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Systemic sclerosis (scleroderma)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (63)Meta-analysis (20)Treatment guideline (3)Systematic review (23)Randomized trial (11)Phase 3 study (6)Clinical trial (613)Review article (416)Early study (phase 1 or 2) (29)Case report (178)Laboratory or animal study (26)Commentary or editorial (42)Retracted publication (2) Studies currently recruiting participants only (39)

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Publications (1500)

• Physiologically based pharmacokinetic modeling of altered tizanidine systemic exposure by CYP1A2 modulation: Impact of drug-drug interactions and cigarette consumption. (2021/04/01) ♡
• Evaluating skeletal muscle mass with ultrasound in patients with systemic sclerosis. (2021/04/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Targeting citrullination in autoimmunity: insights learned from preclinical mouse models. (2021/04/01) ♡
• The prevalence and significance of anti-PM/Scl antibodies in systemic sclerosis. (2021/03/18) ♡
• The PREdictor of MAlnutrition in Systemic Sclerosis (PREMASS) Score: A Combined Index to Predict 12 Months Onset of Malnutrition in Systemic Sclerosis. (2021/03/17) ♡
• Deep Learning Classification of Systemic Sclerosis Skin Using the MobileNetV2 Model. (2021/03/17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A pilot clinical trial with losartan in Myhre syndrome. (2021/03/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Immunomodulating role of the JAKs inhibitor tofacitinib in a mouse model of bleomycin-induced scleroderma. (2021/03/01) ♡
• Assessing Malnutrition in Systemic Sclerosis With Global Leadership Initiative on Malnutrition and European Society of Clinical Nutrition and Metabolism Criteria. (2021/03/01) ♡
• Cytokines, 25-OH vit D and disease activity in patients with juvenile-onset systemic lupus erythematosus. (2021/03/01) ♡
• Histological patterns of renal diseases in children: A 12-year experience from a single Tertiary Care Center in North-East India. (2021/03/01) ♡
• [Evaluation of nutritional status in patients with systemic sclerosis]. (2021/02/24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Association of Systemic Sclerosis and Periodontitis with Vitamin D Levels. (2021/02/23) ♡
• TSC1 Suppresses Macrophage Necroptosis for the Control of Infection by Fungal Pathogen Candida albicans. (2021/02/17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Serum amyloid A level correlates with T2 lesion volume and cortical volume in patients with multiple sclerosis. (2021/02/15) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Delayed onset hypophysitis after therapy with daclizumab for multiple sclerosis - A report of two cases. (2021/02/15) ♡
• Identification of Autoimmunity to Peptides of Collagen V α1 Chain as Newly Biomarkers of Early Stage of Systemic Sclerosis. (2021/02/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus. (2021/02/03) ♡
• Gastrointestinal involvement in systemic sclerosis: Effects on morbidity and mortality and new therapeutic approaches. (2021/02/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Systemic sclerosis overlap and non-overlap syndromes share clinical characteristics but differ in prognosis and treatments. (2021/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Thymoquinone in autoimmune diseases: Therapeutic potential and molecular mechanisms. (2021/02/01) ♡
• Meta-analysisiAll studies on one question combined and calculated together. This is the strongest form of research that exists: a single loose study can be coincidence, dozens together much less so. The label says something about the design, not about the outcome — which can also be that something does NOT work. Quantitative evaluation of callosal abnormalities in relapsing-remitting multiple sclerosis using diffusion tensor imaging: A systemic review and meta-analysis. (2021/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Use of nintedanib in interstitial lung disease other than idiopathic pulmonary fibrosis: much caution is warranted. (2021/02/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. The JANUS of chronic inflammatory and autoimmune diseases onset during COVID-19 - A systematic review of the literature. (2021/02/01) ♡
• Use of vonoprazan for management of systemic sclerosis-related gastroesophageal reflux disease. (2021/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The rationale for targeting the JAK/STAT pathway in scleroderma-associated interstitial lung disease. (2021/02/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Are troponin and B-type natriuretic peptides useful biomarkers for the diagnosis of systemic sclerosis heart involvement? A systematic literature review. (2021/02/01) ♡
• Overall mortality. (2021/02/01) ♡
• Mortality and morbidity in scleroderma renal crisis: A systematic literature review. (2021/02/01) ♡
• Mycophenolic acid drug monitoring in patients with systemic sclerosis associated with diffuse skin and/or pulmonary involvement: A monocentric and retrospective French study. (2021/02/01) ♡
• Requirements for systemic sclerosis expert centres in the Netherlands: A Delphi consensus study. (2021/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. COVID-19 and systemic sclerosis: Rising to the challenge of a pandemic. (2021/02/01) ♡
• Impact of COVID-19 on outpatient therapy with iloprost for systemic sclerosis digital ulcers. (2021/02/01) ♡
• Comparing paediatric- and adult-onset linear morphoea in a large tertiary-referral scleroderma centre. (2021/02/01) ♡
• Hematopoietic stem cell transplantation in systemic sclerosis: Yes!! BUT. . (2021/02/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The multifaceted problem of pulmonary arterial hypertension in systemic sclerosis. (2021/02/01) ♡
• Update on Morbidity and Mortality in Systemic Sclerosis-Related Interstitial Lung Disease. (2021/02/01) ♡
• Advances at the Interface of Cancer and Systemic Sclerosis. (2021/02/01) ♡
• Considerations for a combined index for limited cutaneous systemic sclerosis to support drug development and improve outcomes. (2021/02/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Thyroid Warthin-Like Cancer Concurrent With Multiple Sclerosis: A Case Report. (2021/02/01) ♡
• Mast Cell Activation in the Systemic Sclerosis Esophagus. (2021/02/01) ♡
• Optic Perineuritis and Its Association With Autoimmune Diseases. (2021/01/29) ♡
• Finger sweating levels evaluated by video capillaroscopy system are increased in patients with systemic sclerosis compared to pre-clinical stage patients. (2021/01/23) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Editorial: Interstitial Lung Disease in the Context of Systemic Disease: Pathophysiology, Treatment and Outcomes. (2021/01/20) ♡
• From a Designer Drug to the Discovery of Selective Cannabinoid Type 2 Receptor Agonists with Favorable Pharmacokinetic Profiles for the Treatment of Systemic Sclerosis. (2021/01/14) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Epstein-Barr Virus and Systemic Autoimmune Diseases. (2021/01/07) ♡
• Adipose tissue is a critical regulator of osteoarthritis. (2021/01/05) ♡
• Epidemiological profile of systemic sclerosis in the southeast region of Romania. (2021/01/01) ♡
• Etiological factors of systemic sclerosis in the southeast region of Romania. (2021/01/01) ♡
• Development of a Musculoskeletal Ultrasound Protocol to Examine Upper Extremity Rehabilitation Outcomes in Systemic Sclerosis. (2021/01/01) ♡

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