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Multiple system atrophy (MSA)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (38)Meta-analysis (10)Treatment guideline (2)Systematic review (14)Randomized trial (9)Phase 3 study (3)Clinical trial (478)Review article (236)Early-stage study (phase 1 or 2) (13)Case descriptions (78)Laboratory or animal research (22)Commentary or editorial (37)Retracted publication (2)Concerns have been raised (1) Studies currently recruiting participants only (34)

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Publications and studies (1558)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Muscle-Specific Multimodal AI for Sarcopenia Diagnosis (2026-03-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Skeletal Muscle Multi-omics Analysis and Risk Tailoring in Sudden Cardiac Death (2026-03-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. [18F]F-DOPA Imaging in Patients With Autonomic Failure (2026-03-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. UB-312 in Patients With Synucleinopathies (2026-03-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Reduction in Splanchnic Capacitance Contributes to Sympathetically Dependent Hypertension in Autonomic (2026-03-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of AOC 1001 in Adult Myotonic Dystrophy Type 1 (DM1) Patients (2026-03-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Facility-Based Multi-Modal Rehab vs. Home-Based Resistance Exercise for Quality of Life in Breast Cancer Survivors (2026-03-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Autologous Stem Cell Therapy in Patients With Multiple System Atrophy (2026-03-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, and Pharmacokinetics of Exidavnemab in Patients With Parkinson's Disease and Patients With Multiple System Atrophy (2026-03-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study in Participants With Duchenne Muscular Dystrophy Amenable to Exon 44 Skipping to Evaluate the Safety and Efficacy of ENTR-601-44 (2026-03-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Community Outreach for Palliative Engagement -- Parkinson Disease (2026-03-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Shanghai Clinical Cohort - Parkinson's Disease (Reserve) (2026-03-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. [18F] - FD17 PET Imaging of α-synuclein: A Clinical Study in α-synucleinopathy Patients (2026-03-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. MSA-01 in Multiple System Atrophy (2026-03-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Muscle Stem Cell Quality in Atrophy (2026-03-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of the Effect of (S)-Pindolol Benzoate (ACM-001.1) on Lean Body Mass (LBM) in Obese Patents During (PROACT 1), and Post-semaglutide Therapy (PROACT 2) (2026-02-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Real-world Study of Disease-modifying Therapy Treatment Outcomes in Patients With Spinal Muscular Atrophy (2026-02-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of ATX-01 in Participants With DM1 (2026-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Synaptic Loss in Multiple System Atrophy (2026-02-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Efficacy and Safety of Once Daily Mexiletine PR in Patients With Myotonic Dystrophy Type 1 and Type 2 (2026-02-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study on Artificial Intelligence-Based Facial and Speech-Related Patterns in Parkinson's Disease and Their Digital Biomarkers (2026-02-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. North American Mitochondrial Disease Consortium Patient Registry and Biorepository (NAMDC) (2026-02-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. GDNF Gene Therapy for Multiple System Atrophy (2026-01-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Feasibility Study Assessing the Effect of Carbidopa/Levodopa Ratio on Orthostatic Hypotension in Multiple System Atrophy - Parkinsonian Type and Parkinson Disease. (2026-01-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Facilitating Diagnostics and Prognostics of Parkinsonian Syndromes Using Neuroimaging (2026-01-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pre-Symptomatic Study of Intravenous Onasemnogene Abeparvovec-xioi in Spinal Muscular Atrophy (SMA) for Patients With Multiple Copies of SMN2 (2026-01-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Overnight Trials With Heat Stress in Autonomic Failure Patients With Supine Hypertension (2026-01-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Slowing Cognitive Decline in Alpha-synucleinopathies by Enhancing Physical Activity (2026-01-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The CurePSP Genetics Program (2026-01-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Does Recessive Optic Atrophy Due to WFS1 Exist? (2026-01-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase IIIb, Open-label, Multi-center Study to Evaluate Safety, Tolerability and Efficacy of OAV101 Administered Intrathecally to Participants With SMA Who Discontinued Treatment With Nusinersen or Risdiplam (2026-01-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Muscle Stimulation for Physical Function During Stem Cell Transplant (2026-01-02) ♡
• Inertial Agitation in an NMR Magnet: Real-Time Monitoring of Protein Aggregation at High Resolution. (2025/12/31) ♡
• MRI-derived atrophy in multiple system atrophy aligns with mitochondrial and glial gene expression patterns. (2025/12/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multiple system atrophy: advances in pathogenesis and emerging therapeutic strategies. (2025/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Should Neurogenic Supine Hypertension Be Treated? Insights from Hypertension-Mediated Organ Damage Studies-A Narrative Review. (2025/12/24) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Cutaneous α-Synuclein and Age Spots in Neurodegeneration: A Systematic Review and Testable Hypothesis. (2025/12/22) ♡
• Targeted antisense oligonucleotide treatment rescues developmental alterations in spinal muscular atrophy organoids. (2025/12/21) ♡
• Specific genetic and biological patterns underlying cortical morphological alterations in vascular cognitive impairment. (2025/12/20) ♡
• Interpretable machine learning for differentiating SCA3 and MSA-C using gait and postural features from wearable sensors. (2025/12/20) ♡
• Tremor in Parkinson's Disease. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Brain atrophy in autoimmune encephalitis: epidemiology, pathophysiology, clinical manifestations, treatment, and prognosis-an update. (2025/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A rare constellation of bilateral progressive visual and auditory loss in neurofibromatosis type 2: a multimodal diagnostic approach. (2025/12/18) ♡
• Nationwide Survey on the Characteristics and Treatment of Age-Related Vocal Fold Atrophy in Japan. (2025/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Research progress on enhanced recovery after posterior cruciate ligament reconstruction]. (2025/12/15) ♡
• Clinical and neuroimaging correlates of disease related gait patterns in patients with multiple system atrophy cerebellar type. (2025/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Hidden faces of alpha-synuclein: Cryo-EM revelation of fibril polymorphs driven by disease, mutations, and PTMs. (2025/12/14) ♡
• Charles Bonnet Syndrome. (2025/12/13) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Quantification of Neuromelanin as a Neuroimaging Biomarker for Parkinson's Disease. (2025/12/10) ♡
• Seed amplification of MSA alpha-synuclein aggregates preserves the biological and structural properties of brain-derived aggregates. (2025/12/10) ♡

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