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Alpha-1 antitrypsin deficiency

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest Level of Evidence Only (35)Meta-analysis (8)Treatment guideline (5)Phase 3 study (8)Randomized trial (8)Systematic review (6)Clinical Trial (169)Review article (176)Early study (phase 1 or 2) (18)Case report (114)Laboratory or animal study (26)Commentary or editorial (90)Retracted publication (1) Only studies currently recruiting participants (28)

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Publications and studies (1172)

• Impact of Coronavirus Disease 2019 and Vaccination Attitudes on Alpha-1 Antitrypsin Deficiency. (2023/10/26) ♡
• Chymotrypsin-like Elastase-1 Mediates Progressive Emphysema in Alpha-1 Antitrypsin Deficiency. (2023/10/26) ♡
• Augmentation Therapy for Alpha-1 Antitrypsin Deficiency: Patient Experiences With Self-Infusion, Home Providers, and Clinics. (2023/10/26) ♡
• Impact of the COVID-19 pandemic on well-being and quality of life of patients with alpha-1-antitrypsin deficiency. (2023/10/25) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Glioblastoma Multiforme in a Patient With Alpha-1-Antitrypsin Deficiency. (2023/10/20) ♡
• Cardiovascular Risk Associated with Alpha-1 Antitrypsin Deficiency (AATD) Genotypes: A Meta-Analysis with Meta-Regressions. (2023/10/12) ♡
• Type 1 diabetes contributes to combined pulmonary fibrosis and emphysema in male alpha 1 antitrypsin deficient mice. (2023/10/11) ♡
• Testing Patterns and Disparities for Alpha-1 Antitrypsin Deficiency. (2023/10/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. CLINICAL, LABORATORIAL AND EVOLUTIONARY ASPECTS OF PEDIATRIC PATIENTS WITH LIVER DISEASE DUE TO ALPHA 1-ANTITRYPSIN DEFICIENCY. (2023/10/01) ♡
• α(1)-Antitrypsin deficiency associated with increased risk of heart failure. (2023/09/25) ♡
• Development of a risk score to increase detection of severe alpha-1 antitrypsin deficiency. (2023/09/18) ♡
• Increased expression or activation of TRPML1 reduces hepatic storage of toxic Z alpha-1 antitrypsin. (2023/09/06) ♡
• Genotypic Frequencies of Mutations Associated with Alpha-1 Antitrypsin Deficiency in Unrelated Bone Marrow Donors from the Murcia Region Donor Registry in the Southeast of Spain. (2023/09/02) ♡
• Modulation of the structural and functional properties of α1-antitrypsin by interaction with flavonoid luteolin. (2023/09/01) ♡
• A novel endoplasmic reticulum adaptation is critical for the long-lived Caenorhabditis elegans rpn-10 proteasomal mutant. (2023/09/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha1-antitrypsin deficiency: An updated review. (2023/09/01) ♡
• Population genetic testing and SERPINA1 sequencing identifies unidentified alpha-1 antitrypsin deficiency alleles and gene-environment interaction with hepatitis C infection. (2023/08/31) ♡
• Utility of the Serum Protein Electrophoresis in the Opportunistic Screening for the Deficiency of Alpha-1 Antitrypsin. (2023/08/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Protein Phosphatase 2A as a Therapeutic Target in Pulmonary Diseases. (2023/08/26) ♡
• A Novel Provider Education Module to Enhance Detection of Alpha-1 Antitrypsin Deficiency. (2023/08/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Bilateral giant emphysematous bullae complicate severe bronchial asthma in a young patient: case report. (2023/08/14) ♡
• The prevalence of bronchiectasis in patients with alpha-1 antitrypsin deficiency: initial report of EARCO. (2023/08/12) ♡
• [Detection of cases of Alpha-1 Antitrypsin Deficiency, Should We Restrict or Expand?]. (2023/08/07) ♡
• Quantitative Lipid Profiling Reveals Major Differences between Liver Organoids with Normal Pi*M and Deficient Pi*Z Variants of Alpha-1-antitrypsin. (2023/08/05) ♡
• Recommendations for the Implementation of the Self-Administration of Alpha-1 Antitrypsin. (2023/08/04) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Beneficial effects of alpha-1 antitrypsin therapy in a mouse model of colitis-associated colon cancer. (2023/08/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Improving Detection of Alpha-1 Antitrypsin Deficiency: Role of the Allergist. (2023/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies. (2023/08/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pediatric and Adult Liver Disease in Alpha-1 Antitrypsin Deficiency. (2023/08/01) ♡
• Cryptogenic chronic hepatitis: looking for an ideal diagnostic algorithm. (2023/08/01) ♡
• Initial alpha-1 antitrypsin screening in Turkish patients with chronic obstructive pulmonary disease. (2023/08/01) ♡
• Impact of Bronchiectasis on COPD Severity and Alpha-1 Antitrypsin Deficiency as a Risk Factor in Individuals with a Heavy Smoking History. (2023/07/26) ♡
• Augmentation Therapy Modulates Systemic Inflammation in Individuals with Alpha-1 Antitrypsin Deficiency and Chronic Obstructive Pulmonary Disease. (2023/07/26) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Diagnosis and augmentation therapy for alpha-1 antitrypsin deficiency: current knowledge and future potential. (2023/07/20) ♡
• Predicting Lung Function Using Biomarkers in Alpha-1 Antitrypsin Deficiency. (2023/07/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. NAFLD and AATD Are Two Diseases with Unbalanced Lipid Metabolism: Similarities and Differences. (2023/07/12) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Meta-analysis: Prevalence of significant or advanced fibrosis in adults with alpha-1-antitrypsin deficiency. (2023/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Practical dietary advices for subjects with alpha-1 antitrypsin deficiency. (2023/07/01) ♡
• Current Perspectives of Pharmacotherapies for COPD. (2023/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. RNAi therapeutics for diseases involving protein aggregation: fazirsiran for alpha-1 antitrypsin deficiency-associated liver disease. (2023/07/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-1-antitrypsin antagonizes COVID-19: a review of the epidemiology, molecular mechanisms, and clinical evidence. (2023/06/28) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Preservation solution Custodiol containing human alpha-1-antitrypsin improves graft recovery after prolonged cold ischemic storage in a rat model of heart transplantation. (2023/06/22) ♡
• Increased Prevalence of Alpha-1-Antitrypsin Deficiency in Patients with Biliary Tract Cancer and Its Associated Clinicopathological Features. (2023/06/19) ♡
• Physical Activity, Exercise Capacity and Sedentary Behavior in People with Alpha-1 Antitrypsin Deficiency: A Scoping Review. (2023/06/16) ♡
• Estimating the Prevalence of AATD Patients in the UK to Identify Underdiagnosis and Determine the Eligibility for Potential Augmentation Therapy. (2023/06/13) ♡
• Lung microhaemorrhage drives oxidative/inflammatory damage in α(1)-antitrypsin deficiency. (2023/06/12) ♡
• [Results of the Implementation of a Case-Finding Program for Alpha-1 Antitrypsin Deficiency in COPD Patients]. (2023/06/09) ♡
• Distribution of alpha1 antitrypsin rare alleles in six countries: Results from the Progenika diagnostic network. (2023/06/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Alpha-1 Antitrypsin Deficiency. (2023/06/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Important steps towards a big change for lung health: a joint approach by the European Respiratory Society, the European Society of Radiology and their partners to facilitate implementation of the European Union's new recommendations on lung cancer screening. (2023/05/09) ♡

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