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Sjögren's syndrome

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest level of evidence only (81)Meta-analysis (21)Treatment guideline (1)Systematic review (27)Phase 3 study (19)Randomized controlled trial (13)Clinical trials (79)Review article (235)Early study (phase 1 or 2) (33)Case description (220)Laboratory or animal studies (20)Commentary or editorial (36)Retracted publication (3) Studies Currently Seeking Participants Only (38)

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Publications and studies (1361)

• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Safety of Tofacitinib, an Oral Janus Kinase Inhibitor, in Primary Sjogren Disease (2026-07-21) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Efficacy and Safety of IMVT-1402 in Adult Participants With Primary Sjogren's Disease With Moderate to Severe Systemic Disease Activity (2026-07-10) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Two-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjogren's Syndrome (2026-07-07) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Safety and Efficacy of Topical Infliximab in Autoimmune Dry Eye Disease (2026-06-26) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Three-arm Study to Assess Efficacy and Safety of Ianalumab (VAY736) in Patients With Active Sjögren's Syndrome (2026-06-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comprehensive Evaluation of Clinical and Biopsychosocial Characteristics in Primary Sjögren's Disease (2026-06-09) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. ADX-629 Therapy for Sjogren-Larsson Syndrome (2026-05-05) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. A Study to Evaluate the Efficacy and Safety of Deucravacitinib in Adults With Active Sjögren's Syndrome (2026-04-01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Pregnancy and Medically Assisted Conception in Rare Diseases (2026-03-27) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Fatigue in Sjögren's Syndrome: 3 Therapeutic Strategies (2026-03-27) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Trial to Evaluate the Efficacy and Safety of Sibeprenlimab Administered Subcutaneously in Participants With Sjögren's (2026-03-18) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Umbilical Cord Blood CD19-BCMA CART Cell Therapy for SLE-LN, SSc, andpSS PAH. (2026-03-03) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. TREATMENT OF VAGINAL DRYNESS IN SJÖGREN'S DISEASE WITH CO2-LASER VERSUS TOPICAL PROMESTRIENE (2026-03-03) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Clinical Study of YTS109 Cells for the Treatment of R/R Autoimmune Diseases (2026-03-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Medico-economic and Quality of Life Impact of Sjogren-associated Small Fiber Neuropathy (2026-02-05) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 2 Study on the Safety and Efficacy of the Anti-BAFF-R Monoclonal Antibody, ESG206, in Patients With Primary Sjogren Syndrome (2026-02-03) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Biopsy Based Study to Understand Mechanism of Action of Ianalumab in Salivary Glands and Explore Relationships With Clinical Assessments. (2026-02-02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research (2026-01-22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Non-gastric mucosa-associated lymphoid tissue lymphomas: a narrative review of pathogenesis, diagnosis, and treatment strategies. (2025/12/31) ♡
• Discover Potential New Epitopes through Post-Translational Modification in Sjögren's Disease. (2025/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An Association Between Autoimmune Hepatitis (AIH) and Immunoglobulin G4-Related Disease (IgG4-RD) in a Male Diagnosed With Primary Sjögren's Syndrome (SJS): A Case-Based Review. (2025/12/31) ♡
• Systemic Lupus Erythematosus and Acute Transverse Myelitis: An Unusual Association-A Case Report. (2025/12/30) ♡
• Establishment of Autoreactive CD4(+)CD8(+) T Cell Hybridomas from Sjögren's Disease Model, SATB1 Conditional Knockout Mice. (2025/12/30) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Ascher ring associated with peripheral deep stromal opacities: A case report. (2025/12/30) ♡
• Application of Fully Convolutional Neural Networks in the Assessment of Cerebral White Matter Involvement in Primary Sjögren's Syndrome. (2025/12/29) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Primary Sjögren's Syndrome Presenting With Severe Hypokalemia Due to Distal Renal Tubular Acidosis: A Case Report. (2025/12/29) ♡
• The Distinct Monocyte Subsets and Intercellular Communication in Primary Sjögren's Syndrome Revealed by Single-Cell RNA Sequencing. (2025/12/27) ♡
• Unveiling the dual nature of late-onset systemic lupus erythematosus: A cross-sectional study. (2025/12/27) ♡
• The relationship between the biological biomarker lnc-DC and female patients with Sjögren's disease. (2025/12/26) ♡
• Correlated Expression of Notch2 and ADAM17 in Primary Sjögren's Syndrome Salivary Glands. (2025/12/26) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Thrombotic Storm: A Challenging Case of Catastrophic Antiphospholipid Syndrome. (2025/12/26) ♡
• Spatial multi-omics profiling uncovers metabolic heterogeneity in Sjögren's syndrome and identifies PS(36:1) as a potential therapeutic target. (2025/12/24) ♡
• Predicted T-Cell and B-Cell Epitopes of NIS: Where Do Sjögren's Syndrome and Hashimoto's Thyroiditis Converge? (2025/12/24) ♡
• Identification of Sjögren's disease-associated T cell receptor motifs through deep sequencing. (2025/12/22) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Hypokalemic rhabdomyolysis due to concurrent distal renal tubular acidosis and Fanconi syndrome in a pediatric patient with Sjögren syndrome. (2025/12/22) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Fatal West Nile Encephalomyelitis in a Young Woman with Hypoparathyroidism and Sjögren's Syndrome. Molecular Insights into Viral Neuro-Invasivity. (2025/12/22) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Efficacy and safety of iguratimod in patients with primary Sjögren's syndrome: a multicentre randomised controlled trial. (2025/12/21) ♡
• Causal Relationships Between the Oral Microbiome and Autoimmune Diseases: A Mendelian Randomization Study. (2025/12/20) ♡
• Frailty and associated risk factors in patients with Sjögren's disease: a cross-sectional study. (2025/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Adrenal Crisis Masquerading as Sepsis in a Patient With Autoimmune Multimorbidity: A Diagnostic Challenge on the Acute Medical Ward. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Oral Manifestations of Sjögren's Syndrome: Recognition, Management, and Interdisciplinary Care. (2025/12/19) ♡
• [Single-cell RNA sequencing of B cells reveals molecular typing in Sjögren syndrome]. (2025/12/18) ♡
• [Untargeted metabolomics reveals differential serum metabolites and metabolic pathways in patients with primary Sjögren syndrome and thrombocytopenia]. (2025/12/18) ♡
• [Clinical efficacy and safety of rituximab in treating renal injury in primary Sjögren syndrome]. (2025/12/18) ♡
• [Clinical characteristics, efficacy and safety of antifibrotic agents in elderly patients with connective tissue disease-associated interstitial lung disease]. (2025/12/18) ♡
• CD48, CD69, and TIGIT as diagnostic biomarkers for primary Sjögren's syndrome: an integrated machine learning and multi-disease discrimination validation study. (2025/12/16) ♡
• Acquired Hemophilia A in Sjögren's Syndrome: An Uncommon Bleeding Disorder Masked by Antiplatelet Use. (2025/12/15) ♡
• Prevalence of Small A-Delta Fiber Neuropathy in Sjögren's Disease: Findings from a Cohort Study. (2025/12/13) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Low-Grade B-cell Lymphoma in Primary Sjögren's Syndrome: A Case Report. (2025/12/13) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Complete Heart Block in the Fetus: An Antenatal Complication of Sjögren's Syndrome. (2025/12/11) ♡

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