← All diseases Lungs and airways

Alpha-1 antitrypsin deficiency

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest Level of Evidence Only (35)Meta-analysis (8)Treatment guideline (5)Phase 3 study (8)Randomized trial (8)Systematic review (6)Clinical Trial (169)Review article (176)Early study (phase 1 or 2) (18)Case report (114)Laboratory or animal study (27)Commentary or editorial (90)Retracted publication (1) Only studies currently recruiting participants (28)

Filter

Publications and studies (1173)

• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction (2025-09-10) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study to Evaluate Efficacy and Safety of VX-864 in Participants With the PiZZ Genotype (2025-09-08) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase III, Efficacy and Safety of "Kamada-AAT for Inhalation" (2025-09-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Baby Detect : Genomic Newborn Screening (2025-08-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study of SAR447537 (INBRX-101) Compared to Plasma-derived A1PI Therapy in Adults With AATD Emphysema (2025-08-11) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of KB408 for the Treatment of Alpha-1 Antitrypsin Deficiency (2025-07-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Epigenetic Regulation of Immunity in Alpha-1 Anti-trypsin Deficiency (2025-06-06) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Respreeza® Self-administration and Learning Program (AmAREtTI Study) (2025-05-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Alpha-1-Antitrypsin-Deficiency in COVID-19 (2025-05-25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Preparation of IPSC for Cell Gene Editing for the Treatment of AATD (2025-03-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NTLA-3001 in Adults with Alpha-1 Antitrypsin Deficiency-Associated Lung Disease (2025-01-17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Pulmonary artery aneurysm as a rare manifestation of Alpha-1 antitrypsin deficiency. (2024/12/27) ♡
• Lung transplant outcomes for recipients with alpha-1 antitrypsin deficiency, by use of alpha-1 antitrypsin augmentation therapy. (2024/12/24) ♡
• Optimising bronchoalveolar lavage: lessons from alpha-1 antitrypsin deficiency. (2024/12/23) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Quantitative BAL: a suitable method for the assessment of epithelial lining fluid in alpha-1 antitrypsin deficiency? (2024/12/23) ♡
• Infections, autoimmunity and immunodeficiencies are the leading etiologies of non-cystic fibrosis bronchiectasis in adults from the southwest of Colombia. (2024/12/23) ♡
• Clinical implications of the SERPINA1 variant, M(Palermo), and alpha-1 antitrypsin deficiency in Türkiye. (2024/12/18) ♡
• Can Quality of Life Tests Be Useful in Patients Affected by Alpha-1 Antitrypsin Deficiency? (2024/12/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Alpha-1 antitrypsin deficiency and augmentation therapy in pregnancy: two case reports. (2024/12/16) ♡
• COVID-19 in Individuals with Severe Alpha 1-Antitrypsin Deficiency. (2024/12/09) ♡
• Recommendations for the diagnosis and treatment of alpha-1 antitrypsin deficiency. (2024/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Drug-induced liver injury related to gene therapy: A new challenge to be managed. (2024/12/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fibrosis, biomarkers and liver biopsy in AAT deficiency and relation to liver Z protein polymer accumulation. (2024/12/01) ♡
• Machine-Learning Model Identifies Patients With Alpha-1 Antitrypsin Deficiency Using Claims Records. (2024/12/01) ♡
• Alpha-1 antitrypsin deficiency associated with increased risks of skin cancer, leukemia, and hepatic cancer: A nationwide cohort study. (2024/12/01) ♡
• Alpha-1 antitrypsin inhibits pertussis toxin. (2024/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Alpha-1 Antitrypsin Deficiency: Navigating Challenges Through Collaborative Innovation. (2024/12/01) ♡
• Alpha-1 Antitrypsin Deficiency in a Young Never Smoker With Novel Pi*Null Homozygous Mutation: a Case Report. (2024/11/22) ♡
• A Multimodal Intervention to Improve Guideline-Based Screening for Alpha-1 Antitrypsin Deficiency in a Community Health Setting. (2024/11/22) ♡
• Higher healthcare cost and utilization before and after diagnosis of AATD in the United States. (2024/11/16) ♡
• Plasma collagen neoepitopes are associated with multiorgan disease in the ACCESS and GRADS sarcoidosis cohorts. (2024/11/14) ♡
• The association between alpha-1 antitrypsin and B-type natriuretic peptide blood levels in healthy African Americans. (2024/11/07) ♡
• European Alpha-1 Research Collaboration (EARCO) in Portugal: The Future Is Happening. (2024/11/04) ♡
• Understanding the Added Value of High-Resolution CT Beyond Chest X-Ray in Determining Extent of Physiologic Impairment. (2024/11/01) ♡
• Haplotype-Aware Detection of SERPINA1 Variants by Nanopore Sequencing. (2024/11/01) ♡
• Physical and mental health trajectories: A longitudinal SF-36 analysis in Alpha-1 antitrypsin deficiency-associated COPD. (2024/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Lung transplantation for alpha-1-antitrypsin deficiency and Behçet's disease: A case report. (2024/11/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A novel alpha-1 antitrypsin gene variant in a patient with Kartagener's syndrome: a case report. (2024/10/31) ♡
• Hospital Admission Trends in Alpha-1-Antitrypsin Deficiency: A Sex-Based Analysis from the Spanish National Discharge Database, 2016-2022. (2024/10/31) ♡
• Liver Characterization of a Cohort of Alpha-1 Antitrypsin Deficiency Patients with and without Lung Disease. (2024/10/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Psychiatric Disorders in Patients with Chronic Obstructive Pulmonary Disease: Clinical Significance and Treatment Strategies. (2024/10/26) ♡
• High BMI and COPD Outcomes in Alpha-1 Antitrypsin Deficiency. (2024/10/19) ♡
• Alpha 1 antitrypsin augmentation for alpha 1 antitrypsin deficiency associated lung disease. (2024/10/16) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Fazirsiran for Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Phase 2 Placebo Controlled Trial (SEQUOIA). (2024/10/01) ♡
• Association of circulating Z-polymer with adverse clinical outcomes and liver fibrosis in adults with alpha-1 antitrypsin deficiency. (2024/10/01) ♡
• Alcohol consumption and liver phenotype of individuals with alpha-1 antitrypsin deficiency. (2024/10/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. A Further Step Toward Possible Treatment of Alpha-1 Antitrypsin Deficiency-Associated Liver Disease. (2024/10/01) ♡
• Bronchiectasis Occurs Independently of Chronic Obstructive Pulmonary Disease in Alpha-1 Antitrypsin Deficiency. (2024/09/27) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. [Reappraisal on the clinical diagnosis and treatment of hereditary liver diseases]. (2024/09/20) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Berberine potentiates liver inflammation and fibrosis in the PI*Z hAAT transgenic murine model. (2024/09/19) ♡

↑ Back to top

codex.care does not provide medical advice. Always discuss symptoms, medication, and treatment choices with your own healthcare provider.