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Multiple sclerosis (progressive)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchEvidence of the highest level only (104)Meta-analysis (24)Treatment guideline (1)Randomized trial (43)Systematic review (21)Phase 3 Study (15)Clinical trial (370)Review article (234)Early study (phase 1 or 2) (22)Case report (83)Laboratory or animal study (21)Commentary or editorial (19) Studies currently recruiting participants only (33)

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Publications and studies (1542)

• Methodologies of speech analysis for neurodegenerative diseases evaluation. (2019/02/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Economic Evaluation of Stem Cell Therapies in Neurological Diseases: A Systematic Review. (2019/02/01) ♡
• Plasma levels of soluble NCAM in multiple sclerosis. (2019/01/15) ♡
• The Role of Palliative Care in Chronic Progressive Neurological Diseases-A Survey Amongst Neurologists in the Netherlands. (2019/01/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathogenic Mechanisms Associated With Different Clinical Courses of Multiple Sclerosis. (2019/01/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Coexistence of Multiple Sclerosis and Alzheimer's disease: A review. (2019/01/01) ♡
• Impact of early diagnosis on clinical characteristics of an Italian sample of people with multiple sclerosis recruited online. (2019/01/01) ♡
• Treating the ineligible: Disease modification in people with multiple sclerosis beyond NHS England commissioning policies. (2019/01/01) ♡
• Peripapillary retinal nerve fiber layer thickness measured by optical coherence tomography in different clinical subtypes of multiple sclerosis. (2019/01/01) ♡
• Association Between IL7R Promoter Polymorphisms and Multiple Sclerosis in Turkish Population. (2019/01/01) ♡
• Protective and therapeutic role of Bilobalide in cuprizone-induced demyelination. (2019/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation. (2019/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effectiveness and safety of Rituximab in demyelinating diseases spectrum: An Italian experience. (2019/01/01) ♡
• Multiple Sclerosis Incidence and Prevalence Trends in the Province of Padua, Northeast Italy, 1965-2018. (2019/01/01) ♡
• Determinants of Deep Gray Matter Atrophy in Multiple Sclerosis: A Multimodal MRI Study. (2019/01/01) ♡
• Identifying Patients With Relapsing-Remitting Multiple Sclerosis Using Algorithms Applied to US Integrated Delivery Network Healthcare Data. (2019/01/01) ♡
• Aluminum in neurological disease - a 36 year multicenter study. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Molecular Mechanisms of Curcumin in Neuroinflammatory Disorders: A Mini Review of Current Evidences. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Interference of High Dose Biotin Supplementation with Thyroid Parameters in Immunoassays Utilizing the Interaction between Streptavidin and Biotin: a Case Report and Review of Current Literature. (2019/01/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Neurofilament Light Chain in Cerebrospinal Fluid and Blood as a Biomarker for Neurodegenerative Diseases: A Systematic Review and Meta-Analysis. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuroimaging in aging and neurologic diseases. (2019/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multiple Sclerosis. (2019/01/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. [The efficacy and safety of siponimod in the Russian population of patients with secondary progressive multiple sclerosis]. (2019/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. [Changes in the quality of life in patients with multiple sclerosis treated with ocrelizumab]. (2019/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Clinical case of levamisole-induced multifocal inflammatory leukoencephalopathy]. (2019/01/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Prevalence of Anti-JC Virus Antibody Seropositivity in Patients with Multiple Sclerosis: A Systematic Review and Meta-Analysis. (2019/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Investigation of Simvastatin in Secondary Progressive Multiple Sclerosis (2019-12-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Estriol Treatment in Multiple Sclerosis (MS): Effect on Cognition (2019-11-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety and Tolerability of Quetiapine in Multiple Sclerosis (2019-10-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Intrathecal Rituximab in Progressive Multiple Sclerosis (2019-10-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of Biomarkers of the Response to Biotine (2019-09-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Pilot Study of Lithium in Progressive Multiple Sclerosis (2019-09-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open-Label Study to Evaluate the Efficacy of ECP in Secondary Progressive Multiple Sclerosis (2019-08-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Efficacy of Autologous Mesenchymal Bone Marrow Stem Cells in Active & Progressive Multiple Sclerosis (2019-08-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparison of Clinical Effects of Rituximab and Glatiramer Acetate in Secondary Progressive Multiple Sclerosis Patients (2019-05-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PET Study in Multiple Sclerosis (2019-04-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis (2019-04-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Medication Usage and Patient Reported Outcomes Evaluation Via myBETAapp in Patients With Multiple Sclerosis Treated With Betaferon: a Pilot Study (2019-03-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparing Tolerability and Absorption of Racemic and R-lipoic Acid in Progressive Multiple Sclerosis (2019-03-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Trial of Idebenone in Primary Progressive Multiple Sclerosis (IPPoMS) (2019-03-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mitochondrial Dysfunction and Disease Progression (2019-02-20) ♡
• Ocrelizumab Depletes CD20⁺ T Cells in Multiple Sclerosis Patients. (2018/12/28) ♡
• Contactin-1 and contactin-2 in cerebrospinal fluid as potential biomarkers for axonal domain dysfunction in multiple sclerosis. (2018/12/24) ♡
• CSF and blood biomarkers in amyotrophic lateral sclerosis: protocol for a systematic review and meta-analysis. (2018/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Can We Design a Nogo Receptor-Dependent Cellular Therapy to Target MS? (2018/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hydrogen Sulfide: A Therapeutic Option in Systemic Sclerosis. (2018/12/19) ♡
• CSF-Progranulin and Neurofilament Light Chain Levels in Patients With Radiologically Isolated Syndrome-Sign of Inflammation. (2018/12/18) ♡
• Astrocyte-Mediated Neuromodulatory Regulation in Preclinical ALS: A Metadata Analysis. (2018/12/17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Rationale and design of a single-blind, randomised controlled trial of exercise training for managing learning and memory impairment in persons with multiple sclerosis. (2018/12/14) ♡
• CSF Neurofilament Light Chain Levels in Primary Progressive MS: Signs of Axonal Neurodegeneration. (2018/12/14) ♡

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