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Cystic fibrosis

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Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchHighest evidence only (96)Meta-analysis (21)Treatment guideline (8)Systematic review (33)Randomized trial (27)Phase 3 study (7)Clinical trial (707)Review article (354)Early study (phase 1 or 2) (16)Case report (129)Laboratory or animal study (55)Commentary or editorial (60) Studies currently recruiting participants only (30)

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Publications and studies (2553)

• Virulent strains of Pseudomonas aeruginosa are more disruptive during invasion of a microbial model community. (2026/01/07) ♡
• Comparative volatilomics identifies ubiquitous sulfur compounds inhibiting the fungal pathogen Rasamsonia argillacea. (2026/01/06) ♡
• Bronchial epithelial cell-derived extracellular vesicles drive inflammasome activation and NTHi infection in COPD. (2026/01/02) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Validation of the Italian version of Bronchiectasis Quality of Life Questionnaire. (2026/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Feasibility of Using Continuous Glucose Monitoring to Detect Glycemic Abnormalities in Children with Cystic Fibrosis. (2026/01/01) ♡
• Personalized Medicine in Cystic Fibrosis: Characterization of Eight Rare CFTR Variants in Intestinal Organoids and Cellular Models. (2026/01/01) ♡
• Randomized researchiParticipants were divided into groups by lottery and compared with each other. This reduces the chance that a difference is due to something other than the treatment. Effectiveness of nutritional intervention package versus conventional nutritional counseling in pediatric cystic fibrosis: A randomized controlled trial. (2026/01/01) ♡
• Primary human intestinal organoids with biallelic UNC45A variants suggest role of cystic fibrosis transmembrane conductance regulator in pathogenesis of UNC45A-related intestinal disorder. (2026/01/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Occult constipation in pediatric irritable bowel syndrome and functional abdominal pain-not otherwise specified: Considerations on the recent ESPGHAN/NASPGHAN guidelines. (2026/01/01) ♡
• Peak nasal inspiratory flow as an adjunct measure of respiratory function in paediatric cystic fibrosis. (2026/01/01) ♡
• Persistent plasma and RBC fatty acid abnormalities in children and adolescents with cystic fibrosis on highly effective CFTR modulators. (2026/01/01) ♡
• Association of food insecurity with feeding tube dependence and increased healthcare utilization in pediatric gastroenterology. (2026/01/01) ♡
• Exposure of dams to Elexacaftor/ Tezacaftor/Ivacaftor during pregnancy and breastfeeding induces reversible alterations in newborn wild type CD-1 mice. (2026/01/01) ♡
• Corrigendum to "Results of a clinical trial of ANG003, a non-porcine pancreatic enzyme replacement therapy, in people with cystic fibrosis" [Journal of Cystic Fibrosis Original Article Articles in Press July 31, 2025]. (2026/01/01) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Intestinal adaptations increase basolateral intestinal glucose uptake and glycolysis in a mouse model of cystic fibrosis. (2026/01/01) ♡
• Diet quality in Brazilian adolescents with cystic fibrosis. (2026/01/01) ♡
• Pregnancies in women with cystic fibrosis in the era of CFTR modulators: Current challenges and future perspectives. Insights from the Italian cystic fibrosis registry. (2026/01/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Strategies for the identification of people with cystic fibrosis responsive to CFTR modulator triple combinations. (2026/01/01) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Multicentre preclinical profiling of apramycin for the treatment of nontuberculous mycobacteria. (2026/01/01) ♡
• Building a national headache medicine research network: The BE WELL with Migraine Champion Providers Network™. (2026/01/01) ♡
• Redox Profile, Inflammatory and Cardiac Autonomic Nervous Activity of Children and Adolescents With Cystic Fibrosis. (2026/01/01) ♡
• Increased Interleukin-17C Production by the Toll-Like Receptor 3 Ligand Poly(I:C) in Primary Cystic Fibrosis Airway Epithelial Cells. (2026/01/01) ♡
• Stage analysis of gastric cancer: a bioinformatic approach. (2026/01/01) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Trikafta in Cystic Fibrosis Patients (2026-08-11) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. Study to Evaluate Elexacaftor/Tezacaftor/Ivacaftor (ELX/TEZ/IVA) Long-term Safety and Efficacy in Subjects Without F508del (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Phase 2 Study to Assess the Safety and Efficacy of ANG003 (2026-08-11) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Evaluation of VX-828 in Healthy Participants and in Participants With Cystic Fibrosis (2026-08-10) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis (2026-08-06) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study to Test the Safety and Effects of Inhaled GDC-6988 in Participants With Muco-obstructive Disease (2026-08-04) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Heart and Blood Vessels Health in People With Cystic Fibrosis (2026-08-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Streamlined Treatment of Pulmonary Exacerbations in Pediatrics (2026-08-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Glucose Metabolism in Cystic Fibrosis Related Diabetes (CFRD) (2026-08-03) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Continuous Glucose Monitoring and OGTT Screen for Cystic Fibrosis Related Diabetes in Cystic Fibrosis (2026-07-31) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Impact of Telerehabilitation Training on Pediatric Cystic Fibrosis Patients: An Exploratory Study (2026-07-30) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Study to Access Activity and Safety With SAR445399 Compared With Placebo in Participants Aged 18 to 80 Years of Age With Non-Cystic Fibrosis Bronchiectasis (2026-07-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Implementation of a Clinical Tool to Improve Waitlist Mortality in Patients With Cystic Fibrosis (2026-07-29) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Autogenic Drainage Versus Mechanical Percussion in Children With Cystic Fibrosis (2026-07-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. HERO-2: Home-Reported Outcomes With CFTR Modulator Therapy (2026-07-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. HFCWO in Children With Non-CF Bronchiectasis (2026-07-28) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 1a/1b Study to Investigate the Safety, Tolerability, Microbiological Response, and Pharmacokinetics of Inhaled Rev-56 in Adult Healthy Volunteers and Adult Non-cystic Fibrosis Bronchiectasis (NCFB) Patients With Chronic P. Aeruginosa (2026-07-28) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Natural History of Noncirrhotic Portal Hypertension (2026-07-28) ♡
• Phase 3 studyiResearch in a large group of patients, the final step before a treatment can be approved. What comes out here carries significant weight. A Study Evaluating the Long-term Safety and Efficacy of VX-121 Combination Therapy (2026-07-21) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Peer i-Coaching for Activated Self-Management Optimization in Adolescents and Young Adults With Chronic Conditions (2026-07-17) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Role of Genetic Factors in the Development of Lung Disease (2026-07-17) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. A Phase 1b/2 Trial of the Safety and Microbiological Activity of Bacteriophage Therapy in Cystic Fibrosis Subjects Colonized With Pseudomonas Aeruginosa (2026-07-16) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Dose Escalation Study Evaluating the Safety and Pharmacokinetics of VX-581 in Healthy Participants (2026-07-16) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Comparing Expectorated and Induced Sputum and Pharyngeal Swabs for Cultures, AFB Smears, and Cytokines in Pulmonary Nontuberculous Mycobacterial Infection (2026-07-16) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity (2026-07-16) ♡
• Early-stage study (phase 1 or 2)iEarly research in a small group, primarily aimed at safety and dosage. Whether it actually works still needs to be determined afterward. Bacteriophages for Adults With Cystic Fibrosis and Chronic Achromobacter Lung Infection (2026-07-15) ♡

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