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Multiple system atrophy (MSA)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (38)Meta-analysis (10)Treatment guideline (2)Systematic review (14)Randomized trial (9)Phase 3 study (3)Clinical trial (478)Review article (236)Early-stage study (phase 1 or 2) (13)Case descriptions (78)Laboratory or animal research (22)Commentary or editorial (37)Retracted publication (2)Concerns have been raised (1) Studies currently recruiting participants only (34)

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Publications and studies (1558)

• Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies. (2018/01/24) ♡
• Association analysis of SNP rs11868035 in SREBF1 with sporadic Parkinson's disease, sporadic amyotrophic lateral sclerosis and multiple system atrophy in a Chinese population. (2018/01/18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Idiopathic cerebellar ataxia (IDCA): Diagnostic criteria and clinical analyses of 63 Japanese patients. (2018/01/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Extensive Delayed Brain Atrophy after Resuscitation in a Patient with Multiple System Atrophy. (2018/01/15) ♡
• Recommendations of the Global Multiple System Atrophy Research Roadmap Meeting. (2018/01/09) ♡
• Familial Parkinson's point mutation abolishes multiple system atrophy prion replication. (2018/01/09) ♡
• The Bulbocavernosus Reflex in the Differential Diagnosis of Multiple System Atrophy with Predominant Parkinsonism and Parkinson's Disease. (2018/01/05) ♡
• 3-Hz postural tremor in multiple system atrophy cerebellar type (MSA-C)-a static posturography study. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Multiple system atrophy: experimental models and reality. (2018/01/01) ♡
• Ocular features of multiple system atrophy. (2018/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Altered gut microbiome and metabolome in patients with multiple system atrophy. (2018/01/01) ♡
• Cerebrospinal fluid levels of coenzyme Q10 are reduced in multiple system atrophy. (2018/01/01) ♡
• Serum microRNA expression profiling in patients with multiple system atrophy. (2018/01/01) ♡
• MR planimetry in neurodegenerative parkinsonism yields high diagnostic accuracy for PSP. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pathological Yawning, Laughing and Crying. (2018/01/01) ♡
• Effects of saffron and its constituents, crocin-1, crocin-2, and crocetin on α-synuclein fibrils. (2018/01/01) ♡
• A routinely used protein staining dye acts as an inhibitor of wild type and mutant alpha-synuclein aggregation and modulator of neurotoxicity. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Idiopathic REM sleep behaviour disorder and neurodegeneration - an update. (2018/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparison of dystonia between Parkinson's disease and atypical parkinsonism: The clinical usefulness of dystonia distribution and characteristics in the differential diagnosis of parkinsonism. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A review of structural brain abnormalities in Pallister-Killian syndrome. (2018/01/01) ♡
• Neuropsychological and clinical heterogeneity of cognitive impairment in patients with multiple system atrophy. (2018/01/01) ♡
• Measuring the Overall Rate of Protein Breakdown in Cells and the Contributions of the Ubiquitin-Proteasome and Autophagy-Lysosomal Pathways. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Functional MRI in Atypical Parkinsonisms. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. PET Molecular Imaging in Atypical Parkinsonism. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. SPECT Molecular Imaging in Atypical Parkinsonism. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Structural Imaging in Atypical Parkinsonism. (2018/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Neuroimaging Applications in Chronic Ataxias. (2018/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Treatment of Parkinson Disease and Multiple System Atrophy Using Intranasal Insulin. (2018-11-23) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PET Imaging Study of Neurochemical and Autonomic Disorders in Multiple System Atrophy (MSA) (2018-11-05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Exploit the Neural Source and the Feasibility of Transcranial Direct Current Stimulation for Freezing of Gait in Parkinson's Disease and Multiple System Atrophy (2018-10-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Power Over Pain (POP) Study (2018-10-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase I/II Study of PRO044 in Duchenne Muscular Dystrophy (DMD) (2018-10-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Contribution of Angiotensin II to Supine Hypertension in Autonomic Failure (2018-08-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tracking Neurodegeneration in Early Wolfram Syndrome (2018-07-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Turkish Version of The Measure of Processes of Care (MPOC) (2018-04-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Enhance Wellness for Individuals With Long-Term Physical Disabilities (2018-04-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. The Autonomic Nervous System and Obesity (2018-03-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Transcranial Duplex Scanning and Single Photon Emission Computer Tomography (SPECT) in Parkinsonian Syndromes (2018-02-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study About Efficacy and Safety to Treat Multi-System-Atrophy (2018-02-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Extension Study of BMN 044 in Duchenne Muscular Dystrophy (DMD) (2018-01-26) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Diffusion-weighted MRI distinguishes Parkinson disease from the parkinsonian variant of multiple system atrophy: A systematic review and meta-analysis. (2017/12/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Senile Depression with Somatization Symptoms and Insomnia is Diagnosed as Multiple System Atrophy: A Case Report. (2017/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Patterns of Retinal Ganglion Cell Damage in Neurodegenerative Disorders: Parvocellular vs Magnocellular Degeneration in Optical Coherence Tomography Studies. (2017/12/22) ♡
• Discovering the 3' UTR-mediated regulation of alpha-synuclein. (2017/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chronic organ failure in adult sickle cell disease. (2017/12/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Therapeutic approaches to target alpha-synuclein pathology. (2017/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Potential clinical utility of multiple system atrophy biomarkers. (2017/12/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Efficacy of fingolimod and interferon beta-1b on cognitive, MRI, and clinical outcomes in relapsing-remitting multiple sclerosis: an 18-month, open-label, rater-blinded, randomised, multicentre study (the GOLDEN study). (2017/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Therapeutic Potential of Ursolic Acid to Manage Neurodegenerative and Psychiatric Diseases. (2017/12/01) ♡
• Comparing abnormalities of amplitude of low-frequency fluctuations in multiple system atrophy and idiopathic Parkinson's disease measured with resting-state fMRI. (2017/11/30) ♡

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