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Multiple system atrophy (MSA)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (38)Meta-analysis (10)Treatment guideline (2)Systematic review (14)Randomized trial (9)Phase 3 study (3)Clinical trial (478)Review article (236)Early-stage study (phase 1 or 2) (13)Case descriptions (78)Laboratory or animal research (22)Commentary or editorial (37)Retracted publication (2)Concerns have been raised (1) Studies currently recruiting participants only (34)

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Publications and studies (1558)

• Changing trends in cancer incidence of upper aerodigestive tract and stomach in Japanese alcohol-dependent men (1993-2018). (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanisms of alpha-synuclein toxicity: An update and outlook. (2020/01/01) ♡
• Recommendations of the Polish Medical Society of Radiology and the Polish Society of Neurology for a protocol concerning routinely used magnetic resonance imaging in patients with multiple sclerosis. (2020/01/01) ♡
• [Informative value of ultrasound in the diagnosis of intraneural perineurioma]. (2020/01/01) ♡
• [Palliative care in Parkinson's disease and neurodegenerative diseases]. (2020/01/01) ♡
• [Parkinsonism-associated speech disorders]. (2020/01/01) ♡
• Progressive multifocal leukoencephalopathy lesion and brain parenchymal segmentation from MRI using serial deep convolutional neural networks. (2020/01/01) ♡
• [Clinical and biochemical heterogeneity of Parkinson's disease]. (2020/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A Review of Neuroimaging in Rare Neurodegenerative Diseases. (2020/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Phase 2 Study to Evaluate the Safety, Efficacy, Pharmacokinetics and Pharmacodynamics of PF-06252616 in Duchenne Muscular Dystrophy (2020-12-07) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Retinal Abnormalities as Biomarker of Disease Progression and Early Diagnosis of Parkinson Disease (2020-12-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cognitive Impairment In Frontotemporal Dementia (2020-11-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of an Investigational Drug, RO7239361 (BMS-986089), in Ambulatory Boys With DMD (2020-11-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. COVID-19 Pandemic and Parents of Disabled Children (2020-11-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of a Pre-Workout on Performance, Perceptual Responses, Energy Feelings and Muscular Properties, After a Training Microcycle in Adults. (2020-11-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cerebellar rTMS and Physical Therapy for Cerebellar Ataxia (2020-10-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Drug-drug Interaction Study With Risdiplam Multiple Dose and Midazolam in Healthy Participants (2020-10-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. PROgressive Supranuclear Palsy CorTico-Basal Syndrome Multiple System Atrophy Longitudinal Study UK (2020-10-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety, Tolerability, and Pharmacokinetics of Single and Multiple Doses of HT-100 in Duchenne Muscular Dystrophy (2020-09-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of CK-2127107 in Patients With Spinal Muscular Atrophy (2020-08-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects (2020-08-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Physiologic Volume and Atrophy of Brain and Spinal Cord Measured by Magnetic Resonance Imaging (2020-07-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Spinal Cord Analysis in Multiple Sclerosis (2020-03-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy, Safety, and Tolerability Rollover Study of Eteplirsen in Subjects With Duchenne Muscular Dystrophy (2020-03-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy Study of AVI-4658 to Induce Dystrophin Expression in Selected Duchenne Muscular Dystrophy Patients (2020-03-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Safety Study of Eteplirsen to Treat Advanced Stage Duchenne Muscular Dystrophy (2020-03-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. MS-SMART: Multiple Sclerosis-Secondary Progressive Multi-Arm Randomisation Trial (2020-03-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia (2020-03-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Identifying Biomarkers of Parkinson's Disease Using Magnetic Resonance Imaging (MRI) (2020-01-03) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Diagnosis and Treatment of Gastric Mucosa-associated Lymphoid Tissue Lymphoma]. (2019/12/25) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Modeling Resilience to Damage in Multiple Sclerosis: Plasticity Meets Connectivity. (2019/12/24) ♡
• Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing. (2019/12/23) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Lentiform Nucleus Hyperechogenicity in Parkinsonian Syndromes: A Systematic Review and Meta-Analysis with Consideration of Molecular Pathology. (2019/12/18) ♡
• Quantifying iron deposition in the cerebellar subtype of multiple system atrophy and spinocerebellar ataxia type 6 by quantitative susceptibility mapping. (2019/12/15) ♡
• Combination of midbrain-to-pontine ratio and cardiac MIBG scintigraphy to differentiate Parkinson's disease from multiple system atrophy and progressive supranuclear palsy. (2019/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Detecting neurodegenerative pathology in multiple sclerosis before irreversible brain tissue loss sets in. (2019/12/09) ♡
• Structural heterogeneity of α-synuclein fibrils amplified from patient brain extracts. (2019/12/04) ♡
• Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. (2019/12/03) ♡
• Diffusion Tensor Magnetic Resonance Imaging for Differentiating Multiple System Atrophy Cerebellar Type and Spinocerebellar Ataxia Type 3. (2019/12/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Homozygous variant, p.(Arg643Trp) in VAC14 causes striatonigral degeneration: report of a novel variant and review of VAC14-related disorders. (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Multiple system atrophy: a disorder targeting the brainstem control of survival. (2019/12/01) ♡
• Differentiating early Parkinson's disease and multiple system atrophy with parkinsonism by saccade velocity profiles. (2019/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chronic traumatic encephalopathy neuropathology might not be inexorably progressive or unique to repetitive neurotrauma. (2019/12/01) ♡
• Association of innervation-adjusted alpha-synuclein in arrector pili muscles with cardiac noradrenergic deficiency in autonomic synucleinopathies. (2019/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Conjugal cerebellar type of multiple system atrophy: Person-to-person transmission? (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Early bladder dysfunction in multiple system atrophy: who seek shall find. (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Urinary retention discriminates multiple system atrophy from Parkinson's disease. (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. TPPP/p25α Is an old and new therapeutic target in multiple system atrophy. (2019/12/01) ♡
• Case report on a 32-year-old female with elevated serum creatinine levels and primary Sjögren's syndrome-chronic interstitial nephritis. (2019/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Epigallocatechin gallate in multiple system atrophy (PROMESA). (2019/12/01) ♡

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