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Multiple sclerosis (progressive)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchEvidence of the highest level only (104)Meta-analysis (24)Treatment guideline (1)Randomized trial (43)Systematic review (21)Phase 3 Study (15)Clinical trial (370)Review article (234)Early study (phase 1 or 2) (22)Case report (83)Laboratory or animal study (21)Commentary or editorial (19) Studies currently recruiting participants only (33)

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Publications and studies (1542)

• Norma Latina Neuropsychological Evaluation in Individuals with Multiple Sclerosis and Its Relationship with Disability. (2025/11/21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natalizumab and fumarate treatment differentially modulate CD4+ T cell and B cell subtypes in multiple sclerosis patients without impacting durable COVID-19 vaccine responses. (2025/11/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Progressive Cerebral Atrophy and Cognitive Decline Without Cerebral Lesion in Neuromyelitis Optica Spectrum Disorder: A Case Report. (2025/11/16) ♡
• Demyelination-induced glutamatergic imbalance mediates hippocampal Hyperexcitability. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multiple sclerosis: a comprehensive review of pathophysiology and combined natural-synthetic therapeutic strategies. (2025/11/01) ♡
• Cross-sectional study on association of autoantibodies and organ involvement in systemic sclerosis patients. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring the therapeutic and rehabilitative role of transcranial magnetic stimulation in multiple sclerosis. (2025/11/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A review of multiple sclerosis: From pathophysiology to latest therapeutic advances. (2025/10/31) ♡
• [Heterogeneity in the regulation of cellular stress responses by FUS gene mutations associated with amyotrophic lateral sclerosis]. (2025/10/28) ♡
• Eomesodermin-expressing CD4 Th cells and association with multiple sclerosis progression and brain atrophy. (2025/10/27) ♡
• Mediterranean and MIND Dietary Patterns and Cognitive Performance in Multiple Sclerosis: A Cross-Sectional Analysis of the UK Multiple Sclerosis Register. (2025/10/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sex-Related Differences in Lifestyle Factors Affecting Multiple Sclerosis Susceptibility and Disease Progression. (2025/10/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Flavonoids and phenolic compounds: a promising avenue for neurodegenerative disease therapy. (2025/10/10) ♡
• Exploring the screening methods, prevalence, and risk factors of malnutrition in multiple sclerosis: A scoping review. (2025/10/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Precision Nutrition and Gut-Brain Axis Modulation in the Prevention of Neurodegenerative Diseases. (2025/09/26) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effects of cognitive rehabilitation and exercise on brain structure in progressive multiple sclerosis: results from the CogEx trial. (2025/09/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The IL-12 family cytokines in neurodegenerative diseases: dual roles in neurotoxicity and neuroprotection. (2025/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Preclinical Effects of Prolonged Intermittent Fasting in an Animal Model on the Development of Multiple Sclerosis Pathology. (2025/08/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Adipokines in multiple sclerosis: Immune dysregulation, neuroinflammation, and therapeutic opportunities. (2025/07/31) ♡
• The effectiveness of combining a home-based Digital motor Telerehabilitation program with conventional therapy in progressive multiple sclerosis: A study protocol for a multicenter, randomized controlled trial. (2025/07/23) ♡
• Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis. (2025/07/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Correlates of Processing Speed Change With Combined Cognitive Rehabilitation and Exercise in Progressive MS: Secondary Analysis of the CogEx Trial. (2025/07/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Iron-Status Indicators and HFE Gene Polymorphisms in Individuals with Amyotrophic Lateral Sclerosis: An Umbrella Review of Meta-analyses and Systematic Reviews. (2025/06/01) ♡
• The role of serum vitamins in mediating the effect of neurodegenerative diseases on subcortical brain volume. (2025/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. From prevention to management: Exploring the impact of diet on multiple sclerosis. (2025/05/14) ♡
• The Association Between Myokines, Inflammation, and Nutritional Status in Patients with Multiple Sclerosis. (2025/05/12) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: A case of subacute combined degeneration of the spinal cord associated with chronic atrophic gastritis, macrocytic anemia, and positive anti-sulfatide IgM and IgG antibodies. (2025/05/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rehabilitation of Women with Neurodegenerative Diseases. (2025/05/01) ♡
• An expert patient program for people living with multiple sclerosis improves knowledge and empowerment: a pre-test, post-test multicenter implementation study. (2025/04/29) ♡
• Myelopoiesis is temporally dynamic and is regulated by lifestyle to modify multiple sclerosis. (2025/04/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The role of Panax ginseng in neurodegenerative disorders: mechanisms, benefits, and future directions. (2025/04/15) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Examination of Anti-Inflammatory Effects After Propionate Supplementation in the R6/2 Mouse Model of Huntington's Disease. (2025/04/02) ♡
• Multiomics Approach Reveal Novel Insights in FUS Driven Juvenile Amyotrophic Lateral Sclerosis: A Family Quartet Analysis. (2025/04/01) ♡
• Atlas of Cerebrospinal Fluid Immune Cells Across Neurological Diseases. (2025/04/01) ♡
• Anti-JCV antibody index seroconversion in Turkish multiple sclerosis patients treated with natalizumab. (2025/04/01) ♡
• Dynamic 18 F-FDG PET to detect differences among patients with progressive and relapsing multiple sclerosis: a pilot study. (2025/04/01) ♡
• Increased White Matter Aerobic Glycolysis in Multiple Sclerosis. (2025/04/01) ♡
• Loss of Insight in Syndromes Associated with Frontotemporal Lobar Degeneration: Clinical and Imaging Features. (2025/04/01) ♡
• Recommendations for essential medicines for multiple sclerosis in low-resource settings. (2025/04/01) ♡
• The Barancik award lecture: Multi-disciplinary research will be the key to stop, restore, and end MS. (2025/04/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Markedly elevated cerebrospinal fluid white blood cell count in multiple sclerosis: How high is too high? (2025/04/01) ♡
• Ursolic acid derivatives improved clinical signs of experimental autoimmune encephalomyelitis by modulating central nervous system inflammation. (2025/04/01) ♡
• Effects of a Multimodal Lifestyle Intervention on Cardiometabolic Markers in People with Progressive Multiple Sclerosis: A Secondary Analysis of a Pilot Study. (2025/03/27) ♡
• Financial burden of out of pocket nonpharmacological therapies in an Austrian multiple sclerosis cohort. (2025/03/19) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Bile acid metabolites predict multiple sclerosis progression and supplementation is safe in progressive disease. (2025/03/14) ♡
• The Erythrocyte Fatty Acid Profile in Multiple Sclerosis Is Linked to the Disease Course, Lipid Peroxidation, and Dietary Influence. (2025/03/11) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. DNAJC30 Mutation in a Patient with Coexisting Leber's Hereditary Optic Neuropathy and Multiple Sclerosis (Harding's Syndrome): A Case Report. (2025/03/07) ♡
• Flexible Spline Models for Blinded Sample Size Reestimation in Event-Driven Clinical Trials. (2025/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Microglial suppression by myeloperoxidase inhibitor does not delay neurodegeneration in a mouse model of progressive multiple sclerosis. (2025/03/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Cryptococcal meningoencephalitis in a patient on immunomodulatory drug: A case report. (2025/03/01) ♡

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