Muscle Atrophy by Promoting Axonal Myelination and Innervation of Neuromuscular Junctions. (2022/12/14) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanisms of Autoimmune Cell in DA Neuron Apoptosis of Parkinson's Disease: Recent Advancement. (2022/12/14) ♡
- Specific Post-Translational Modifications of VDAC3 in ALS-SOD1 Model Cells Identified by High-Resolution Mass Spectrometry. (2022/12/13) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. High Dose Pharmaceutical Grade Biotin (MD1003) Accelerates Differentiation of Murine and Grafted Human Oligodendrocyte Progenitor Cells In Vivo. (2022/12/12) ♡
- Identification of DOT1L inhibitor in a screen for factors that promote dopaminergic neuron survival. (2022/12/12) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Development of a Nanoparticle-Based Approach for the Blood-Brain Barrier Passage in a Murine Model of Amyotrophic Lateral Sclerosis. (2022/12/10) ♡
- Protocol paper: kainic acid excitotoxicity-induced spinal cord injury paraplegia in Sprague-Dawley rats. (2022/12/09) ♡
- c-Abl Regulates the Pathological Deposition of TDP-43 via Tyrosine 43 Phosphorylation. (2022/12/08) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sensory Involvement in Amyotrophic Lateral Sclerosis. (2022/12/08) ♡
- Fatty acids derived from the probiotic Lacticaseibacillus rhamnosus HA-114 suppress age-dependent neurodegeneration. (2022/12/07) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Rapidly Progressive Frontotemporal Dementia With Amyotrophic Lateral Sclerosis in an Elderly Female. (2022/12/04) ♡
- Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Protective effect of isoflurane preconditioning on neurological function in rats with HIE. (2022/12/03) ♡
- Neural mechanisms underlying peripheral facial nerve palsy: A protocol for systematic review and meta-analysis of neuroimaging studies. (2022/12/02) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Osteomyelitis Possibly Caused by Exfoliation of Primary Teeth in a Patient with Osteopetrosis. (2022/12/02) ♡
- Effectiveness of herbal medicine on patients with amyotrophic lateral sclerosis: Analysis of the PRO-ACT data using propensity score matching. (2022/12/01) ♡
- Characteristics of Dysphagia Based on the Type of ALS in Korean Patients Evaluated Using Videofluoroscopic Study: A Retrospective Analysis. (2022/12/01) ♡
- Appetite and quality of life in amyotrophic lateral sclerosis: A scoping review. (2022/12/01) ♡
- Perceptions and Experiences of Nutrition Interventions in Individuals with Amyotrophic Lateral Sclerosis (ALS) and their Caregivers. (2022/12/01) ♡
- COVID-19 and the risk of Alzheimer's disease, amyotrophic lateral sclerosis, and multiple sclerosis. (2022/12/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Novel association of gluten sensitivity with immune-mediated neuromuscular syndrome in a dog. (2022/12/01) ♡
- Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Types and Concentrations of Blood-Based Biomarkers in Adults With Peripheral Neuropathies: A Systematic Review and Meta-analysis. (2022/12/01) ♡
- Rapidly and slowly progressive neuromuscular disease: differences in pulmonary function, respiratory tract infections and response to lung volume recruitment therapy (LVR). (2022/12/01) ♡
- Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case Report on a Young Male Taking Methylphenidate With Fasciculations and Dysphagia: Correlation or Causation? (2022/12/01) ♡
- Carrier frequency of Spinal muscular atrophy in individuals of a reproductive age group from North India. (2022/12/01) ♡
- [Multidisciplinary care and therapeutic advances in amyotrophic lateral sclerosis]. (2022/12/01) ♡
- Relationship between freshwater harmful algal blooms and neurodegenerative disease incidence rates in South Korea. (2022/11/26) ♡
- Dysregulation of Gene Expressions in Multiple Sclerosis: TNFSF13B and Other Candidate Genes. (2022/11/25) ♡
- [The role of steroid hormones in the neurodegenerative diseases]. (2022/11/23) ♡
- Mild dysphagia does not influence survival in ventilated amyotrophic lateral sclerosis patients. (2022/11/15) ♡
- Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ketogenic Diet: An Effective Treatment Approach for Neurodegenerative Diseases. (2022/11/15) ♡
- PCR-Based Screening of Spinal Muscular Atrophy for Newborn Infants in Hyogo Prefecture, Japan. (2022/11/14) ♡
- [GAO Wei-bin's clinical experience in treatment of medulla oblongata paralysis with nape acupuncture]. (2022/11/12) ♡
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