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Bowel cancer (metastatic)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest quality evidence only (210)Meta-analysis (41)Treatment guideline (1)Randomized trial (127)Systematic review (24)Phase 3 study (17)Clinical trial (717)Review article (227)Early study (phase 1 or 2) (49)Case report (279)Laboratory or animal study (45)Commentary or editorial (19)Retracted Publication (4) Only studies currently recruiting participants (42)

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Publications and studies (2665)

• The edible ethanol extract of Rosa hybrida suppresses colon cancer progression by inhibiting the proliferation-cell signaling metastasis axis. (2025/02/01) ♡
• Comparing the trend of colorectal cancer before and after the implementation of the Population-Based National Cancer Registry in Iran. (2025/01/31) ♡
• Yanghe decoction inhibits inflammation-induced lung metastasis or colorectal cancer. (2025/01/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Trifluridine/tipiracil regimen in combination with bevacizumab for metastatic colorectal cancer in the third line: an expert opinion. (2025/01/22) ♡
• TROPHIT1—a randomized, open-label, multicenter, phase II/III trial of sacituzumab govitecan compared to standard of care in metastatic colorectal cancer patients. (2025/01/17) ♡
• Pooled safety analysis of two phase 3 studies investigating trifluridine/tipiracil plus bevacizumab in patients with metastatic colorectal cancer. (2025/01/16) ♡
• Polydatin enhances oxaliplatin-induced cell death by activating NOX5-ROS-mediated DNA damage and ER stress in colon cancer cells. (2025/01/09) ♡
• Deciphering the oncogenic network: how C1QTNF1-AS1 modulates osteosarcoma through miR-34a-5p and glycolytic pathways. (2025/01/09) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Case Report: Metastatic involvement of the acromioclavicular joint in a patient with papillary carcinoma of the ureter. (2025/01/08) ♡
• Anti-EGFR re-challenge with chemotherapy in RAS wild-type advanced colorectal cancer (A-REPEAT study): efficacy and correlations with tissue and plasma genotyping. (2025/01/08) ♡
• Predictive and prognostic nomogram models for liver metastasis in colorectal neuroendocrine neoplasms: a large population study. (2025/01/07) ♡
• Unveiling the role of ASPP1 in cancer progression: pan-cancer bioinformatics and experimental validation in colorectal cancer. (2025/01/02) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. An unusual presentation of oral metastasis of mucinous colorectal adenocarcinoma: A rare clinical entity and diagnostic challenge. (2025/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Evaluation of serum mid-infrared spectroscopy as a new prognostic marker for first-line bevacizumab based chemotherapy in metastatic colorectal cancer. (2025/01/01) ♡
• Revisiting Luteolin Against the Mediators of Human Metastatic Colorectal Carcinoma: A Biomolecular Approach. (2025/01/01) ♡
• Associations of blood lipids and LDL cholesterol lowering drug targets with colorectal cancer risk: a Mendelian randomization study. (2025/01/01) ♡
• Clinicopathologic stratification demonstrates survival differences between endometrial carcinomas with mismatch repair deficiency and no specific molecular profile: a cohort study. (2025/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Double trouble: Synchronous T-cell lymphoma and colonic adenocarcinoma. (2025/01/01) ♡
• Biomimetic Nano-delivery of Small-Molecule Piceatannol Modulates Tumor Stemness and Suppresses Colorectal Cancer Metastasis via Hippo/YAP1/Sox9 Signaling. (2025/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Design of a Randomized Sham-Controlled Trial: Strengthening Positive Treatment Expectations Using a Communication Model for Maximized Antiemetic Effects of Acupuncture and Antiemetics During Emetogenic Neo-/Adjuvant Chemotherapy. (2025/01/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Atypical Intestinal Metastases from Invasive Lobular Carcinoma of the Breast: Two Surgical Cases Mimicking Primary Gastrointestinal Tumors. (2025/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comprehensive Analysis of Gut Microbiota Signatures in Metastatic Colorectal Cancer (2025-12-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Preoperative Immunotherapy (Pembrolizumab) for Patients With Colorectal Cancer and Resectable Hepatic Metastases (2025-12-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. NALIRIFOX Plus Targeted Therapy Versus FOLFOX Plus Targeted Therapy as First-line Treatment for Metastatic Colorectal Cancer (2025-12-30) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. STIL101 for Injection for the Treatment of Locally Advanced, Metastatic or Unresectable Pancreatic Cancer, Colorectal Cancer, Renal Cell Cancer, Cervical Cancer and Melanoma (2025-12-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A Study of Select Drug Combinations in Adult Patients With Advanced/Metastatic BRAF V600 Colorectal Cancer (2025-12-24) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Clinical Study of Second-line Treatment in Advanced Colorectal Cancer With Chemotherapy With Bevacizumab or Cetuximab (2025-12-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. First-in-human trial of STC-1010, an Immunotherapy, in Patients With Unresectable Locally Advanced for Metastatic Colorectal Cancer (2025-12-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase III Study in First-line Treatment of Patients With Metastatic Colorectal Cancer Who Are Not Candidate for Intensive Therapy. (2025-12-22) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Basket Study of Tucatinib and Trastuzumab in Solid Tumors With HER2 Alterations (2025-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. GRECCAR 8: Primary Tumor Resection in Rectal Cancer With Unresectable Metastasis (2025-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. KZR-261 in Subjects With Advanced Solid Malignancies (2025-12-19) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Cetuximab and Envafolimab Plus mFolfoxiri as First-line Treatment for RAS/BRAF Wild Type, MSS, Unresectable Left-side Metastatic Colorectal Cancer (2025-12-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. A First-in-Human, Phase 1 Study of TST003 in Subjects With Solid Tumors (2025-12-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. ValProic Acid to Potentiate Anti-EGFR Treatment Efficacy and Prevent/Revert Resistance in Colorectal Cancer (2025-12-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. STREAM-2: Second-line Treatment With Regorafenib in Advanced Ras Mutant Colorectal Cancer (2025-12-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Phase 1 Study Evaluating the Safety and PK of ADU-1805 in Advanced Solid Tumors (2025-12-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Using ctDNA Methylation to Monitor Metastatic Colorectal Cancer Treatment (PROMET) (2025-12-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Infusion System for Hepatic Cancer (2025-12-15) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Study to Assess Adverse Events and Change in Disease Activity in Previously Treated Adult Participants Receiving Intravenous (IV) ABBV-400 With Unresectable Metastatic Colorectal Cancer in Combination With IV Fluorouracil, Folinic Acid, and Bevacizumab (2025-12-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. - IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable/Proficient Mismatch Repair (MSS/PMMR) Metastatic Colorectal Cancer Without Active Liver Metastases (2025-12-12) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Combination of Compound Kushen injection with first-line treatment versus first-line treatment alone for advanced colorectal cancer: a study protocol for a multicenter, open-label, randomized controlled trial. (2024/12/31) ♡
• Regorafenib with or without chemotherapy/immunotherapy in second-line treatment of metastatic colorectal cancer during the COVID-19 pandemic: a single-center retrospective analysis. (2024/12/31) ♡
• Later lines of systemic therapy in patients with metastatic colorectal cancer: real-world data from a setting with barriers to access cancer therapies. (2024/12/31) ♡
• Genomic profiles and their associations with microsatellite instability status, tumor mutational burden, and programmed death ligand 1 expression in Chinese patients with colorectal cancer. (2024/12/31) ♡
• Colorectal metastasis from gastric cancer: insights from a 14-year case series at a tertiary hospital. (2024/12/31) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Insight into dipeptidase 1: structure, function, and mechanism in gastrointestinal cancer diseases. (2024/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A 21-Year-Old Male With Metastatic Colorectal Cancer: A Case Report and Literature Overview of Early-Onset Colorectal Cancer. (2024/12/31) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Aphthous-Like Stomatitis in a Patient Receiving Panitumumab. (2024/12/31) ♡
• Factors Influencing the Duration of Maintenance Therapy in Metastatic Colorectal Cancer. (2024/12/30) ♡

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