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Systemic sclerosis (scleroderma)

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (63)Meta-analysis (20)Treatment guideline (3)Systematic review (23)Randomized trial (11)Phase 3 study (6)Clinical trial (613)Review article (412)Early study (phase 1 or 2) (29)Case report (177)Laboratory or animal study (26)Commentary or editorial (42)Retracted publication (2) Studies currently recruiting participants only (39)

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Publications (1494)

• Meeting Report on "10th Anniversary Symposium on Inflammatory Skin Disease". (2024/12/24) ♡
• ADAM Metallopeptidase domain 19 promotes skin fibrosis in systemic sclerosis via neuregulin-1. (2024/12/23) ♡
• Evaluating the role of active TGF-β1 as inflammatory biomarker in Kashmiri (North-Indian) patients with systemic sclerosis: a case-control study. (2024/12/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rationale for phosphodiesterase-4 inhibition as a treatment strategy for interstitial lung diseases associated with rheumatic diseases. (2024/12/23) ♡
• The Efficacy and Tolerability of Prostaglandin Analogues in Treating Systemic Sclerosis-Associated Raynaud Phenomenon: A Systematic Review and Meta-Analysis. (2024/12/23) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Endostatin as a biomarker of systemic sclerosis: insights from a systematic review and meta-analysis. (2024/12/23) ♡
• Macrophages Contribute to Cardiac Fibrosis and Diastolic Dysfunction in Systemic Sclerosis. (2024/12/23) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Atypical Presentation of Optic Neuritis in Multiple Sclerosis. (2024/12/21) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. The Therapeutic Potential of Oral Everolimus for Facial Angiofibromas in Pediatric Tuberous Sclerosis Complex: A Case-Based Analysis of Efficacy. (2024/12/20) ♡
• A Scleroderma and Raynaud's UK (SRUK) national survey to explore rheumatologists' awareness, approaches to diagnosis and management and training needs within systemic sclerosis. (2024/12/20) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Clinical Characteristics and Management of Oral Candidiasis Associated with Calcinosis, Raynaud's Phenomenon, Esophageal Dysmotility, Sclerodactyly, and Telangiectasia Syndrome. (2024/12/20) ♡
• Quantitative (18)F-FDG PET-CT can assess presence and extent of interstitial lung disease in early severe diffuse cutaneous systemic sclerosis. (2024/12/19) ♡
• Non-Invasive Cardiac and Vascular Monitoring in Systemic Sclerosis: Impact of Therapy on Subclinical Dysfunction. (2024/12/19) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. [Expression and significance of ferroptosis marker 4-HNE in in vitro model of systemic sclerosis]. (2024/12/18) ♡
• [COVID-19 vaccines efficacy and infection features in patients with systemic sclerosis: A single-center cohort study]. (2024/12/18) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Dorsoventral photobiomodulation therapy safely reduces inflammation and sensorimotor deficits in a mouse model of multiple sclerosis. (2024/12/18) ♡
• Unveiling the shared genes between systemic sclerosis and lung cancer. (2024/12/18) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. CD19 CAR-T cell therapy: a new dawn for autoimmune rheumatic diseases? (2024/12/17) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Bifidobacterium longum RAPO Attenuates Dermal and Pulmonary Fibrosis in a Mouse Model of Systemic Sclerosis through Macrophage Modulation and Growth of Short-Chain Fatty Acid Producers. (2024/12/17) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. C3 deficiency promotes pulmonary inflammation in AT1R-induced mouse model for systemic sclerosis. (2024/12/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Cellular therapies in rheumatic and musculoskeletal diseases. (2024/12/16) ♡
• Neuro-Behçet's Disease Masquerading as Multiple Sclerosis in a Young Male. (2024/12/15) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Case report: Systemic sclerosis during neoadjuvant therapy for breast cancer in a 59-year-old woman. (2024/12/13) ♡
• Tuberous sclerosis: a survey in the canton of Vaud, Switzerland. (2024/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The advent of chimeric antigen receptor T Cell therapy in recalibrating immune balance for rheumatic autoimmune disease treatment. (2024/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Exploring New and Potential Indications for Botulinum Toxin Treatment: An Updated Literature Review. (2024/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Effects of Probiotics on Neurodegenerative Disease-Related Symptoms and Systemic Inflammation: A Systematic Review. (2024/12/10) ♡
• Severe Spinal Stenosis Secondary to a CREST Syndrome Related Calcific Deposit: A Case Report. (2024/12/10) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Vitamin, antioxidant and micronutrient supplementation and the risk of developing incident autoimmune diseases: a systematic review and meta-analysis. (2024/12/09) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Neuromyelitis Optica Spectrum Disorder With Unilateral Retrobulbar Neuritis: A Case Report. (2024/12/09) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Drug reaction with eosinophilia and systemic symptoms with toxic epidermal necrolysis like rash in systemic sclerosis and overlapping sjogren's syndrome: A double trouble triggered by a herbal medicine. (2024/12/07) ♡
• Psychological features of systemic sclerosis: results from an observational study. (2024/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Impact of Mast Cell Activation on Neurodegeneration: A Potential Role for Gut-Brain Axis and Helicobacter pylori Infection. (2024/12/06) ♡
• Postural stability and fall risk in systemic sclerosis patients. (2024/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Macrophages in inflammatory skin diseases and skin tumors. (2024/12/05) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. BMP-4 and fetuin A in systemic sclerosis patients with or without calcinosis. (2024/12/03) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Digital Ulcers and Microvascular Abnormalities Presenting As the Initial Manifestations of Pre-scleroderma. (2024/12/03) ♡
• Genetic Association of Juvenile Idiopathic Arthritis With Adult Rheumatic Disease. (2024/12/02) ♡
• Patients with systemic sclerosis frequently use phytopharmaceuticals: a cross-sectional survey. (2024/12/01) ♡
• Prognostic Value of Systemic Inflammation, Nutritional Status and Sarcopenia in Patients With Amyotrophic Lateral Sclerosis. (2024/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Uncommon but Significant: Onset, Characteristics and Management of Vasculitis and Connective Tissue Diseases Induced by Immunomodulators during Cancer Treatment. (2024/12/01) ♡
• Regulation of involucrin and signalling pathway in scleroderma epidermal keratinocytes. (2024/12/01) ♡
• ESOPHAGEAL DIAMETER ON HIGH-RESOLUTION COMPUTED TOMOGRAPHY - A POTENTIAL USEFUL MARKER FOR INTERSTITIAL LUNG DISEASE SEVERITY IN PATIENTS WITH SYSTEMIC SCLEROSIS. (2024/12/01) ♡
• Enhanced sclerotherapy for vascular malformations: A dual-mechanism approach using in-situ forming PATDs gel. (2024/11/30) ♡
• Inflammatory and Nutritional Markers as Indicators for Diagnosing and Assessing Disease Activity in MS and NMOSD. (2024/11/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Advanced Neuroimaging and Clinical Findings in a Case of Linear Scleroderma En Coup De Sabre Presenting With Seizures. (2024/11/28) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Critical Analysis of Cytoplasmic Progression of Inflammatory Signaling Suggests Potential Pharmacologic Targets for Wound Healing and Fibrotic Disorders. (2024/11/28) ♡
• Causal association between non-thyroidal autoimmune diseases and Graves' ophthalmopathy: A mendelian randomization study. (2024/11/22) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Portal Hypertension: An Uncommon Cause of Chylothorax and an Atypical Association With Systemic Sclerosis. (2024/11/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Beyond the Stroke: A Case Report of Multiple Sclerosis. (2024/11/18) ♡

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