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Multiple sclerosis (progressive)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchEvidence of the highest level only (104)Meta-analysis (24)Treatment guideline (1)Randomized trial (43)Systematic review (21)Phase 3 Study (15)Clinical trial (370)Review article (234)Early study (phase 1 or 2) (22)Case report (83)Laboratory or animal study (21)Commentary or editorial (19) Studies currently recruiting participants only (33)

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Publications and studies (1542)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. "Selfie" Videos: A Novel, Patient-centered, Comprehensive Approach to Measuring Function in MS (2025-10-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Serum Neurofilaments and GFAP in Atypical Multiple Sclerosis (2025-09-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis (2025-09-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Role of Microglia in the Pathogenesis of Progressive Multiple Sclerosis (2025-09-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Real-world Study About the Impact of Siponimod Treatment on Secondary Progressive Multiple Sclerosis Patients in Russia (2025-09-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ChariotMS - Cladribine to Halt Deterioration in People With Advanced Multiple Sclerosis (2025-09-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. SIZOMUS Safety of Ixazomib Targeting Plasma Cells in Multiple Sclerosis (2025-09-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Allogeneic Mesenchymal Stem Cell-Derived Exosome Therapy for Progressive Multiple Sclerosis (2025-08-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Expanded Access to Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis (2025-08-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PET Study of PIPE-791 in Healthy Volunteers and Volunteers With PrMS and IPF (2025-08-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Non-Interventional Pilot Study to Explore the Role of Gut Flora in Disease (2025-07-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Neuropsychological Management of Multiple Sclerosis: Benefits of a Computerised Semi-autonomous At-home Cognitive Rehabilitation Programme (2025-07-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Metformin Treatment in Progressive Multiple Sclerosis (2025-07-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ABA-101 in Participants With Progressive Multiple Sclerosis (2025-07-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Nonrelapsing Secondary Progressive Multiple Sclerosis (NRSPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (HERCULES) (2025-07-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Simvastatin in Secondary Progressive Multiple Sclerosis (2025-07-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Metformin Add-on Clinical Study in Multiple Sclerosis to Evaluate Brain Remyelination And Neurodegeneration (2025-06-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Intrathecal Administration of Autologous Mesenchymal Stem Cell-derived Neural Progenitors (MSC-NP) in Progressive Multiple Sclerosis (2025-06-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Nasal Foralumab in Patients With Non-Active Secondary Progressive Multiple Sclerosis (2025-06-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Intermediate-Size Patient Population Expanded Access: Foralumab in Non-Active Secondary Progressive MS Patients (2025-06-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cladribine Tablets as an Exit Therapy Strategy (2025-06-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis (2025-05-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Assess the Efficacy of Mayzent on Microglia in Secondary Progressive Multiple Sclerosis (2025-05-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. TOPIK Study: A Study to Report Progressive Multifocal Leukoencephalopathy and Other Serious Opportunistic Infections in Natalizumab Treated Participants (2025-05-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of NG01 Cell Therapy in Secondary Progressive Multiple Sclerosis (2025-05-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. IDP-023 g-NK Cells Plus Ocrelizumab in Patients With Progressive Multiple Sclerosis (2025-04-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Allogeneic Hematopoietic Cell Transplantation for Primary Progressive Multiple Sclerosis (2025-03-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Rehabilitative Protocols in Progressive Multiple Sclerosis Treated with Anti CD20 Monoclonal Antibodies (2025-03-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NYSCF Scientific Discovery Biobank (2025-03-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Lipoic Acid for Progressive Multiple Sclerosis (MS) (2025-03-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effect of Variance on Error Correction During Coupling (2025-02-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cognitive Reserve-building Activities in Multiple Sclerosis (2025-02-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ACTH in Progressive Forms of MS (2025-02-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. KYSA-7: A Study of Anti-CD19 CAR T-Cell Therapy, in Subjects With Refractory Primary and Secondary Progressive Multiple Sclerosis (2025-01-13) ♡
• Factors affecting fatigue progression in multiple sclerosis patients. (2024/12/30) ♡
• A 50-year data-driven model of disability and lesion load trajectories in progressive multiple sclerosis. (2024/12/27) ♡
• Prognostic Value of CXCL13, CCL11, and CCL20 Chemokines in Multiple Sclerosis. (2024/12/27) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Marburg variant of multiple sclerosis: A young women case report. (2024/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of CXCL12/CXCR4/CXCR7 axis in cognitive impairment associated with neurodegenerative diseases. (2024/12/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rationale for phosphodiesterase-4 inhibition as a treatment strategy for interstitial lung diseases associated with rheumatic diseases. (2024/12/23) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Bilateral Reversible Corneal Edema as a Novel Side-Effect of Levetiracetam - A Case Report. (2024/12/23) ♡
• Selective retinoid X receptor agonism promotes functional recovery and myelin repair in experimental autoimmune encephalomyelitis. (2024/12/21) ♡
• Workplace and social support, treatment satisfaction, and their impact on quality of life in Swedish women with multiple sclerosis: a cross-sectional survey study. (2024/12/20) ♡
• Barriers to clinical follow-up visits in multiple sclerosis: A nationwide register-based study. (2024/12/18) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Combined Use of Intranasal Methylprednisolone and Allopregnanolone: Revisiting Anti-inflammatory and Remyelinating Treatment in a Murine Model of Multiple Sclerosis. (2024/12/18) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Brain organoid methodologies to explore mechanisms of disease in progressive multiple sclerosis. (2024/12/18) ♡
• In-depth analysis of serum antibodies against Epstein-Barr virus lifecycle proteins, and EBNA1, ANO2, GlialCAM and CRYAB peptides in patients with multiple sclerosis. (2024/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring the Role of Axons in ALS from Multiple Perspectives. (2024/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Role and Diagnostic Significance of Apolipoprotein D in Selected Neurodegenerative Disorders. (2024/12/14) ♡
• Tyro3 and Gas6 are associated with white matter and myelin integrity in multiple sclerosis. (2024/12/13) ♡

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