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Melanoma (metastatic)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (28)Meta-analysis (4)Treatment guideline (2)Systematic review (8)Phase 3 study (8)Randomized trial (6)Clinical Research (581)Overview article (183)Early Study (Phase 1 or 2) (58)Description of some patients (244)Laboratory or animal study (45)Commentary or editorial (17)Retracted publication (2) Studies currently seeking participants only (43)

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Publications and studies (1874)

• Clinical Outcomes of Lenvatinib-Pembrolizumab in a High-Risk, Dual ICI-Refractory Melanoma Cohort. (2026/07/27) ♡
• Thermosensitive Block Copolymer Hydrogel with Embedded Catanionic Vesicles as a Localized Doxorubicin Delivery Platform for Melanoma. (2026/07/26) ♡
• A baseline systemic inflammatory signature predicts anti-PD-1 response in advanced melanoma. (2026/07/25) ♡
• Thioredoxin interacting protein (TXNIP), a redox regulator, mediates the EPAC-RAP1 signaling dependency of primary melanoma. (2026/07/25) ♡
• The melanocytic transcriptomic state is independently associated with poor overall survival in patients with metastatic melanoma. (2026/07/24) ♡
• Autocrine CysLT(1)R-ERK/YAP signaling drives melanoma progression and reveals a targetable oncogenic GPCR axis. (2026/07/24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Global burden of skin cancers and trends from 1990 to 2021: An observational study based on secondary analysis of GBD 2021. (2026/07/24) ♡
• Mosaic RASopathy Caused by a Somatic HRAS p.Gly12Ser Variant in a Patient With Malignant Melanoma. (2026/07/23) ♡
• Hemophagocytic lymphohistiocytosis and posterior reversible encephalopathy syndrome during BRAF/MEK inhibitor therapy following immune checkpoint blockade in metastatic melanoma: a case report. (2026/07/23) ♡
• Scalp melanoma presents with greater Breslow thickness and higher metastatic burden: analysis of 105 Korean cutaneous head and neck melanoma patients. (2026/07/23) ♡
• Undifferentiated and Dedifferentiated Melanoma of the Genitourinary Tract: A Case Series Demonstrating the Potential for Diagnostic Pitfalls. (2026/07/22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Association between emotional distress and efficacy of immune checkpoint inhibitors in patients with hepatocellular carcinoma: a multicentre, prospective observational study protocol. (2026/07/22) ♡
• Deep Cavernosal Melanoma Without Clinically Evident Mucosal or Cutaneous Involvement: A Case Report. (2026/07/22) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Efficacy, safety, and characteristics of adoptive tumor-infiltrating lymphocyte therapy in solid tumours: a systematic review and meta-analysis. (2026/07/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Bacteria-related signals in brain metastases: evidence boundaries, tumor-microenvironment remodeling, and translational prospects. (2026/07/22) ♡
• Frameless stereotactic radiosurgery in the management of brain metastases: long-term oncologic and toxicity outcomes. (2026/07/21) ♡
• MOF@Pt-AuPt plasmonic scaffold enables ultrasensitive fiber-optic SPR biosensing of GPNMB toward Parkinson's disease diagnosis. (2026/07/21) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Advanced Metastatic Melanoma With C-KIT (CD117) Immunohistochemical Expression: A Case Report and Therapeutic Considerations. (2026/07/21) ♡
• primary analysis of the RANDOMIZED eortc-2139/columbus-ad trial: Adjuvant encorafenib and binimetinib versus placebo in high-risk stage II BRAF-V600E/K melanoma. (2026/07/21) ♡
• Interaction of Alkannin with CPEB4 Contributes to Its Antitumor Effects in Melanoma. (2026/07/21) ♡
• Transcriptional Reprogramming by AP-1-Bound Cis-Regulatory Elements Is Associated with Melanoma Development. (2026/07/21) ♡
• Incidence and Clinical Impact of Endocrinopathy Following First-Line Nivolumab-Plus-Relatlimab Therapy for Metastatic Melanoma. (2026/07/21) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Safety and efficacy of fecal microbiota transplantation in solid cancers resistant to immune checkpoint inhibitors: results of the MITRIC trial. (2026/07/20) ♡
• Clinically presumed primary malignant melanoma of the parotid gland with extensive cervical lymph node metastasis: a case report. (2026/07/20) ♡
• Clinical and pathologic findings of splenic tumours in four horses: a case series. (2026/07/20) ♡
• Priming of human monocytes by β-glucan and obesity-associated factors: modifications to global DNA methylation, gene expression, phenotype and function. (2026/07/20) ♡
• Neoadjuvant Immune Therapy in Patients With Melanoma: Response and Toxicity in a Non-Clinical Trial Setting. (2026/07/19) ♡
• A Self-Assembling Peptide Platform for Intratumoral Doxorubicin Delivery and Preliminary Immune-Related Modulation in B16-F10 Melanoma. (2026/07/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Decoding Post-Transcriptional Networks Governing the Melanoma Extracellular Matrix. (2026/07/18) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Current Molecular-Targeted Therapies in Melanoma and Their Mechanism of Resistance. (2026/07/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cutaneous Malignancies Metastatic to the Female Genital Tract and Pelvic Lymph Nodes: Analysis of Metastatic Patterns and Pathogenesis. (2026/07/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. SMARCB1 (INI1)-deficient malignant melanocytic neoplasm with histologically confirmed vertebral metastases in a young adult: a case report. (2026/07/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Ileal malignant melanoma presenting with severe iron-deficiency anemia and active small-bowel bleeding: primary intestinal melanoma versus metastasis - a case report and narrative review. (2026/07/15) ♡
• Efficacy and safety of immune checkpoint inhibitor rechallenge in cervical and endometrial cancer: a multi-center retrospective study (RICE study). (2026/07/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Subepithelial nevus and papilloma of the lacrimal caruncle: a case report and literature review. (2026/07/13) ♡
• Longitudinal BRAF ctDNA monitoring in melanoma reflects disease status and predicts relapse. (2026/07/13) ♡
• A Phase II Trial of Defactinib Combined with Avutometinib in Patients with Metastatic Uveal Melanoma. (2026/07/11) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case Report of Metastatic Melanoma of Unknown Primary with Massive Jejunal Involvement Mimicking Intestinal Lymphoma in a Young Adult: Diagnostic Pitfalls and Surgical Challenges. (2026/07/10) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An integrative naturopathic oncology approach in metastatic malignant melanoma: two case reports. (2026/07/10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Interleukin-1β Gene (IL1B) rs1143634 (+3954 C>T) Polymorphism and Cutaneous Melanoma Risk: An Observational Case-Control Study in Northeast Italy. (2026/07/09) ♡
• Association of BRAF Mutation Status with Histopathological Characteristics and Survival Outcomes in Stage II-III Malignant Melanoma. (2026/07/09) ♡
• Nanog(+)F10-Derived Extracellular Vesicles Suppress Melanoma Metastasis, Implicating miR-19a-3p in Macrophage-Dependent Innate Immune Regulation. (2026/07/08) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Concurrent Umbilical Endometriosis and Umbilical Hernia: A Rare Case. (2026/07/07) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acute cholecystitis revealing gastric adenocarcinoma with osseous metastasis: a case report and review of the literature. (2026/07/06) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Metastatic malignant melanoma presenting as bilateral acute mastitis in a lactating woman: a case report and literature review. (2026/07/06) ♡
• Consolidative use of radiotherapy to block oligoprogression in patients with metastatic melanoma on Systemic Therapy (CURB-Melanoma) - a single arm, phase 2 clinical trial. (2026/07/06) ♡
• Therapy-Associated Vitiligo: Hypopigmentation Secondary to Programmed Cell Death Protein 1 Inhibitors, Interferon Alfa-2b, Cytotoxic T-Lymphocyte-Associated Protein 4 Inhibitors, and B-Raf/Mitogen-Activated Protein Kinase Kinase Inhibitors. (2026/07/04) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Neoadjuvant Cemiplimab in Cutaneous Squamous Cell Carcinoma: Complete Primary Tumor Response with Regional Nodal Metastases Case Report. (2026/07/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pediatric Uveal Melanoma Masquerading as Vitreous Hemorrhage: A Case Report. (2026/07/01) ♡
• Immune-Related Adverse Events and Therapeutic Outcomes After Stopping Immune Checkpoint Inhibitors due to Toxicity Among Patients With Metastatic Melanoma (University Hospitals Sussex). (2026/07/01) ♡

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