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Huntington's disease

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (74)Meta-analysis (18)Treatment guideline (1)Systematic review (22)Randomized trial (21)Phase 3 study (12)Clinical trial (304)Review article (501)Early-stage study (phase 1 or 2) (13)Laboratory or animal research (84)Case report (42)Commentary or editorial (37)Retracted Publication (4) Only studies currently recruiting participants (27)

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Publications and studies (1906)

• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. [Huntington's disease presenting with schizophreniform psychosis and narcolepsy in the premotor phase]. (2025/12/28) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Activation of the Na/K-ATPase oxidant amplification loop by uremic toxins drives adipocyte dysfunction in vitro. (2025/12/28) ♡
• Transcriptomics-based analysis of key genes and potential mechanism and therapeutic agents in cadmium-induced esophageal squamous cell carcinoma progression. (2025/12/25) ♡
• Role of Exercise in Visceral Adipose Tissue Inflammation and Macrophage Polarization in Hypertensive Mice. (2025/12/25) ♡
• Unraveling impaired awareness: experiences of people with dementia, Huntington's disease and Korsakoff's syndrome, and their informal caregivers. (2025/12/22) ♡
• Treatment of Huntington's disease with a pan-HTT-targeting CRISPR nuclease. (2025/12/22) ♡
• Huntingtin in the amygdaloid basolateral complex is correlated with Vonsattel staging in Huntington's disease. (2025/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Ubiquitin signatures on aggregating proteins in neurodegeneration. (2025/12/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Stress and Acute Coronary Syndrome. (2025/12/20) ♡
• PPARδ activation in microglia drives a transcriptional response that primes phagocytic function while countering inflammatory activation. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Extracellular vesicle-based therapies for neurodegenerative diseases. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Sigma receptors and mitochondria-associated ER membranes are converging therapeutic targets for Alzheimer's disease. (2025/12/19) ♡
• Preclinical evaluation of [(11)C]CHDI-009R for quantification of mutant huntingtin aggregates. (2025/12/18) ♡
• Correction to 'Impaired nick recognition and ligation efficiency by LIG1 K845N variant linked to Huntington's disease'. (2025/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Pridopidine, a Potent and Selective Therapeutic Sigma-1 Receptor (S1R) Agonist for Treating Neurodegenerative Diseases. (2025/12/17) ♡
• International Expert Delphi Consensus on Endoscopic Ultrasound-guided Portosystemic Pressure Gradient: Best Practices and Future Directions. (2025/12/16) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The Impact of Neurotoxin Proteins Trafficked by Primary Cilia and Extracellular Vesicles in Neurodegenerative Diseases. (2025/12/15) ♡
• Striatal pathology in Spinocerebellar Ataxia Type 1 mice: A comparative study with Huntington's disease. (2025/12/13) ♡
• Neural and biomarker correlates of the Parkinson's Disease-Cognitive Rating Scale in Huntington's disease. (2025/12/13) ♡
• A shared DNA-repeat toxicity threshold, reached somatically at cell-type-specific rates, unites cortical and striatal neurodegeneration in Huntington's disease. (2025/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Leveraging microbiome-based interventions to improve the management of neurodegenerative diseases: evidence for effects along the microbiota-gut-brain axis. (2025/12/11) ♡
• An acyclic nucleic acid-modified siRNA targeting CAG expansions for polyglutamine disease treatment. (2025/12/11) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. AMT-130 gene therapy: a promising disease-modifying approach for Huntington's disease. (2025/12/10) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Targeting Cathepsins in Neurodegeneration: Biochemical Advances. (2025/12/09) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A narrative review on the therapeutic potential of stem cells in neurodegenerative diseases: advances, insights, and challenges. (2025/12/09) ♡
• Striatal ensembles specify and control granular forelimb actions. (2025/12/08) ♡
• Odds of Developing Overweight or Obesity Increase with Height Decile in Tall Healthy Weight Kindergarteners: Longitudinal Results from the West Virginia Coronary Artery Risk Detection In Appalachian Communities (WV CARDIAC) Project. (2025/12/08) ♡
• Application of multiple parallel mineralization method to grow lettuce, Swiss chard, and peppers in a simplified deep flow technique hydroponic system. (2025/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Beyond oxidative stress: Ferroptosis as a novel orchestrator in neurodegenerative disorders. (2025/12/05) ♡
• The Hidden Burden of Gastroparesis in Chronic Kidney Disease: Evidence from Inpatient and Outpatient Cohorts for Personalized Care. (2025/12/04) ♡
• Global, Regional, and National Burden of Cardiovascular Diseases and Risk Factors in 204 Countries and Territories, 1990-2023. (2025/12/02) ♡
• Calcium bridges built by mitochondria-associated endoplasmic reticulum membranes: potential targets for neural repair in neurological diseases. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Natural products proposed for the management of Huntington's disease (HD): a comprehensive review. (2025/12/01) ♡
• Type and position of repeat interruptions as determinants of disease severity and expansion size in Friedreich ataxia. (2025/12/01) ♡
• Systematic reviewiAll research on one question is searched according to fixed rules and compared side by side, so that no studies with poor outcomes are missed. Risks and Benefits of Gastrostomy in Non-Motor Neurone Disease Progressive Neurological Diseases: A Systematic Review. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Animal models of Huntington's disease. Pros and cons. (2025/12/01) ♡
• A Mutation in Vesicular Acetylcholine Transporter Increases Tubulin Acetylation Compromising Synaptic Vesicle Transport. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Overview of Huntington's Disease and Emerging Treatment Strategies: A Narrative Review. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Dynamics of autophagy in response to high linear energy transfer radiation and cancer. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The cognitive cerebellum: a hub for motor, emotional, and executive control. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Machine Learning Approaches for Optimizing Drug Combinations in Neurodegenerative Diseases: A Brief Review. (2025/11/30) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Atrazine Induces Reproductive Toxicity in an In Vitro Spermatogenesis (IVS) Model. (2025/11/28) ♡
• DNA extrusion size determines pathway choice during CAG repeat expansion. (2025/11/26) ♡
• Fructose and follistatin potentiate acute MASLD during complete hepatic insulin resistance. (2025/11/24) ♡
• Comparative Multi-Omics Analysis Identifies Shared Transcriptomic Signatures and Therapeutic Targets in Alzheimer's, Parkinson's, and Huntington's Diseases. (2025/11/24) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Huntington's Disease Research Over Six Decades: Global Insights, Gaps, and Future Directions. (2025/11/23) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Mechanistic Interplay of Gut Microbiota and Blood-Brain Barrier Integrity in Neurodegenerative Diseases. (2025/11/22) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Glycosphingolipids in Dementia: Insights from Mass Spectrometry and Systems Biology Approaches. (2025/11/22) ♡
• Corrigendum to "Examining balance and the likelihood of falls in Huntington's disease". [Clin. Parkinsonism Relat. Dis. 13 (2025) 100399]. (2025/11/22) ♡
• Blood Trihalomethane Concentrations and Blood Pressure during and after Pregnancy: A Cohort Study in China. (2025/11/18) ♡

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