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Melanoma (metastatic)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchOnly the strongest evidence (27)Meta-analysis (4)Treatment guideline (2)Systematic review (8)Phase 3 study (7)Randomized trial (6)Clinical trial (585)Review article (181)Early study (phase 1 or 2) (54)Case report (241)Laboratory or animal study (45)Commentary or editorial (17)Retracted publication (2) Studies currently recruiting participants only (39)

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Publications and studies (1860)

• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Uveal Melanoma: Changing Paradigms of Treatment. (2026/06/01) ♡
• Glycoprotein non-metastatic melanoma protein B promotes pyroptosis of macrophages induced by homocysteine associated with the upregulation of the NOX-2/ NF-κB signaling pathway. (2026/06/01) ♡
• Fractionated stereotactic re-irradiation after plaque radiotherapy (brachytherapy) failure in uveal melanoma. (2026/06/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Diffuse Amelanotic Choroidal Melanoma Mimicking Mushrooming Melanocytic Melanoma and Choroidal Metastasis in a Patient with Dual Primary Malignancies: A Case Report. (2026/06/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Recent advances in the molecular genetic mechanisms and immune microenvironment of uveal melanoma. (2026/06/01) ♡
• Frozen melanoma tissues yield extracellular vesicles with preserved diagnostic and immunogenic properties. (2026/05/21) ♡
• Predicting of survival in metastatic melanoma patients under anti-PD-1 monotherapy using genomic mutation and copy number variation. (2026/05/18) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Investigation of oral bromelain supplementation on the healing of skin flap reconstruction after Mohs micrographic surgery (MMS) for non-melanoma skin cancers (NMSCs). (2026/05/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The immune landscape of melanoma microenvironmental crosstalk. (2026/05/11) ♡
• Local Flaps in Nasal Reconstruction Following Non-Melanocytic Skin Cancer Ablation. (2026/05/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Delayed diagnosis of metastatic melanoma reoccurrence: Case report. (2026/05/01) ♡
• Advanced metastatic melanoma in a young adult: A consequence of delayed diagnosis due to social barriers? (2026/04/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Triphasic Adrenocorticotropic Hormone Dynamics During Immune Checkpoint Inhibitor Therapy in a Patient With Malignant Melanoma. (2026/04/18) ♡
• Contemporary Tumor Histology Grouping for Survival Prediction of Patients With Metastatic Long-bone Disease Undergoing Surgery. (2026/04/15) ♡
• Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma. (2026/04/01) ♡
• RYK is a GPNMB receptor that drives MASH. (2026/04/01) ♡
• Machine learning-based association analysis of triglyceride-glucose index with melanoma prevalence and all-cause mortality: insights from cross-sectional NHANES 1999-2018 data and an external hospital-based dataset. (2026/03/18) ♡
• Acyl-CoA synthetase long-chain family member 4-A novel prognostic marker in cutaneous melanoma. (2026/03/16) ♡
• Combining information on degradomics and gene expression data in prospecting metastatic melanoma proteolytic signatures. (2026/03/15) ♡
• Disitamab vedotin with or without PD-1 inhibitors in pretreated patients with locally advanced or metastatic urothelial carcinoma: Identifying patients who derive additional benefit from immune combination therapy. (2026/03/01) ♡
• Evaluation of Optical Coherence Tomography for Metastatic Lymph Node Identification in Canine Oral Malignant Melanoma. (2026/03/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Tumor immune-vascular crosstalk: synergy and translation of immune checkpoint inhibitors and anti-angiogenic agents in melanoma. (2026/02/12) ♡
• Nanoengineering of cyclic dinucleotide‑manganese complexes using biodegradable mesoporous silica nanoparticles for cancer metallo-immunotherapy. (2026/02/10) ♡
• Discontinuation of BRAF/MEK inhibitor therapy after long-lasting response: Clinical outcomes in advanced melanoma. (2026/02/05) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. [Tisotumab Vedotin - Metastatic or recurrent cervical cancer as second-line therapy]. (2026/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Interdigitating Dendritic Cell Sarcoma Arising on the Skin: An Exceedingly Rare Tumor With a Poor Prognosis. (2026/02/01) ♡
• Incensole enhances anti-tumor immunity and inhibits melanoma progression by modulating macrophage polarization and suppressing metastasis. (2026/02/01) ♡
• Prognostic Value of Systemic Inflammatory Markers in Locally Advanced or Metastatic Melanoma: A Real-World Analysis. (2026/01/28) ♡
• Intratumoral delivery of probiotic Ligilactobacillus salivarius H22A013 modulates the melanoma microenvironment and enhances trametinib efficacy. (2026/01/27) ♡
• A lung specific escape of intravascular metastatic breast cancer cells from cytotoxic T cell killing. (2026/01/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Melanoma vaccines: current R&D landscape, translational hurdles, and future outlook-a perspective drawn from 442 clinical trials. (2026/01/19) ♡
• Targeting PDPN enhances antitumor T-cell activity by disrupting β-catenin-mediated PD-L1 expression in melanoma. (2026/01/07) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hematologic immune-related adverse events in skin cancer patients treated with immune checkpoint inhibitors: a case series. (2026/01/06) ♡
• SPACA6-hosted miR-99b~125a~let-7e cluster shapes melanoma resistance by modulating mTOR-mediated immunosuppression. (2026/01/02) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Unraveling the mystery of gastric nodular mass: A rare case highlighting the diagnostic challenge of metastatic amelanotic melanoma. (2026/01/01) ♡
• Analysis of overall survival in patients with second primary malignancies following with the first diagnosis of nonmetastatic prostate cancer: A study utilizing the Surveillance, Epidemiology, and End Results database. (2026/01/01) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of MGC026 in Participants With Advanced Solid Tumors (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Ibrutinib in Treating Patients With Refractory Metastatic Cutaneous Melanoma (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Testing the Addition of Navitoclax to the Combination of Dabrafenib and Trametinib in People Who Have BRAF Mutant Melanoma (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors (2026-08-10) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of mRNA-4106 or mRNA-4200 Administered Alone or in Combination With Anti-Cancer Agents in Participants With Solid Tumors (2026-08-10) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Safety and Preliminary Efficacy of MBS8(1V270) in Cancer Patients With Advanced Solid Tumours (2026-08-10) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Tunlametinib in Combination With Pucotenlimab and Hydroxychloroquine in NRAS Mutant Melanoma (2026-08-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Harvesting Cells for Experimental Cancer Treatments (2026-08-07) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study (2026-08-07) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Trametinib With or Without GSK2141795 in Treating Patients With Metastatic Uveal Melanoma (2026-08-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors (2026-08-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Testing Treatment With Encorafenib and Binimetinib Before Surgery for Melanoma With Lymph Node Involvement (2026-08-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. High Dose IL-2 in Combination With Anti-PD-1 (2026-08-06) ♡

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