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Multiple system atrophy (MSA)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (38)Meta-analysis (10)Treatment guideline (2)Systematic review (14)Randomized trial (9)Phase 3 study (3)Clinical trial (478)Review article (236)Early-stage study (phase 1 or 2) (13)Case descriptions (78)Laboratory or animal research (22)Commentary or editorial (37)Retracted publication (2)Concerns have been raised (1) Studies currently recruiting participants only (34)

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Publications and studies (1558)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multiple Dose Safety and Efficacy of LKA651 in Patients With Diabetic Macular Edema (2024-06-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Investigate the Efficacy and Safety of Mexiletine in Patients With Myotonic Dystrophy Type 1 and Type 2 (2024-05-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Prader-Willi Syndrome Body Composition (2024-05-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Theory-based Home-based Multi-component Exercise Training Among Older Adults With Type 2 Diabetes Mellitus (2024-05-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Investigate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Efficacy of Risdiplam (RO7034067) in Type 2 and 3 Spinal Muscular Atrophy (SMA) Participants (2024-04-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. At-Home Research Study for Patients With Autoimmune, Inflammatory, Genetic, Hematological, Infectious, Neurological, CNS, Oncological, Respiratory, Metabolic Conditions (2024-04-18) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Open Label, Multi-Center Study, Evaluating the Effect of Adipose Tissue Processed With the SyntrFuge™ System for Facial Fat Grafting (2024-04-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. In-Home Care for Patients With PSP and Related Disorders (2024-04-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluate the Efficacy and Safety of EN001 in Patients With Duchenne Muscular Dystrophy (2024-03-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Non-invasive Spinal, Cortical, and Sensorimotor Biomarkers in Motor Neurone Disease (2024-03-20) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Assess the Efficacy, Safety, and Tolerability of Oral LPCN 1148 in Male Subjects With Cirrhosis of the Liver and Sarcopenia (2024-03-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome (2024-03-13) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. S-ADHF: Sarcopenia in Patients With ADHF (2024-03-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Progression Rate of MSA Under EGCG Supplementation as Anti-Aggregation-Approach (2024-03-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Assessment of NfL and GFAP Levels, Atrophy of the Macula GCC by OCT and Whole Brain Atrophy by MRI to Predict Evolution of Neurological Disability in MS Patients (2024-02-26) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Tirzepatide Monotherapy in Patients With Wolfram Syndrome Type 1 (2024-02-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multi-omics Analyses on Etiology and Early Detection of Stomach Cancer Precursor Lesions (2024-02-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Assess the Safety and Efficacy of Viltolarsen in Ambulant Boys With DMD (RACER53-X) (2024-02-14) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Mixed Exercise Training and Novel Multi-Nutrient Supplementation in Young Adults (2024-01-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Synapse Alterations in MSA Patients (2024-01-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Focused Ultrasound Thalamotomy for Tremor Relief in Atypical Parkinsonism (2024-01-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Efficacy and Tolerability of Ramelteon in Patients With Rapid Eye Movement (REM) Behavior Disorder and Parkinsonism (2024-01-09) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Assessing the Fertility Status of Men With Spinal Muscular Atrophy (SMA) (2024-01-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Synuclein-One Study (2024-01-03) ♡
• Exploring Vitreous Haze as a Potential Biomarker for Accelerated Glymphatic Outflow and Neurodegeneration in Multiple Sclerosis: A Cross-Sectional Study. (2023/12/30) ♡
• Detecting ferroptosis and immune infiltration profiles in multiple system atrophy using postmortem brain tissue. (2023/12/29) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Management and Treatment for Dysphagia in Neurodegenerative Disorders. (2023/12/27) ♡
• Intracerebral Distribution of CAG Repeat-Binding Small Molecule Visualized by Whole-Brain Imaging. (2023/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Planimetric and Volumetric Brainstem MRI Markers in Progressive Supranuclear Palsy, Multiple System Atrophy, and Corticobasal Syndrome. A Systematic Review and Meta-Analysis. (2023/12/19) ♡
• Association of cardiovascular disease management drugs with Lewy body dementia: a case-control study. (2023/12/18) ♡
• Early cortical atrophy is related to depression in patients with neuropathologically confirmed Parkinson's disease. (2023/12/15) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. How Certain Are You When Making the Diagnosis of Multiple System Atrophy? (2023/12/12) ♡
• Coenzyme Q10: A Biomarker in the Differential Diagnosis of Parkinsonian Syndromes. (2023/12/12) ♡
• Incidence of different pressure patterns of spinal cerebellar ataxia and analysis of imaging and genetic diagnosis. (2023/12/12) ♡
• Sentence completion in progressive supranuclear palsy following transcranial direct current stimulation. (2023/12/09) ♡
• Multi-parametric radiomics of conventional T1 weighted and susceptibility-weighted imaging for differential diagnosis of idiopathic Parkinson's disease and multiple system atrophy. (2023/12/08) ♡
• Mitofusin 2 Variant Presenting With a Phenotype of Multiple System Atrophy of Cerebellar Subtype. (2023/12/07) ♡
• α-Synuclein emulsifies TDP-43 prion-like domain-RNA liquid droplets to promote heterotypic amyloid fibrils. (2023/12/05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparison of tandospirone and escitalopram as a symptomatic treatment in Multiple System Atrophy-cerebellar ataxia: An open-label, non-controlled, 4 weeks observational study. (2023/12/01) ♡
• (13)C and (15)N resonance assignments of alpha synuclein fibrils amplified from Lewy Body Dementia tissue. (2023/12/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Transcranial magnetic stimulation neurophysiology in patients with non-Alzheimer's neurodegenerative diseases: A systematic review and meta-analysis. (2023/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Genetic and molecular biomarkers for geographic atrophy. (2023/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Increased brain cholinergic innervation in isolated REM sleep behaviour disorder from prodromal multiple system atrophy. (2023/12/01) ♡
• Corneal confocal microscopy demonstrates varying degrees of neurodegeneration in atypical parkinsonian disorders. (2023/12/01) ♡
• Estimating the prevalence and incidence of multiple system atrophy in the USA: Insights from a national claims database. (2023/12/01) ♡
• Photo-oxygenation of histidine residue inhibits α-synuclein aggregation. (2023/12/01) ♡
• REM sleep behavior disorder: update on diagnosis and management. (2023/12/01) ♡
• Secreted Metabolome of ALS-Related hSOD1(G93A) Primary Cultures of Myocytes and Implications for Myogenesis. (2023/11/30) ♡
• The Posterosuperior Tetralogy Scoring System as a Practical Tool to Predict Shoulder Function After Posterosuperior Large-to-Massive Rotator Cuff Repairs. (2023/11/28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Association of retinal vessel pathology and brain atrophy in relapsing-remitting multiple sclerosis. (2023/11/28) ♡

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