← All diseases Muscles and connective tissue

Systemic sclerosis (scleroderma)

Automatically tracked from PubMed and ClinicalTrials.gov, newest on top. Nothing ever disappears here: what you keep in your favorites remains findable. · RSS feed of this disease · only the strongest evidence

Search Period All yearsLast 12 monthsLast 5 years Topic All topicsGeneralNutrition and dietAlternative treatment methods Type of research Any type of researchStrongest evidence only (63)Meta-analysis (20)Treatment guideline (3)Systematic review (23)Randomized trial (11)Phase 3 study (6)Clinical trial (613)Review article (412)Early study (phase 1 or 2) (29)Case report (177)Laboratory or animal study (26)Commentary or editorial (42)Retracted publication (2) Studies currently recruiting participants only (39)

Filter

Publications and studies (2095)

• Rituximab-induced Acute Thrombocytopenia in Systemic Sclerosis: A Case Report of Two Cases. (2025/12/25) ♡
• Clinical trialiResearch in patients, without randomization between groups. Useful, but less certain than a randomized trial. Effects of multimodal nutritional intervention on nutritional status and clinical outcomes in patients with systemic sclerosis: study protocol for a randomised controlled trial. (2025/12/25) ♡
• Temporal Dynamics of Pulmonary Fibrosis and Immune Dysregulation in a Collagen V-Driven Systemic Sclerosis Model. (2025/12/24) ♡
• Laboratory or animal researchiNo research in humans yet. Promising in a test tube or in mice unfortunately means nothing for patients. Soquelitinib inhibition of IL-2-inducible T cell kinase ameliorates lung damage in murine models of systemic sclerosis. (2025/12/23) ♡
• Gut microbial interaction networks control autoimmunity to neuroretina. (2025/12/23) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Acute Hypoxemic Respiratory Failure Caused by Nonspecific Interstitial Pneumonia in Mixed Connective Tissue Disease: A Case Report. (2025/12/23) ♡
• Baricitinib ameliorates skin fibrosis via direct fibroblast suppression and endothelial exosome-mediated paracrine signaling. (2025/12/20) ♡
• The efficacy and safety of tocilizumab in juvenile localised scleroderma patients: a retrospective cohort study in Eastern China. (2025/12/20) ♡
• Molecular insights from skin biopsies: Deciphering microvascular pathology in peripheral vascular diseases. (2025/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Rituximab in Connective Tissue Disease-Associated Interstitial Lung Disease: From Immunopathogenesis to Therapeutic Implications. (2025/12/20) ♡
• Causal Relationships Between the Oral Microbiome and Autoimmune Diseases: A Mendelian Randomization Study. (2025/12/20) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Adipose-Derived Stem Cell, Stromal Vascular Fraction, and Regenerative Cell Enrichment in Fat Grafting: A Systematic Review of Safety and Functional Outcomes. (2025/12/19) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Cheilitis Glandularis: A Case Report of an Unusual Occurrence. (2025/12/19) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Clinical efficacy and mechanisms of hyperbaric oxygen therapy in the treatment of rheumatic and immune diseases. (2025/12/18) ♡
• Identification of Novel Biomarkers and Potential Therapeutic Targets for Systemic Sclerosis: An Integrated Analysis of Plasma Proteome-Wide Mendelian Randomization and Transcriptome. (2025/12/17) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Immunopathogenic Mechanisms in Connective Tissue Disease-Associated Interstitial Lung Disease: Incessant Loop of Immunity to Fibrosis. (2025/12/17) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Phosphodiesterase-4 inhibition in localized scleroderma: A case series of topical roflumilast. (2025/12/15) ♡
• A single-cell cytokine dictionary of human peripheral blood. (2025/12/15) ♡
• The altered T cell landscape in Systemic Sclerosis patients is characterized by dysfunctional type 1 immunity. (2025/12/13) ♡
• Encapsulating Peritoneal Sclerosis. (2025/12/13) ♡
• Mapping the circulating proteome across neurodegeneration: A harmonized, consortium-scale framework for uncovering molecular pathophysiology. (2025/12/12) ♡
• Association of Inflammation-Based Ratios with Endothelial Dysfunction Markers and Clinical Parameters in Limited Cutaneous Systemic Sclerosis. (2025/12/12) ♡
• A single-cell cytokine dictionary of human peripheral blood. (2025/12/12) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. A Review of Cutaneous Viral Infections and Their Potential Role in Neurologic Diseases. (2025/12/11) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Isosorbide Diesters: Mechanistic Insights and Therapeutic Applications in Skin and Neuroinflammatory Disorders. (2025/12/09) ♡
• 3D chromatin-based variant-to-gene maps across 57 human cell types reveal the cellular and genetic architecture of autoimmune disease susceptibility. (2025/12/08) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Chromosomal Instability and Telomere Attrition in Systemic Sclerosis: A Historical Perspective. (2025/12/08) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. A Case Report on a Challenge From Diagnosis to Treatment: Interstitial Lung Disease As the First Manifestation of Systemic Sclerosis Sine Scleroderma. (2025/12/08) ♡
• Racial and ethnic representation in systemic sclerosis clinical trials: a 25-year analysis of ClinicalTrials.gov (1999-2025). (2025/12/08) ♡
• Change in Antinuclear Antibodies After Lung Transplantation in Patients with Systemic Sclerosis. (2025/12/07) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. Systemic sclerosis triggered by bleomycin: a 5-year follow-up. (2025/12/06) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Gut microbiota-neuroinflammation axis: A new mechanism and therapeutic target for comorbid depression in epilepsy. (2025/12/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Infrared thermography for the diagnosis and monitoring of Raynaud's phenomenon: current evidence and future directions. (2025/12/05) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Blood pressure effects of SGLT2 inhibitors and GLP-1 receptor agonists: Mechanisms, trial evidence and Real-world data. (2025/12/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Endothelium glutamate receptors in brain pathology. (2025/12/04) ♡
• Prevalence and severity of complicated Raynaud's phenomenon in limited and diffuse systemic sclerosis: a multicenter study in Iraq. (2025/12/04) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Nailfold capillaroscopy in rheumatic connective tissue diseases. (2025/12/03) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Updates on the role of miR-193b in the pathogenesis of human cancers and other diseases. (2025/12/02) ♡
• Development and Validation of LC-MS/MS Method for Nintedanib and BIBF 1202 Monitoring in Plasma of Patients with Progressive Pulmonary Fibrosis Associated with Systemic Sclerosis. (2025/12/02) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Interleukin in Immune-Mediated Diseases: An Updated Review. (2025/12/01) ♡
• Deciphering distinct pathogenic mechanisms of ankylosing spondylitis and systemic sclerosis via shared biomarkers ZSWIM6 and CCL3L3: Insights from an integrative bioinformatics approach. (2025/12/01) ♡
• Polygenic risk of refractory celiac disease type II and its association with autoimmune diseases: a phenome-wide association study in the UK Biobank. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. The oral microbiome-redox-inflammation axis in neurodegeneration: mechanistic insights and therapeutic perspectives. (2025/12/01) ♡
• Geriatric syndromes in intestinal failure: An accelerated aging phenomenon in middle adulthood patients? (2025/12/01) ♡
• Effect of a gluten-free diet on serum lipopolysaccharide levels and disease progression in multiple sclerosis patients: A 6-month longitudinal study. (2025/12/01) ♡
• Early Detection of Pulmonary Arterial Hypertension in Connective Tissue Disease: A Single-Center Retrospective Study. (2025/12/01) ♡
• Commentary or editorialiAn expert's opinion or commentary, not new research. Systemic Lupus Erythematosus and Multiple Sclerosis Overlap After Adalimumab Therapy: A Case Report. (2025/12/01) ♡
• Description of individual patientsiThe story of one or a couple of patients. Informative, but you cannot infer from it whether something works in general. MASLD-Induced Hyperammonemia With Atypical, Restricted Diffusion Pattern Suggesting Mixed Metabolic and Hypoxic-Anoxic Injury. (2025/12/01) ♡
• A novel microneedle-based delivery of NRF2-overexpressing exosomes for scleroderma therapy. (2025/12/01) ♡
• Review articleiA summary of what is known about a topic, written by experts. Not compiled according to fixed search rules, so the selection of studies may be biased. Tissue-Resident Memory T Cells in Rheumatoid Immune Diseases: Pathogenic Mechanisms and Therapeutic Strategies. (2025/11/30) ♡

↑ Back to top

codex.care does not provide medical advice. Always discuss symptoms, medication, and treatment choices with your own healthcare provider.